Utoguchi Naoki

ウトグチナオキ | Utoguchi Naoki

Affiliation and department：
Job title： Professor

Research field (3)： Tumor diagnostics and therapeutics , Pharmacology , Pharmaceuticals - health and biochemistry

Research keywords (5)：がん免疫 , ターゲティング , DDS , 薬剤学 , Pharmaceutics

Research theme for competitive and other funds (11)：

2020 - 2023 Development of novel immunotherapy for malignant brain tumors targeting tumor vascular mimicry
2015 - 2018 腫瘍細胞が構築する擬似血管を標的とした新規悪性脳腫瘍治療法の開発
2011 - 2014 腫瘍細胞が構築する擬似血管を標的とした新規がん免疫療法の開発
2011 - 2013 In vitro approaches to evaluate placental drug transport by using differentiating JEG-3 human choriocarcinoma cells
2007 - 2009 脳腫瘍血管を標的とした新規悪性脳腫瘍免疫療法の開発

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Papers (68)：

Yoshikazu Sawaguchi, Keiichi Hirata, Ryo Suzuki, Kazuo Maruyama, Naoki Utoguchi. Anti-Obesity Dendritic Cell Vaccine Therapy Targeting Neovascular Vessels in High-Fat-Diet-Fed Mice. BPB Reports. 2022. 5. 5. 95-98
Takamasa Hirai, Ken Kono, Rumi Sawada, Takuya Kuroda, Satoshi Yasuda, Satoko Matsuyama, Akifumi Matsuyama, Naoya Koizumi, Naoki Utoguchi, Hiroyuki Mizuguchi, et al. A selective cytotoxic adenovirus vector for concentration of pluripotent stem cells in human pluripotent stem cell-derived neural progenitor cells. Scientific reports. 2021. 11. 1. 11407-11407
Takamasa Hirai, Anna Sato, Naoya Koizumi, Yoh Kurioka, Yui Suzuki, Junpei Kano, Makie Yamakawa, Tetsuya Nomura, Makiko Fujii, Fuminori Sakurai, et al. The infectivity of progeny adenovirus in the presence of neutralizing antibody. Journal of General Virology. 2021. 102. 4
Adenovirus Fiber can Distribute Itself to the Cell Surface without Membrane Damage. BPB Reports. 2019. 2. 6. 113-118
DC-Based Immunotherapy Using Vascular Endothelial Cells Cultured in Conditioned Medium as a Vaccine Antigen Exerts an Anti-Tumor Effect by Inhibiting Angiogenesis. BPB Reports. 2019. 2. 6. 99-105

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MISC (95)：

Ryo Suzuki, Yusuke Oda, Risa Koshima, Keiichi Hirata, Tetsuya Nomura, Yoichi Negishi, Naoki Utoguchi, Shinsaku Nakagawa, Kazuo Maruyama. Anti-tumor mechanism in IL-12 gene therapy using liposomal bubbles and ultrasound. AIP Conference Proceedings. 2011. 1359. 345-350
鈴木亮, 小田雄介, 宇都口直樹, 丸山一雄, 根岸洋一, 中川晋作. リポソーム型微小気泡(バブルリポソーム)の超音波がん遺伝子治療への応用. 超音波医学. 2010. 37. 6. 701-701
丸山一雄, 鈴木亮, 小田雄介, 平裕一郎, 宇都口直樹. イメージングとDDS 相変化液滴を封入したバブルリポソームの開発と造影・治療への適用. Drug Delivery System. 2010. 25. 3. 264-264
丸山一雄, 鈴木亮, 小田雄介, 西家功人, 平裕一郎, 平田圭一, 宇都口直樹. リポソーム型微小気泡を利用した超音波がん温熱療法の開発. 超音波医学. 2010. 37. 3. 372-372
大竹将太, 小田雄介, 鈴木亮, 宇都口直樹, 岡田直貴, 中川晋作, 丸山一雄. 超音波感受性リポソームを用いた樹状細胞への超音波抗原送達法におけるMHCクラスI抗原提示経路の解析. 日本薬学会年会要旨集. 2010. 130th. 4. 168

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Education (4)：

Professional career (1)：

Work history (6)：

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Awards (1)：

Association Membership(s) (4)：

日本DDS学会 , 日本癌学会 , 日本薬剤学会 , 日本薬学会

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