Rchr
J-GLOBAL ID：200901089422915590   Update date: Oct. 03, 2024

Inoue Hiroshi

INOUE HIROSHI | Inoue Hiroshi
Affiliation and department：
Kanazawa University Institute for Frontier Science Initiative

About Kanazawa University Institute for Frontier Science Initiative


Other affiliations (1)：
  • 金沢大学  大学院医薬保健学総合研究科   教授
Research field  (3)： Metabolism and endocrinology ,  Nutrition and health science ,  Home economics, lifestyle science
Research keywords  (5)： Integrated Study of Dietary Habits ,  Hepatology ,  Physiology ,  Dietetics ,  Metabolism and endocrinology
Research theme for competitive and other funds  (21)：
  • 2021 - 2024 Discovery and validation of high-performance recombinant ligands
  • 2020 - 2023 生活習慣病における肝糖取り込み制御機構の役割解明
  • 2020 - 2022 代謝変化に伴う迷走神経性炎症制御の解明
  • 2018 - 2020 「生活習慣病の複雑な病態を説明する迷走神経異常の解明」
  • 2014 - 2019 Study of the liver as an endocrine organ
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Papers (87)：
  • Yifei Pan, Atsushi Hatano, Satoshi Ohno, Keigo Morita, Toshiya Kokaji, Yunfan Bai, Hikaru Sugimoto, Riku Egami, Akira Terakawa, Dongzi Li, et al. Time and dose selective glucose metabolism for glucose homeostasis and energy conversion in the liver. npj Systems Biology and Applications. 2024. 10. 1
  • Toshiya Matsukawa, Takashi Yagi, Tohru Uchida, Mashito Sakai, Masaru Mitsushima, Takao Naganuma, Hiroyuki Yano, Yuka Inaba, Hiroshi Inoue, Keisuke Yanagida, et al. Hepatic FASN deficiency differentially affects nonalcoholic fatty liver disease and diabetes in mouse obesity models. JCI insight. 2023. 8. 17
  • Yuka Inaba, Emi Hashiuchi, Hitoshi Watanabe, Kumi Kimura, Yu Oshima, Kohsuke Tsuchiya, Shin Murai, Chiaki Takahashi, Michihiro Matsumoto, Shigetaka Kitajima, et al. The transcription factor ATF3 switches cell death from apoptosis to necroptosis in hepatic steatosis in male mice. Nature Communications. 2023. 14. 1
  • Toshiya Kokaji, Miki Eto, Atsushi Hatano, Katsuyuki Yugi, Keigo Morita, Satoshi Ohno, Masashi Fujii, Ken-ichi Hironaka, Yuki Ito, Riku Egami, et al. In vivo transomic analyses of glucose-responsive metabolism in skeletal muscle reveal core differences between the healthy and obese states. 2022
  • Suguru Fujita, Yasuaki Karasawa, Masashi Fujii, Ken-Ichi Hironaka, Shinsuke Uda, Hiroyuki Kubota, Hiroshi Inoue, Yohei Sumitomo, Akiyoshi Hirayama, Tomoyoshi Soga, et al. Four features of temporal patterns characterize similarity among individuals and molecules by glucose ingestion in humans. NPJ systems biology and applications. 2022. 8. 1. 6-6
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MISC (37)：
  • 小野木 康弘, 和田 努, 神谷 知江, 稲田 健人, 松澤 崇俊, 稲葉 有香, 木村 久美, 井上 啓, 山本 誠士, 石井 陽子, et al. 脂肪血管ペリサイトの動的変化を起点とした脂肪組織肥大化機構の解明. 糖尿病. 2017. 60. Suppl.1. S-137
  • 小野木 康弘, 和田 努, 神谷 知江, 稲田 健人, 稲葉 有香, 木村 久美, 井上 啓, 山本 誠士, 石井 陽子, 恒枝 宏史, et al. PDGFRβは血管リモデリングを介して脂肪組織肥大化とインスリン抵抗性を助長する. 糖尿病. 2016. 59. Suppl.1. S-138
  • Y. Ihara, S. -I. Asahara, H. Inoue, K. Teruyama, T. Matsuda, S. Seino, Y. Kido. Reduction in pancreatic beta cell mass caused by enhanced expression of Cdkn1c via interaction between C/EBP beta and epigenetic control. DIABETOLOGIA. 2014. 57. S177-S177
  • Topics for Pathogenesis of Type 2 Diabetes : Hyper Nutrition ・ Obesity and Chronic Inflammation. 2014. 69. 1. 19-24
  • Hiroshi Inoue. Molecular basis of brain-mediated regulation of hepatic glucose metabolism. Diabetology International. 2014. 5. 3. 158-164
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Patents (3)：
  • 「非アルコール性脂肪性肝疾患及び/又は非アルコール性脂肪性肝炎における肝再生能改善剤」
  • 「肝臓脂肪蓄積抑制剤」
  • 「肝糖産生モニターマウス」
Books (4)：
  • 実験医学増刊;臓器連環による生体恒常性の破綻と疾患
    2019
  • 最新肥満症学;基礎・臨床研究の最前線
    2014
  • 糖尿病の分子標的と治療薬事典
    2013
  • 実験医学増刊;臓器円環による生体恒常性のダイナミクス
    2013
Lectures and oral presentations  (8)：
  • Investigation of a preventive method for non-alcoholic fatty liver disease by food materials
    (The 7th International Conference on Food Factors 2019)
  • Role of GKRP in impeded hepatic glucose uptake in type 2 diabetes
    (ATLAS symposium 2019 Tissue Plasticity of Obesity 2019)
  • NAFLDにおける肝糖取り込み障害のメカニズムと役割
    (第62回日本糖尿病学会年次学術集会 2019)
  • Central insulin action and hepatic glucose metabolism
    (9th Federation of the Asian and Oceanian Pysiological Societies (FAOPS) Congress 2019)
  • Vagal regulation of hepatic glucose metabolism and its disorder
    (第41回日本分子生物学会 2018)
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Education (2)：
  • 1998 - 2001 Kobe University
  • Kobe University School of Medicine Faculty of Medicine
Professional career (1)：
  • 博士(医学) (神戸大学)
Work history (3)：
  • 2015/04 - 現在 Kanazawa University Institute for Frontier Science Initiative
  • 2012/04 - 現在 Kanazawa University
  • 2007/10 - 2012/03 Kanazawa University Frontier Science Organization
Awards (8)：
  • 2018/07 - 日本学術振興会 特別研究員等の審査に係る顕彰
  • 2015/10 - 日本肥満学会 学術奨励賞
  • 2015/04 - 日本内分泌学会 研究奨励賞
  • 2014/11 - 日本医師会 医学研究奨励賞
  • 2014/05 - 日本糖尿病学会 学会賞(リリー賞)
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Association Membership(s) (7)：
THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE JAPANESE BIOCHEMICAL SOCIETY ,  THE JAPAN DIABETES SOCIETY ,  The Japan Endocrine Society ,  JAPAN SOCIETY FOR THE STUDY OF OBESITY ,  JAPAN SOCIETY OF NUTRITION AND FOOD SCIENCE ,  THE PHYSIOLOGICAL SOCIETY OF JAPAN
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