Rchr
J-GLOBAL ID：200901088261870153   Update date: Dec. 10, 2024

Sasayama Takashi

ササヤマ タカシ | Sasayama Takashi
Affiliation and department：
Kobe University University Hospital Neurosurgery

About Kobe University University Hospital Neurosurgery


Job title： Associate Professor
Research field  (3)： Tumor diagnostics and therapeutics ,  Tumor biology ,  Neurosurgery
Research theme for competitive and other funds  (32)：
  • 2024 - 2027 A Prognosis Prediction-based Stratification Method to Build an Evidence Base for the Treatment of Traumatic Brain Injury
  • 2023 - 2027 Minimally invasive brain network mapping for preserving brain functions and predicting plasticity
  • 2023 - 2026 Development of the physiologic marker of E/I balance of the human brain
  • 2022 - 2025 Development of new treatments for medulloblastoma targeting macrophage
  • 2022 - 2025 Developments of surgical systems for skull base surgery and surgical education
Show all
Papers (184)：
  • Yusuke Ikeuchi, Masamitsu Nishihara, Kohkichi Hosoda, Noriaki Ashida, Shunsuke Yamanishi, Hiroaki Nagashima, Kazuhiro Tanaka, Yoshihiro Muragaki, Takashi Sasayama. Postoperative Air in the Cisterns or Ventricles Predicts Early Leptomeningeal Disease of Brain Metastases: A Retrospective Study. World neurosurgery. 2024
  • Yosuke Fujimoto, Yuichi Fujita, Kazuhiro Tanaka, Hiroaki Nagashima, Shunsuke Yamanishi, Yusuke Ikeuchi, Hirofumi Iwahashi, Shoji Sanada, Yoshihiro Muragaki, Takashi Sasayama. Clinical Benefits of Photodynamic Therapy Using Talaporfin Sodium in Patients With Isocitrate Dehydrogenase-Wildtype Diagnosed Glioblastoma: A Retrospective Study of 100 Cases. Neurosurgery. 2024
  • Shunsuke Yamanishi, Hiroaki Nagashima, Kazuhiro Tanaka, Takiko Uno, Yusuke Ikeuchi, Hirofumi Iwahashi, Mitsuru Hashiguchi, Shintaro Horii, Tomoo Itoh, Yoshihiro Muragaki, et al. Association of preoperative seizures with reduced expression of soluble CD163, an M2 macrophage marker, in the cerebrospinal fluid in isocitrate dehydrogenase wild-type glioblastoma. Journal of neuro-oncology. 2024
  • Yusuke Ikeuchi, Masaaki Kohta, Shunsuke Yamashita, Shunsuke Yamanishi, Yoji Yamaguchi, Jun Tanaka, Kazuhiro Tanaka, Hidehito Kimura, Atsushi Fujita, Kohkichi Hosoda, et al. Predicting impaired cerebrovascular reactivity and risk of hyperperfusion syndrome in carotid artery stenosis using BeamSAT magnetic resonance imaging. Journal of the neurological sciences. 2024. 463. 123114-123114
  • Takashi Sasayama, Takeshi Hamada, Kazuhiro Tanaka, Hiroaki Nagashima, Shunsuke Yamanishi, Takehiko Ueyama. Potential of GSPT1 as a novel target for glioblastoma therapy. Cell Death & Disease. 2024. 15. 8
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MISC (134)：
  • 中田光俊, 大槻純男, 内田康雄, 中嶋理帆, 篠山隆司, 長嶋宏明, 立石健祐, 齋藤紀彦, 平井希, 棗田学, et al. Multiinstitutional research to identify the blood biomarkers for diagnosing the state of glioblastoma after standard treatment. 日本脳腫瘍学会学術集会プログラム・抄録集. 2022. 40th
  • Hiroaki Nagashima, Kazuhiro Tanaka, Yuichi Fujita, Mitsuru Hashiguchi, Mashahiro Maeyama, Yuichiro Somiya, Takanori Hirose, Tomoo Itoh, Takashi Sasayama. 2-HYDROXYGLUTARATE MAGNETIC RESONANCE SPECTROSCOPY IN ADULT BRAINSTEM GLIOMA PATIENTS. NEURO-ONCOLOGY. 2021. 23. 131-131
  • Kazuhiro Tanaka, Hiroaki Nagashima, Yuichi Fujita, Mitsuru Hashiguchi, Takashi Sasayama. GLIOMA CELLS REPROGRAM SERINE-DEPENDENT ONE-CARBON METABOLISM TO SURVIVE GLUTAMINE STARVATION. NEURO-ONCOLOGY. 2021. 23. 202-202
  • 長嶋宏明, 長嶋宏明, LEE Christine, 立石建祐, 樋口芙未, 田中一寛, 篠山隆司, MILLERT Julie, 脇本浩明, CAHILL Daniel. ポリ(ADP-リボース)グリコヒドロラーゼ阻害はNAD+を隔離し,IDH変異腫瘍細胞におけるアルキル化化学療法の代謝致死性を増強する. 日本分子脳神経外科学会プログラム・抄録集. 2021. 21st
  • 長嶋宏明, 長嶋宏明, 田中一寛, 篠山隆司. PARG阻害はNAD+を隔離し,IDH変異腫瘍細胞におけるアルキル化化学療法の代謝致死性を増強する. 日本癌学会学術総会抄録集(Web). 2021. 80th
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Books (2)：
  • 神経症候群(第2版)III -その他の神経疾患を含めて- / 髄膜肉腫症
    日本臨床 2014
  • Neurosurgery Now 5 グリオーマ その最新知見 / 腫瘍発生の遺伝子解析
    メジカルビュー 2009
Lectures and oral presentations  (237)：
  • 中枢神経悪性リンパ腫の診断バイオマーカーとしてのCXCL13の検討
    (第36回日本脳腫瘍学会 2018)
  • グルタミン飢餓状態のグリオーマ細胞における一炭素代謝の調整と新規治療標的の探索
    (第36回日本脳腫瘍学会 2018)
  • 悪性脳腫瘍に対する光線力学療法 (PDT)の治療経験
    (日本脳神経外科光線力学学会 2018)
  • Interleukin-6 in Cerebrospinal Fluid as a Prognostic Marker for Glioblastoma Patients
    (23rd Annual Scientific Meeting and Education Day of the society for Neuro-Oncology (SNO) 2018)
  • Glutamine deprivation alters one-carbon metabolism to maintain glioma cell survival
    (23rd Annual Scientific Meeting and Education Day of the society for Neuro-Oncology (SNO) 2018)
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Education (2)：
  • 1999 - 2003 Kobe University Graduate School of Medicine
  • 1988 - 1994 Kobe University School of Medicine Faculty of Medicine
Professional career (2)：
  • 医学学士 (神戸大学)
  • 博士(医学) (神戸大学)
Work history (5)：
  • 2020/09 - 現在 神戸大学大学院医学研究科 外科系講座 脳神経外科学分野 教授
  • 2010/04 - 2020/08 Kobe University University Hospital
  • 2007/04 - 2010/03 Kobe University University Hospital
  • 2005/11 - 2007/03 Kobe University University Hospital
  • 2003/10 - 2005/10 Kobe University University Hospital
Committee career (3)：
  • 2019/09 - 現在 日本脳神経外科学会 代議員
  • 2018/05 - 現在 日本脳神経外科コングレス 運営委員
  • 2015/08 - 現在 日本分子脳神経外科学会 学術企画運営委員
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