Rchr
J-GLOBAL ID:200901089952745521   Update date: Oct. 11, 2024

Ogita Hisakazu

オウギタ ヒサカズ | Ogita Hisakazu
Affiliation and department:
Job title: Professor
Homepage URL  (1): http://www.shiga-med.ac.jp/~hqbioch2/
Research field  (3): Cardiology ,  Medical biochemistry ,  Pathobiochemistry
Research keywords  (2): 細胞接着 ,  シグナル伝達
Research theme for competitive and other funds  (19):
  • 2020 - 2023 老化による心機能低下における低分子量Gタンパク質シグナル伝達系の新たな作用機序
  • 2018 - 2021 Identification of TMEM168 protein mutation in familial Brugada syndrome
  • 2017 - 2020 心血管系におけるペプチド分解酵素DPPIIIの生理学的・病理学的役割と分子機構
  • 2017 - 2020 Novel mechanism for the small G protein-mediated formation and maintenace of vessels
  • 2015 - 2018 Genome-wide analysis to discover the gene mutation that relates to ventricular fibrillation and its molecular mechanism
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Papers (99):
  • Imamura-Uehara Y, Yasuda-Yamahara M, Kuwagata S, Yamahara K, Yoshibayashi M, Tanaka-Sasaki Y, Shimizu A, Ogita H, Chin-Kanasaki M, Kume S. Establishment of a novel mouse model of renal artery coiling-based chronic hypoperfusion-related kidney injury. Biochem Biophys Rep. 2024. 37. 101607
  • Takashima S, Okamura E, Ichiyama Y, Nishi K, Shimizu A, Watanabe C, Muto M, Matsumoto S, Tsukiyama-Fujii S, Tsukiyama T, et al. Null mutation of exocyst complex component 3-like does not affect vascular development in mice. Exp Anim. 2024. 73. 93-100
  • Joanne Ern Chi Soh, Akio Shimizu, Akira Sato, Hisakazu Ogita. Novel cardiovascular protective effects of RhoA signaling and its therapeutic implications. Biochemical Pharmacology. 2023. 218. 115899-115899
  • Sato A, Tsukiyama T, Komeno M, Iwatani C, Tsuchiya H, Kawamoto I, Murase M, Nakagawa T, Itagaki I, Seita Y, et al. Generation of a familial hypercholesterolemia model in non-human primate. Sci Rep. 2023. 13. 15649
  • Nakai S, Tateoka Y, Miyaguchi Y, Takahashi M, Ogita H. Associations between habitual dietary behaviors and glutamic acid levels in human milk. J Hum Lact. 2023. 39. 315-324
more...
MISC (154):
  • 清水昭男, MOLLA Md Rasel, SOH Joanne Ern Chi, 佐藤朗, 扇田久和. 心血管系におけるRhoAの新機能とその分子作用機序. 日本生化学会大会(Web). 2023. 96th
  • 佐藤朗, 扇田久和. 間質細胞との異種細胞間接着によりがん細胞に高発現するストマチンの腫瘍抑制作用. 生化学. 2023. 95. 50-54
  • NGUYEN Le Kim Chil, SHIMIZU Akio, SATO Akira, OGITA Hisakazu. Role of transmembrane protein 168 mutations in Brugada syndrome by alteration in subcellular localization of αB-crystallin to modulate sodium channel Na v1.5 surface expression in cardiomyocytes. 日本生化学会大会(Web). 2022. 95th
  • 佐藤朗, 佐藤朗, 清水昭男, 扇田久和. 非ヒト霊長類モデルを活用したドキソルビシン誘発心筋症における心筋障害因子S100A8/9の同定とその阻害による心保護. 日本腫瘍循環器学会学術集会抄録集(Web). 2022. 5th
  • 扇田久和, 佐藤朗. ストマチンはがん微小環境で発現増加し,Akt経路を抑制してがんの増大を阻止する. 日本癌学会学術総会抄録集(Web). 2021. 80th
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Books (8):
  • モデル動物の作製と利用・循環器疾患2021年上巻
    Life-Science Information Center(エル・アイ・シー) 2021
  • がんの浸潤・転移ー臨床と基礎ー
    南山堂 2011
  • The Sticky Synapse
    Springer 2009
  • がん研究のいま(2. がん細胞の生物学)
    東京大学出版会 2006
  • Methods in Enzymology.
    Academic Press 2006
more...
Lectures and oral presentations  (92):
  • 心血管系におけるRhoAの新機能とその分子作用機序
    (日本生化学会 2023)
  • 最前線研究から見えてくる低分子量Gタンパク質の新機能
    (日本生化学会 2023)
  • The developing embryo requires endothelial RhoA for its angiogenesis and survival
    (日本生化学会近畿支部例会(優秀発表賞受賞) 2023)
  • Employing static electric machine to suppress the progression of diabetic kidney disease by minimizing type 2 diabetes-induced oxidative stress
    (日本生化学会近畿支部例会 2023)
  • Afadin-mediated regulation of vascular smooth muscle cell contraction via the Gq-phospholipase Cβ axis to enhance calcium signaling
    (日本生化学会近畿支部例会(優秀発表賞受賞) 2023)
more...
Education (2):
  • 1999 - 2003 Osaka University Graduate School of Medicine
  • 1989 - 1995 Osaka University Faculty of Medicine Medical School
Professional career (1):
  • MD, PhD (Osaka University)
Work history (8):
  • 2011 - 現在 Shiga University of Medical Science Professor
  • 2019 - 2023 Shiga University of Medical Science Central Research Laboratory
  • 2008 - 2011 Kobe University Graduate School of Medicine Associate Professor
  • 2004 - 2008 Osaka University Graduate School of Medicine Assistant Professor
  • 2003 - 2004 Harvard University Medicine Postdoctoral Fellow
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Awards (6):
  • 2023 - 日本循環器学会国際留学生YIA指導者賞
  • 2022 - 日本循環器学会国際留学生YIA指導者賞
  • 2012 - 日本医師会医学研究奨励賞
  • 2002 - 日本血管細胞生物学会Young Investigator’s Award
  • 2002 - American College of Cardiology, Young Investigator’s Award
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Association Membership(s) (11):
日本医師会 ,  日本血管生物医学会 ,  日本医学教育学会 ,  American Society for Biochemistry and Molecular Biology ,  American Heart Association ,  日本癌学会 ,  日本生化学会 ,  日本心臓病学会 ,  日本循環器学会 ,  日本内科学会 ,  American Society for Cell Biology
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