Rchr
J-GLOBAL ID:200901089068641372   Update date: Jul. 11, 2020

Hino Jun

ヒノ ジュン | Hino Jun
Homepage URL  (1): http://www.ncvc.go.jp/res/seika/seikaj_01.html
Research field  (5): Metabolism and endocrinology ,  Metabolism and endocrinology ,  Developmental biology ,  Cell biology ,  Molecular biology
Research keywords  (25): fibrosis ,  inflammation ,  insulin resistance ,  hepatitis ,  NAFLD ,  non-alcoholic steatohepatitis ,  NASH ,  endothelial cells ,  cGMP ,  natriuretic peptide ,  CNP ,  C-type natriuretic peptide ,  biologically acitive peptide ,  obesity ,  neural induction ,  osteogenesis ,  endocrinology ,  metabolism ,  adipocyte ,  head formation ,  development embryo ,  TGF-b ,  differentiation ,  growth factor ,  BMP
Research theme for competitive and other funds  (1):
  • 2016 - 2019 Investigation of cardiovascular regulation and multiple function of gastrointestinal peptides
Papers (46):
  • Kentaro Otani, Takeshi Tokudome, Chizuko A Kamiya, Yuanjie Mao, Hirohito Nishimura, Takeshi Hasegawa, Yuji Arai, Mari Kaneko, Go Shioi, Junji Ishida, Akiyoshi Fukamizu, Tsukasa Osaki, Chiaki Nagai-Okatani, Naoto Minamino, Takuya Ensho, Jun Hino, Shunsuke Murata, Misa Takegami, Kunihiro Nishimura, Ichiro Kishimoto, Mikiya Miyazato, Mariko Harada-Shiba, Jun Yoshimatsu, Kazuwa Nakao, Tomoaki Ikeda, Kenji Kangawa. Deficiency of Cardiac Natriuretic Peptide Signaling Promotes Peripartum Cardiomyopathy-Like Remodeling in the Mouse Heart. Circulation. 2020. 141. 7. 571-588
  • Bae CR, HINO J, Hosoda H, Miyazato M, Kangawa K. C-type natriuretic peptide (CNP) in endothelial cells attenuates hepatic fibrosis and inflammation in non-alcoholic steatohepatitis. Life Sciences. 2018. 209. 349-356
  • Bae CR, Hino J, Hosoda H, Son C, Makino H, Tokudome T, Tomita T, Hosoda K, Miyazato M, Kangawa K. Adipocyte-specific expression of C-type natriuretic peptide suppresses lipid metabolism and adipocyte hypertrophy in adipose tissues in mice fed high-fat diet. Scientific reports. 2018. 8. 1. 2093
  • Ogawa Y, Tsuji M, Tanaka E, Miyazato M, Hino J. Bone Morphogenetic Protein (BMP)-3b Gene Depletion Causes High Mortality in a Mouse Model of Neonatal Hypoxic-Ischemic Encephalopathy. Frontiers in neurology. 2018. 9. 397
  • Teranishi H, Hayashi M, Higa R, Mori K, Miyazawa T, Hino J, Amano Y, Tozawa R, Ida T, Hanada T, Miyazato M, Hanada R, Kangawa K, Nakao K. Role of neuromedin U in accelerating of non-alcoholic steatohepatitis in mice. Peptides. 2018. 99. 134-141
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MISC (22):
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Lectures and oral presentations  (3):
  • New role of C-type natriuretic peptide (CNP) in obesity
    (Adiposcience Symposium 2018)
  • New role of C-type natriuretic peptide (CNP) inn obesity and diabetes
    (Japanese Society of Eucommia 2018)
  • BMP-3b inhibits osteoblast differentiation via Smad2/3 pathway by counteracting Smad1/5/8 signaling.
    (2012 International Conference on Bone Morphogenetic Proteins 2012)
Education (1):
  • - 1984 Waseda University School of Science and Engineering
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