Sakurama Haruko

サクラマハルコ | Sakurama Haruko

Affiliation and department：
Job title： Junior Associate Professor

Research field (2)： Environmental load reduction/restoration technology , Food sciences

Research keywords (4)：環境浄化 , Applied Microbiology , 酵素化学 , Enzyme Chemistry

Research theme for competitive and other funds (2)：

2018 - 2021 Molecular diagnostics for polychlorinated biphenyl degradation in contaminated soils
2015 - 2018 Creation of novel aromatic-ring hydroxylating dioxygenase with extended substrate specificity toward polychlorinated biphenyls

Papers (15)：

Aina Gotoh, Masafumi Hidaka, Haruko Sakurama, Mamoru Nishimoto, Motomitsu Kitaoka, Mikiyasu Sakanaka, Shinya Fushinobu, Takane Katayama. Substrate recognition mode of a glycoside hydrolase family 42 β-galactosidase from Bifidobacterium longum subspecies infantis (BiBga42A) revealed by crystallographic and mutational analyses. Microbiome Research Reports. 2023. 2. 20
Aina Gotoh, Toshihiko Katoh, Yuta Sugiyama, Shin Kurihara, Yuji Honda, Haruko Sakurama, Taiho Kambe, Hisashi Ashida, Motomitsu Kitaoka, Kenji Yamamoto, et al. Novel substrate specificities of two lacto-N-biosidases towards β-linked galacto-N-biose-containing oligosaccharides of globo H, Gb5, and GA1. Carbohydrate research. 2015. 408. 18-24
Haruko Sakurama, Shigenobu Kishino, Yoshie Uchibori, Yasunori Yonejima, Hisashi Ashida, Keiko Kita, Satomi Takahashi, Jun Ogawa. beta-Glucuronidase from Lactobacillus brevis useful for baicalin hydrolysis belongs to glycoside hydrolase family 30. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 2014. 98. 9. 4021-4032
H. Sakurama, S. Kishino, K. Mihara, A. Ando, K. Kita, S. Takahashi, S. Shimizu, J. Ogawa. Biohydrogenation of C20 polyunsaturated fatty acids by anaerobic bacteria. J. Lipid Res. 2014. 55. 9. 1855-1863
Haruko Sakurama, Masashi Kiyohara, Jun Wada, Yuji Honda, Masanori Yamaguchi, Satoru Fukiya, Atsushi Yokota, Hisashi Ashida, Hidehiko Kumagai, Motomitsu Kitaoka, et al. Lacto-N-biosidase Encoded by a Novel Gene of Bifidobacterium longum Subspecies longum Shows Unique Substrate Specificity and Requires a Designated Chaperone for Its Active Expression. JOURNAL OF BIOLOGICAL CHEMISTRY. 2013. 288. 35. 25194-25206

ｍore...

MISC (4)：

Kishino Shigenobu, Uchibori Yoshie, Sakurama Haruko, Tani Miho, Yonejima Yasunori, Ogawa Jun. 2P-093 Characterization of novel β-glucuronidase derived from Lactobacillus brevis subsp. coagulans. 2014. 66. 130-130
櫻間晴子, 伏信進矢, 北岡本光, 日高將文, 芦田久, 山本憲二, 熊谷英彦, 片山高嶺. Bifidobacterium longum subsp.infantis由来1,3-1,4-α-L-フコシダーゼが有するユニークな基質特異性の構造学的基盤. 腸内細菌学雑誌. 2012. 26. 2
櫻間晴子, 伏信進矢, 北岡本光, 日高將文, 芦田久, 片山高嶺, 山本憲二, 熊谷英彦. 1,3-1,4-α-L-フコシダーゼの結晶構造解析に基づく基質特異性の構造学的基盤. 日本農芸化学会大会講演要旨集(Web). 2012. 2012
S. Yano, W. Wang, Q. Li, K. Matsumoto, H. Sakurama, T. Nakamura, H. Ogino, S. Kakiuchi, M. Hanibuchi, Y. Nishioka, et al. Hepatocyte growth factor induces gefitinib resistance of lung adenocarcinoma with epidermal growth factor receptor-activating mutations (vol 68, pg 9479, 2008). CANCER RESEARCH. 2009. 69. 1. 381-381

Education (2)：

- 2002 Kyoto University
- 2001 Kyoto University Graduate School, Division of Agriculture

Work history (8)：

2016/04 - 現在 Kyoto University of Advanced Science Faculty of Bioenvironmental Science Department of Bioscience and Biotechnology
2014/11 - 2016/03 Yamagata University Graduate School of Science and Engineering
2012/10 - 2014/10 Kyoto University Graduate School of Agriculture
2009/04 - 2012/09 Ishikawa Prefectural University
2007/04 - 2009 Kanazawa University Cancer Research Institute

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