Rchr
J-GLOBAL ID:200901088741420670   Update date: Mar. 21, 2024

Shibuya Akira

シブヤ アキラ | Shibuya Akira
Affiliation and department:
Job title: Professor
Research field  (2): Hematology and oncology ,  Immunology
Research keywords  (1): 免疫学・血液学
Research theme for competitive and other funds  (29):
  • 2019 - 2020 免疫受容体の機能解析
  • 2018 - 2020 虚血ストレスによる炎症誘導機構の解明とその制御
  • 2016 - 2020 The regulatory mechanisms of innate immune responses by inhibitory immunoreceptors
  • 2016 - 2016 Development of the therapy for allergic airway hypersensitivity by using a phospholipid liposome
  • 2015 - 2016 粘膜上皮ダイイングコードによる炎症応答制御機構の解明
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Papers (372):
  • Y-H, Lin, S, Tahara-Hanaoka, N, Obana, S, Fukuda, Shibuya, Akira. An inhibitory immunoreceptor Allergin-1 regulates the intestinal dysbiosis and barrier function in mice. Int Immunol. 2024
  • S, Tahara, G, Okumura, T, Matsuo, Shibuya, Akira, K, Shibuya. Essential role of CD155 glycosylation in functional binding to DNAM-1 on natural killer cells. Int Immunol. 2024
  • Y-H, Lin, S, Tahara-Hanaoka, Shibuya, Akira. Human basophils promote IgE-dependent oral allergen-induced anaphylaxis in humanized mice. Allergol Int,. 2023
  • Nabekura, Tsukasa, Deborah, Elfira Amalia, Tahara, Saeko, Arai, Yuya, Love, Paul E, Kako, Koichiro, Fukamizu, Akiyoshi, Muratani, Masafumi, Shibuya, Akira. Themis2 regulates natural killer cell memory function and formation. NATURE COMMUNICATIONS. 2023. 14. 1. 7200
  • H, Koizumi, Nakahashi-Oda C, Lyu W, Y, Yamashita-Kanemaru, K, Tabuchi, K., Shibuya, Shibuya, Akira. Development of monoclonal antibodies specific to either CD300AR111 or CD300AQ111 or both. Monoclonal antibodies in immunodiagnosis and immunotherapy. 2023
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Patents (6):
  • ACTIVITY MODULATOR, MEDICINAL AGENT COMPRISING SAME, USE OF CD300A GENE-DEFICIENT MOUSE, AND ANTI-CD300A ANTIBODY
  • Graft-versus-host disease predictingmarker and use thereof
  • 移植片対宿主病予知マーカーおよびその利用
  • 移植片対宿主病予知マーカーおよびその利用
  • 移植片対宿主病予知マーカーおよびその利用
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Books (4):
  • 食品免疫学事典
    日本食品免疫学会 2021
  • Neuro-Oncology Advances
    2021
  • Keynote RA rheumatic & Autoimmune deseases
    2017
  • 臨床免疫・アレルギー科
    2014
Lectures and oral presentations  (530):
  • Tumor-derived soluble CD155 inhibits DNAM-1-mediated tumor immunity
    (AVD IMMUNOLOGY 2024 CONFERENCE 2ND EURO-GLOBAL SUMMIT 2024.9.23-24)
  • CD300a immunoreceptor exacerbates heart injury and adverse remodeling after myocardial infarction and reperfusion in mice
    (第88回日本循環器学会学術集会)
  • Essential role of CD155 glycosylation in functional binding to DNAM-1 on natural killer cells.
    (第52回日本免疫学会学術集会)
  • Themis2 impairs anti-tumor activity of NK cells by suppressing activating NK receptor signaling
    (第52回日本免疫学会学術集会)
  • The C type l ectin r eceptor Clec12b suppresses mast cell activation in the skin and regulates house dust mite induced dermatitis
    (第52回日本免疫学会学術集会)
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Education (1):
  • - 1981 Hokkaido University Faculty of Medicine
Work history (16):
  • 2012/04 - 現在 筑波大学 若手研究者育成推進委員会委員長
  • 2011/10 - 現在 University of Tsukuba Faculty of Medicine
  • 2014/04 - 2021/03 University of Tsukuba Life Science Center of Tsukuba Advanced Research Alliance (TARA)
  • 2013/04 - 2020/03 University of Tsukuba
  • 2011/04 - 2016/03 筑波大学 若手研究者育成推進委員会委員長
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Committee career (33):
  • 2019/01 - 2022/12 日本免疫学会 評議員
  • 2018/01 - 2020/12 日本免疫学会 日本免疫学会設立50周年記念事業実行委員会委員
  • 2004/01 - 2020/12 日本血液学会 評議員
  • 2018/09 - 2020/08 日本血液疾患免疫療法学会 理事
  • 2015/04 - 2020/03 東京医科歯科大学 非常勤講師
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Awards (14):
  • 2020/04 - 科学技術分野の文部科学大臣表彰(研究部門)
  • 2020/02 - 筑波大学Best Faculty Member
  • 2015/11 - 一般財団法人 茨城県科学技術振興財団 つくば賞
  • 2012/03 - 上原記念生命科学財団特定研究奨励賞
  • 2009/02 - 財団法人 高松宮妃癌研究基金 高松宮妃癌研究基金研究奨励賞
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Association Membership(s) (7):
Japanese Society of Immunotherapy for Hematological Disorders ,  The Japanese Cancer Association ,  American Association of Immunologists ,  JAPANESE SOCIETY FOR IMMUNOLOGY ,  THE JAPANESE SOCIETY OF HEMATOLOGY ,  THE JANPANESE SOCIETY OF INTERNAL MEDICINE ,  日本学術会議連携会員
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