Research theme for competitive and other funds (6):
HTLV-Iによる発癌機序
E2Fの新しい標的遺伝子の同定
細胞周期制御
Oncogenesis by HTLV-I
Functional analyses of new E2F target genes and distinct transcriptional regulation mediated by E2F
Regulation of the Cell Cycle Progression
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Papers (41):
Kenta Kurayoshi, Masakazu Tanaka, Rinka Nakajima, Yaxuan Zhou, Mashiro Shirasawa, Mariana Fikriyanti, Jun-Ichi Fujisawa, Ritsuko Iwanaga, Andrew P Bradford, Keigo Araki, et al. Utility of Tumor Suppressor E2F Target Gene Promoter Elements to Drive Gene Expression Specifically in Cancer Cells. Cells. 2025. 14. 24
Mashiro Shirasawa, Rinka Nakajima, Yaxuan Zhou, Mariana Fikriyanti, Ritsuko Iwanaga, Andrew P. Bradford, Kenta Kurayoshi, Keigo Araki, Kiyoshi Ohtani. Transcriptional Activation Mechanisms and Target Genes of the Oncogene Product Tax of Human T-Cell Leukemia Virus Type 1. Genes. 2025. 16. 10. 1221-1221
Rinka Nakajima, Yaxuan Zhou, Mashiro Shirasawa, Mariana Fikriyanti, Ritsuko Iwanaga, Andrew P. Bradford, Kenta Kurayoshi, Keigo Araki, Kiyoshi Ohtani. The Transcriptional Coactivator DEAD/H Box 5 (DDX5) Gene Is a Target of the Transcription Factor E2F1 Deregulated from the Tumor Suppressor pRB. Genes. 2025. 16. 8. 929-929
Rinka Nakajima, Yaxuan Zhou, Mashiro Shirasawa, Naoyasu Nishimura, Lin Zhao, Mariana Fikriyanti, Yuki Kamiya, Ritsuko Iwanaga, Andrew P. Bradford, Kaori Shinmyozu, et al. DEAD/H Box 5 (DDX5) Augments E2F1-Induced Cell Death Independent of the Tumor Suppressor p53. International Journal of Molecular Sciences. 2024. 25. 24. 13251-13251
Lin Zhao, Rinka Nakajima, Yaxuan Zhou, Mashiro Shirasawa, Mariana Fikriyanti, Yuki Kamiya, Hiroyuki Toh, Hideyuki Komori, Ritsuko Iwanaga, Andrew P. Bradford, et al. The N-Terminal Region of the Transcription Factor E2F1 Contains a Novel Transactivation Domain and Recruits General Transcription Factor GTF2H2. Biomolecules. 2024. 14. 11. 1357-1357