Rchr
J-GLOBAL ID：200901088800060799   Update date: Apr. 17, 2024

Claudia Toma

トーマ クラウディア | Claudia Toma
Affiliation and department：
University of the Ryukyus Graduate School of Medicine

About University of the Ryukyus Graduate School of Medicine


Job title： Associate Professor
Homepage URL  (1)： http://bacteriology-u-ryukyu.com
Research field  (1)： Bacteriology
Research keywords  (4)： 上皮細胞 ,  細胞間接着装置 ,  レプトスピラ ,  Bacterial Pathogenesis
Research theme for competitive and other funds  (13)：
  • 2021 - 2024 病原性レプトスピラによる細胞間接着装置の破壊戦略の解明
  • 2022 - 人獣共通病原菌レプトスピラの皮膚突破戦略の解明:早期診断と予防への応用
  • 2018 - 2021 腎近位尿細管上皮細胞を足場とするレプトスピラの感染機構の解明
  • 2015 - 2018 病原性レプトスピラによる上皮細胞感染戦略
  • 2012 - 2013 病原性レプトスピラの宿主細胞への侵入機構
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Papers (67)：
  • Romina Tokumon, Isabel Sebastián, Bruno M Humbel, Nobuhiko Okura, Hidenori Yamanaka, Tetsu Yamashiro, Claudia Toma. Degradation of p0071 and p120-catenin during adherens junction disassembly by Leptospira interrogans. Frontiers in cellular and infection microbiology. 2023. 13. 1228051-1228051
  • Yukuto Sato, Idam Hermawan, Tetsuya Kakita, Sho Okano, Hideyuki Imai, Hiroto Nagai, Ryosuke Kimura, Tetsu Yamashiro, Tadashi Kajita, Claudia Toma. Analysis of human clinical and environmental Leptospira to elucidate the eco-epidemiology of leptospirosis in Yaeyama, subtropical Japan. PLOS Neglected Tropical Diseases. 2022. 16. 3. e0010234-e0010234
  • Isabel Sebastián, Nobuhiko Okura, Bruno M. Humbel, Jun Xu, Idam Hermawan, Chiaki Matsuura, Malgorzata Hall, Chitoshi Takayama, Tetsu Yamashiro, Shuichi Nakamura, et al. Disassembly of the apical junctional complex during the transmigration of Leptospira interrogans across polarized renal proximal tubule epithelial cells. Cellular Microbiology. 2021. 23. 9
  • Chandika D. Gamage, Yukuto Sato, Ryosuke Kimura, Tetsu Yamashiro, Claudia Toma. Understanding leptospirosis eco-epidemiology by environmental DNA metabarcoding of irrigation water from two agro-ecological regions of Sri Lanka. PLOS Neglected Tropical Diseases. 2020. 14. 7. e0008437
  • Toma C, Suzuki T. Evaluation of Intracellular Trafficking in Macrophages. Methods in molecular biology (Clifton, N.J.). 2020. 2134. 199-206
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MISC (21)：
  • TOKUMON Romina, SEBASTIAN Isabel, YAMASHIRO Tetsu, TOMA Claudia. Degradation of p120-catenin proteins during leptospiral disruption of the junctional complex. 日本細菌学雑誌(Web). 2023. 78. 1
  • TOKUMON Romina, SEBASTIAN Isabel, HASHIMOTO Yuta, YAMASHIRO Tetsu, TOMA Claudia. Leptospira interrogans induces decrease of proteins involved in junction stabilization. 日本細菌学雑誌(Web). 2022. 77. 1
  • SEBASTIAN Isabel, OKURA Nobuhiko, HUMBEL Bruno M., XU Jun, HALL Malgorzata, TAKAYAMA Chitoshi, YAMASHIRO Tetsu, NAKAMURA Shuichi, TOMA Claudia. Strategies used by Leptospira interrogans to disassemble the epithelial apical junctional complex. 日本細菌学雑誌(Web). 2021. 76. 1
  • GAMAGE Chandika, SATO Yukuto, HERMAWAN Idam, RANASINGHE Gayani, SENARATHNE Pavani, HEWAVITHARANA Pasan, KOIZUMI Nobuo, TOMA Claudia. Isolation and characterization of soil inhabited Leptospira species from two agro-ecological regions of Sri Lanka. 日本熱帯医学会大会プログラム抄録集. 2019. 60th
  • HERMAWAN Idam, GAMAGE Chandika, MATSUURA Chiaki, SATO Yukuto, KAKITA Tetsuya, YAMASHIRO Tetsu, TOMA Claudia. Characterizing Genetically Pathogenic Leptospira from Okinawa. レプトスピラ・シンポジウム抄録(CD-ROM). 2019. 56th
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Patents (2)：
  • レプトスピラ症の診断に用いるレプトスピラ抗原検出用抗体
  • Antibodies to detect a leptospiral antigen for the diagnosis of leptospirosis
Lectures and oral presentations  (12)：
  • レプトスピラ症の早期診断:尿中抗原を標的にする診断法の開発
    (ライフサイエンス 新技術説明会 (Japan Science and Technology Agency) 2020)
  • Environmental DNA metabarcoding to understand the ecology of leptospirosis
    (World Congress on Leptospirosis 2019)
  • Leptospira interrogans translocation across renal proximal tubule epithelial cells
    (The 18th International Forum on Infection and Immunity 2019)
  • Evaluation of a leptospiral enzyme for diagnosis of acute leptospirosis
    (10th International Leptospirosis Society Conference 2017)
  • EibG, a new immunoglobulin-binding protein of LEE-negative, Shiga toxin-producing Escherichia coli, is responsible for the chain-like adhesion phenotype
    (41th Joint Conference on cholera and other bacterial enteric infections 2006)
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Education (2)：
  • 1995 - 1999 University of the Ryukyus
  • 1986 - 1992 Universidad Nacional de Buenos Aires Facultad de Farmacia y Bioquímica Bioquimica
Professional career (1)：
  • PhD (University of the Ryukyus)
Work history (6)：
  • 2017/04 - 現在 琉球大学 大学院医学研究科 細菌学講座 准教授
  • 2007/04/01 - 現在 University of the Ryukyus, Graduate School of Medicine, Research Associate
  • 2007/04 - 2017/03 University of the Ryukyus, Graduate School of Medicine, Research Associate
  • 1994/04 - 1995/03 琉球大学 医学部 細菌学講座 研究生
  • 1993/05 - 1994/03 アルゼンチン国立微生物研究所 研究員
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Awards (2)：
  • 2021/09 - Cellular Microbiology Editor's Choice
  • 2018/01 - 沖縄協会 第39回沖縄研究奨励賞 沖縄で多発する細菌感染症レプトスピラ症に関する研究
Association Membership(s) (2)：
Japanese Society of Tropical Medicine ,  Japanese Society for Bacteriology
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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