Hakamatsuka Takashi

ハカマツカタカシ | Hakamatsuka Takashi

Affiliation and department：
Job title： Professor

Research field (2)： Pharmaceuticals - chemistry and drug development , Environmental and pharmaceutical development resources

Research keywords (4)： Regulatory Science , Natural Product Chemistry , Pharmacognosy , 化学系薬学

Research theme for competitive and other funds (14)：

2015 - 2017 天然物医薬品の日独双方向国際展開に資する薬用植物の化学的研究
2002 - 2004 Screening for natural bioactive compounds enhancing the gene expression of bone remodeling factors
1998 - 1999 細胞内情報伝達経路に作用する天然生物活性物質の探索とその応用
1994 - 1994 イソフラボン生合成反応を触媒するシトクロムP-450の遺伝子クローニング
1993 - 1994 The Research on the Production of Usefull Compounds by the Control of Regulations in the Biosynthesis of Secondary Metabolism

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Papers (52)：

内山奈穂子, 新井玲子, 田中誠司, 丸山卓郎, 伊藤雅文, 柴原豪了, 武田修己, 小栗志織, 佐々木隆宏, 岡秀樹, et al. 局外生規2022新規収載単味生薬エキスの確認試験及び定量法の設定について. 生薬学雑誌. 2023. 77. 1. 7-23
Kazuaki Kamata, Jin Tatsuzaki, Tsutomu Ishikawa, Ryoko Arai, Takashi Hakamatsuka, Nahoko Uchiyama. HPLC analysis of ammonium glycyrrhizate listed in the European, United States, and Japanese Pharmacopoeias under reported and modifed conditions: revision of the peak assignment for 18α-glycyrrhizin in the European and United States Pharmacopoeias. Journal of natural medicines. 2022
中森俊輔, 日向須美子, 大嶋直浩, 内山奈穂子, 白畑辰弥, 日向昌司, 天倉吉章, 袴塚高志, 合田幸広, 小田口浩, et al. 酸誘発性筋肉痛モデルに対するエフェドリンアルカロイド除去麻黄エキス(EFE)の鎮痛作用の解析. 和漢医薬学会学術大会要旨集. 2022. 39回. 70-70
Hiroko Tokumoto, Eiichi Yamamoto, Takashi Hakamatsuka, Nahoko Uchiyama. A New Method to Visualize the Internal Morphology of Crude Drugs Using High-Resolution X-Ray Computed Tomography. Biological & pharmaceutical bulletin. 2022. 45. 7. 919-925
黄雪丹, 日向須美子, 伊東秀憲, 小田口浩, 内山奈穂子, 日向昌司, 天倉吉章, 袴塚高志, 花輪壽彦, 小林義典. 麻黄エキス、EFE、あるいはエフェドリンアルカロイドを経口投与したマウスの心拍変動解析. 日本東洋医学雑誌. 2022. 73. 別冊. 125-125

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MISC (93)：

水谷佐久美, 河村麻衣子, 黒原崇, 三澤隆史, 出水庸介, 袴塚高志, 花尻瑠理[木倉]. 合成オピオイドnitazene類14化合物の識別法に関する検討. 日本薬学会年会要旨集. 2022. 142年会. 28PO10-05
内山奈穂子, 新井玲子, 田中誠司, 丸山卓郎, 袴塚高志, 伊藤雅文, 柴原豪了, 武田修己, 小栗志織, 佐々木隆宏, et al. 局外生規2022に新規収載予定の単味生薬エキスについて. 日本薬学会年会要旨集. 2022. 142年会. 27PO1-11
新屋和花, 新屋和花, 丸山卓郎, 峠隆之, 林茂樹, 安食菜穂子, 高浦(島田)佳代子, 高浦(島田)佳代子, 袴塚高志, 森田洋行, et al. インドジャボク及び同属植物における含有成分の多様性解析. 日本生薬学会年会講演要旨集. 2021. 67th
政田さやか, 遊佐仁曉, 辻厳一郎, 横尾英知, 細江潤子, 新井玲子, 田中誠司, 出水庸介, 袴塚高志, 合田幸広, et al. Formal total synthesis of kwakhurin, a Pueraria mirifica component, and quantification of miroestrol in P. mirifica-containing food products using relative molar sensitivities of miroestrol to kwakhurin. 天然有機化合物討論会講演要旨集(Web). 2020. 62nd
吉冨太一, 新村萌, 小山忠一, 田辺章二, 神本敏弘, 山本豊, 中川和也, 横倉胤夫, 近藤誠三, 内山奈穂子, et al. Development of an Identification Test for Hampi (HANPI) by Using TLC and the Structural Analysis of the Indicator Components. 生薬学雑誌. 2020. 74. 1

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Books (6)：

Biosynthesis and natural functions of Pueraria isoflavonoids
Pueraria, Medicinal and aromatic plants-Industrial profiles 2002
Biosynthesis and natural functions of Pueraria isoflavonoids
Pueraria, Medicinal and aromatic plants-Industrial profiles, Taylor and Francis, London and New York 2002
Biosynthesis of isoflavone and related compounds in tissue cultures of Pueraria lobata
Dynamic Aspects of Natural Products Chemistry, Molecular Biological Approaches 1997
Biosynthesis of isoflavone and related compounds in tissue cultures of Pueraria lobata
Dynamic Aspects of Natural Products Chemistry, Molecular Biological Approaches, Kodansha and Howard Academic Publisher 1997
Pueraria lobata: In vitro culture and the production of isoflavonoids
Biotechnology in agriculture and forestry 28, Medicinal and aromatic plants VII 1994

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Works (3)：

薬用植物の開発研究
1998 - 2000
血管新生抑制化合物の探索
1997 - 2000
遺伝子発現を変動させる天然化合物の探索
1998 - 1999

Education (3)：

1987 - 1989 The University of Tokyo
1985 - 1987 The University of Tokyo
1981 - 1985 The University of Tokyo Faculty of Pharmaceutical Sciences

Work history (6)：

2022 - 現在 Nihon Pharmaceutical University Faculty of Pharmaceutical Sciences, Division of Pharmaceutical Sciences professor
2013 - 2022 National Institute of Health Sciences Division of Pharmacognosy, Phytochemistry and Narcotics Head
2006 - 2013 National Institute of Health Sciences Division of Pharmacognosy, Phytochemistry and Narcotics Section Chief
2005 - 2005 Tokyo University of Science Faculty of Pharmaceutical Sciences Associate Professor
1995 - 2005 Tokyo University of Science Faculty of Pharmaceutical Sciences Lecturer

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Committee career (1)：

2003 - 2005 日本生薬学会評議員

Awards (2)：

2003 - 日本生薬学会学術奨励賞
2003 - The Japanese Society of Pharmacognosy Award for Young Scientists

Association Membership(s) (6)：

日本生薬学会 , 日本生化学会 , 日本薬学会 , The Japanese Biochemical Society , The Japan Society of Pharmacognosy , The Pharmaceutical Society of Japan

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