Rchr
J-GLOBAL ID：200901089479368731   Update date: Feb. 01, 2024

Kimura Hideo

キム ラヒデオ | Kimura Hideo
Affiliation and department：
Sanyo-Onoda City University Faculty of Pharmaceutical Science

About Sanyo-Onoda City University Faculty of Pharmaceutical Science


Job title： Professor
Research field  (1)： Basic brain sciences
Research keywords  (13)： TRPA1 ,  MPST ,  polysulfides ,  hydrogen sulfide ,  polysulfide ,  包括脳ネットワーク ,  統合脳・分子脳科学 ,  グリア ,  生理活性物質 ,  硫化水素 ,  ガス ,  シナプス伝達 ,  カルシウム
Research theme for competitive and other funds  (11)：
  • 2016 - 2021 細胞内代謝・ダイナミクス制御から切り拓く発達障害・統合失調症の病理の解明・新規治療法の開発
  • 2017 - 2020 統合失調症生起・転帰の縦断的メカニズムの解明
  • 2017 - 2020 硫化水素およびポリサルファイドの生理機能
  • 2017 - 2018 シグナル分子としての硫化水素とポリサルファイド
  • 2014 - 2017 硫化水素由来ポリサルファイドによるTRPA1チャネル活性化機構の解明
Show all
Papers (159)：
  • Takeo Uba, Yoshiyuki Matsuo, Chisato Sumi, Tomohiro Shoji, Kenichiro Nishi, Munenori Kusunoki, Hiroshi Harada, Hideo Kimura, Hidemasa Bono, Kiichi Hirota. Polysulfide inhibits hypoxia-elicited hypoxia-inducible factor activation in a mitochondria-dependent manner. Mitochondrion. 2021. 59. 255-266
  • Hideo Kimura. Hydrogen Sulfide (H2S) and Polysulfide (H2Sn) Signaling: The First 25 Years. Biomolecules. 2021. 11. 6. 896-896
  • Hideo Kimura. From neurotransmission to neuronal disorders. British Journal of Pharmacology. 2021. 178. 4. 747-749
  • Hideo Kimura. Hydrogen sulfide signalling in the CNS - Comparison with NO. British Journal of Pharmacology. 2020. 177. 22. 5031-5045
  • Hideo Kimura. Signalling by hydrogen sulfide and polysulfides via protein S -sulfuration. British Journal of Pharmacology. 2020. 177. 4. 720-733
ｍore...
MISC (68)：
  • The production and role of hydrogen sulfide and hydrogen polysulfides in mammalian cells. 2017. 70. 9. 117-130
  • Shin Koike, Yuki Ogasawara, Norihiro Shibuya, Kazuyuki Ishii, Hideo Kimura. Polysulfide exerts protective effect against cytotoxicity through Nrf2 signaling in neuronal cells. NITRIC OXIDE-BIOLOGY AND CHEMISTRY. 2014. 39. S39-S39
  • Norihiro Shibuya, Shin Koike, Makiko Tanaka, Mari Ishigami-Yuasa, Yuka Kimura, Yuki Ogasawara, Kiyoshi Fukui, Noriyuki Nagahara, Hideo Kimura. A novel pathway for the production of hydrogen sulfide from D-cysteine in mammalian cells. NITRIC OXIDE-BIOLOGY AND CHEMISTRY. 2014. 39. S26-S26
  • Yuki Ogasawara, Shin Koike, Norihiro Shibuya, Kazuyuki Ishii, Hideo Kimura. Bound sulfur exerts protective effect against cytotoxicity in neuronal cells. NITRIC OXIDE-BIOLOGY AND CHEMISTRY. 2014. 39. S13-S13
  • Yuka Kimura, Yoshinori Mikami, Kimiko Osumi, Mamiko Tsugane, Jun-ichiro Oka, Hideo Kimura. Polysulfides are possible H2S-derived signaling molecules in rat brain. NITRIC OXIDE-BIOLOGY AND CHEMISTRY. 2014. 39. S39-S39
ｍore...
Patents (4)：
  • D-システインを有効成分として含有する硫化水素産生誘導剤
  • アルツハイマー病の予測または診断の方法
  • アルツハイマー病の治療薬または予防薬のスクリーニング法、およびアルツハイマー病を診断する方法、アルツハイマー病発症の危険度を予測する方法
  • タウ遺伝子中の遺伝子多型を利用したアルツハイマー病の発症リスクの予測法およびこれを用いるための核酸分子
Books (8)：
  • Chemistry, Biochemistry and pharmacology of Hydrogen Sulfide.
    Springer Cham Heidelberg New York Dordrecht London. 2015
  • Hydrogen Sulfide and its Therapeutic Applications
    Springer 2013
  • Gasotransmitters: Physiology and Pathophysiology
    Springer 2012
  • Dendritic Neurotransmitter Release.
    Springer 2004
  • Signal transduction and the gasotransmitters: NO, CO, and H2S in Biology and Medicine.
    Humana Press Inc. 2004
ｍore...
Lectures and oral presentations  (59)：
  • Hydrogen sulfide and polysulfides as signaling molecules
    (Pacifichem 2021, ‘Nitric Oxide, Carbon Monoxide and Hydrogen Sulfide as Potential Therapeutic Agents’ 2021)
  • Hydrogen sulfide and polysulfide signaling
    (2021 International Conference on Pharmacological Science, Southern University of Science & Technology (SUSTech) 2021)
  • Involvement of D-Amino Acids in the Production and Function of Hydrogen Sulfide and Polysulfideds
    (The 4th International Conference of D-Amino Acid Reseach (IDAR2019) “D-Amino acids and nervous system” 2019)
  • Hydrogen sulfide (H2S) and Polysulfides (H2Sn) Signaling Through S-sulfuration of Target Proteins
    (Gordon Research Conference “Gasotransmitter Cooperation: Chemistry, Physiology and Pathology” 2019)
  • Hydrogen sulfide (H2S) and polysulfides (H2Sn) signaling through persulfuration of target proteins
    (5th World Congress on Hydrogen Sulfide in Biology and Medicine 2018)
ｍore...
Education (5)：
  • 1985 - University of Tokyo PhD of Pharmaceutical Science
  • 1985 - 東京大学 薬学博士(論文)
  • 1978 - 1980 The University of Tokyo Faculty of Pharmaceutical Sciences
  • 1976 - 1980 University of Tokyo Pharmaceutical Science
  • 1976 - 1978 The University of Tokyo College of Arts and Sciences
Professional career (1)：
  • PhD (Tokyo University)
Work history (9)：
  • 2019/04 - 現在 Tokyo University of Science,Yamaguchi
  • 2017/04 - 2019/03 National Center of Neurology and Psychiatry National Institute of Neuroscience Specially Appointed Researcher
  • 2010/04 - 2017/03 (独)国立精神・神経医療研究センター 神経研究所 神経薬理研究部 部長
  • 1999/05 - 2010/03 国立精神・神経センター 遺伝子工学研究部 部長
  • 1994 - 1999 米国ソーク研究所 分子神経科学 シニアスタッフサイエンティスト
Show all
Awards (13)：
  • 2019/05 - Antioxidants & Redox Signaling Redox Pioneer
  • 2018/11 - Clarivate Analytics Highly Cited Researcher
  • 2018/02 - National Center of Neurology and Psychiatry President Award
  • 2017/11 - Clarivate Analytics Highly Cited Researcher
  • 2016/10 - Thomson Reuter Fourth Research Front Award
Show all
Association Membership(s) (3)：
THE JAPAN NEUROSCIENCE SOCIETY ,  THE JAPANESE BIOCHEMICAL SOCIETY ,  THE JAPANESE PHARMACOLOGICAL SOCIETY
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page

TOP

BOTTOM