Rchr
J-GLOBAL ID:200901088959536000   Update date: Jul. 13, 2020

Nakajima Miki

ナカジマ ミキ | Nakajima Miki
Affiliation and department:
Homepage URL  (1): http://www.p.kanazawa-u.ac.jp/~taisha/index.html
Research field  (5): Pharmacology ,  Pharmaceuticals - health and biochemistry ,  Pharmaceuticals - health and biochemistry ,  Pharmacology ,  Clinical pharmacy
Research keywords  (7): RNA editing ,  microRNA ,  Pharmacokinetics ,  Post-transcriptional regulation ,  genetic polymorphisms ,  interindividual difference ,  Drug metabolism
Research theme for competitive and other funds  (3):
  • Drug Interaction
  • Genetic polymorphism of Drug Metabolizing Enzymes
  • Regulation of drug metabolizing enzymes
Papers (272):
  • Masashi Takizawa, Masataka Nakano, Tatsuki Fukami, Miki Nakajima. Decrease in ADAR1 expression by exposure to cigarette smoke enhances susceptibility to oxidative stress. Toxicology letters. 2020
  • SLC35B1 significantly contributes to the uptake of UDPGA into the endoplasmic reticulum for glucuronidation catalyzed by UDP-glucuronosyltransferase. Biochem Pharmacol. 2020. in press
  • Mai Shimizu, Tatsuki Fukami, Toshio Taniguchi, Yukihiro Nomura, Miki Nakajima. A Novel Systematic Approach for Selection of Prodrugs Designed to Improve Oral Absorption. Journal of Pharmaceutical Sciences. 2020. in press
  • Masataka Nakano, Kyoko Ondo, Seiya Takemoto, Tatsuki Fukami, Miki Nakajima. Methylation of adenosine at the N6 position post-transcriptionally regulates hepatic P450s expression. Biochemical pharmacology. 2020. 171. 113697-113697
  • Masataka Nakano, Kyoko Ondo, Seiya Takemoto, Tatsuki Fukami, Miki Nakajima. m6A modification post-transcriptionally regulates hepatic P450s expression. Biochem Pharmacol. 2019
more...
MISC (41):
  • Fukami Tatsuki, Nakajima Miki. SIGNIFICANCE OF ORPHAN ESTERASES IN CONTROL OF PHARMACOKINETICS AND DRUG TOXICITIES. DRUG METABOLISM AND PHARMACOKINETICS. 2018. 33. 1. S13-S14
  • Miki Nakajima. MicroRNA-RELATED POLYMORPHISMS TO PREDICT DRUG RESPONSE. DRUG METABOLISM REVIEWS. 2015. 47. 28-28
  • 佐々木永太, 飯田あずみ, 常山幸一, 深見達基, 中島美紀, 横井毅. カルバマゼピン誘導性肝障害モデルラットにおける免疫因子を介した発症機序の解明. J Toxicol Sci. 2014. 39. Supplement. S291
  • A. Watanabe, T. Fukami, M. Nakajima, M. Takamiya, Y. Aoki, T. Yokoi. Human Arylacetamide Deacetylase Is a Principal Enzyme in Flutamide Hydrolysis (Vol 37, pg 1513, 2009). DRUG METABOLISM AND DISPOSITION. 2014. 42. 6. 1066-1066
  • 佐々木永太, 常山幸一, 深見達基, 中島美紀, 横井毅. フェニトイン誘導性肝障害マウスの作出と発症メカニズムの解明. J Toxicol Sci. 2013. 38. Supplement. S284
more...
Books (2):
  • Pharmacogenomics and Stratified Medicines
    Elsevir 2014
  • Fifty Years of Cytochrome P450 Research
    Elsevir 2014
Lectures and oral presentations  (27):
  • Regulation of human drug-metabolizing enzymes by two prevalent post-transcriptional modifications, A-to-I editing and methylation of adenosine.
    (2019)
  • Significance of post-transcriptional regulation of drug-metabolizing enzymes: perspective insight into future pharmacotherapy
    (22nd Microsomal and Drug Oxidation/33rd JSSX, Plenary Lecture 2018)
  • microRNA-SNPs as biomarkers of drug response and toxicity.
    (18th Word Congress of Basic and Clinical Pharmacology 2018)
  • Roles of hydrolases and aldehyde oxidase in controlling of pharmacokinetics and drug toxicity
    (日本薬物動態学会第32回年会 2017)
  • Significance of orphan esterases in control of pharmacokinetics and drug toxicities
    (21st North American ISSX Meeting 2017)
more...
Education (3):
  • - 1994 Hokkaido University Graduate School, Division of Pharmaceutical Sciences
  • - 1992 Hokkaido University Faculty of Pharmaceutical Sciences
  • - 1992 Hokkaido University Faculty of Pharmaceutical Science
Work history (7):
  • 2018/04 - 現在 Kanazawa University Professor
  • 2014/03 - 2018/03 Kanazawa University Professor
  • 2009/04 - 2014/02 Kanazawa University Associate Professor
  • 2007/04 - 2009/03 Kanazawa University Associate Professor
  • 2001/08 - 2007/03 Kanazawa University Associate Professor
Show all
Committee career (1):
  • 2002 - -: The Japanese Society for the Study of Xenobiotics
Awards (4):
  • 2009 - DMPK Best Citation Award
  • 2008 - Ebert Prize of the American Pharmacists Association
  • 2007 - Taro Yamshita Award
  • 2005 - Journal of Chromatography Top Cited Article Award
Association Membership(s) (4):
American Society for Pharmacology and Experimental Therapeutics ,  THE JAPANESE SOCIETY OF TOXICOLOGY ,  The Japanese Society of Clinicacl Pharmacology and Therapeutics ,  The Japanese Society for the Study of Xenobiotics
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