Rchr
J-GLOBAL ID：200901090134957619   Update date: Feb. 01, 2024

Hosaka Masahiro

ホサカ マサヒロ | Hosaka Masahiro
Affiliation and department：
Akita Prefectural University Division of Molecular and Cellular Biology, Department of Biotechnology

About Akita Prefectural University Division of Molecular and Cellular Biology, Department of Biotechnology


Homepage URL  (1)： http://www.akita-pu.ac.jp/bioresource/dbt/molb/mhosaka/index.html
Research field  (6)： Metabolism and endocrinology ,  Neuroscience - general ,  Functional biochemistry ,  Molecular biology ,  Chemical biology ,  Cell biology
Research keywords  (7)： responses for oxygen in neuro-endocrine cells ,  peptide hormone ,  secretory granule ,  synaptic vesicle ,  bio-imaging ,  hypoxia ,  Endocrine
Research theme for competitive and other funds  (21)：
  • 2020 - 2024 負荷で顕在化するホルモン分泌不全の謎:グラニン蛋白欠損マウスから生活習慣病に迫る
  • 2021 - 2024 ホルモン前駆体と活性化酵素群が出会う仕組み:グラニンを介した共輸送機構の解明
  • 2018 - 2021 内分泌細胞の酸素応答とホルモン生合成・分泌制御のクロストークを解明する
  • 2016 - 2018 イリジウム錯体の特性を活かしNash病巣を描出する新規生体イメージング技法の確立
  • 2014 - 2017 Diversity in the global organization of the Golgi apparatus in differentiated secretory cells.
Show all
Papers (82)：
  • Kubota C., Torii R., Hosaka M., Takeuchi T., Gomi H., Torii S. Phogrin Regulates High-Fat Diet-Induced Compensatory Pancreatic β-Cell Growth by Switching Binding Partners. Nutrients. 2024. 16. 1. 169-169
  • Yasui T, Mashiko M, Obi A, Mori H, Ito-Murata M, Hayakawa H, Kikuchi S, Hosaka M, Kubota C, Torii S, et al. Insulin granule morphology and crinosome formation in mice lacking the pancreatic β cell-specific phogrin (PTPRN2) gene. Histochem Cell Biol. 2023. ahead of print
  • Hiroshi Gomi, Takahiro Nagumo, Kazushi Asano, Makoto Konosu, Tadashi Yasui, Seiji Torii, Masahiro Hosaka. Differential Expression of Secretogranins II and III in Canine Adrenal Chromaffin Cells and Pheochromocytomas. Journal of Histochemistry & Cytochemistry. 2022. 70. 5. 335-356
  • Hiroshi Gomi, Airi Hinata, Tadashi Yasui, Seiji Torii, Masahiro Hosaka. Expression Pattern of the LacZ Reporter in Secretogranin III Gene-trapped Mice. Journal of Histochemistry & Cytochemistry. 2021. 002215542199684-002215542199684
  • Eri Sato, Yoshinori Maeda, Yui Sato, Airi Hinata, Hiroshi Gomi, Daisuke Koga, Seiji Torii, Tsuyoshi Watanabe, Masahiro Hosaka. Culture in 10% O2 enhances the production of active hormones in neuro-endocrine cells by up-regulating the expression of processing enzymes. Biochemical Journal. 2019. 476. 5. 827-842
ｍore...
MISC (40)：
ｍore...
Patents (10)：
  • 含ケイ素置換基を導入した化合物、並びにそれを含む一重項酸素発生剤及び癌治療薬
  • 新規化合物およびそれを含む機能性発光プローブ
  • COMPOUND AND FUNCTIONAL LUMINESCENT PROBE COMPRISING THE SAME(新規化合物およびそれを含む機能性発光プローブ)
  • 新規水溶性イリジウム錯体化合物およびそれを用いた酸素濃度測定試薬
  • 新規錯体化合物、並びにそれを用いた酸素濃度測定試薬および癌の診断薬
ｍore...
Books (3)：
  • 生活習慣病最前線
    上毛新聞社 2012
  • 群馬に多い病気
    上毛新聞社 2007
  • 新時代への視点
    上毛新聞社 2006
Lectures and oral presentations  (18)：
  • Redundancy in sorting systems destined for secretory granules ensure the regulated secretion of peptide hormones.
    (2022)
  • Sorting Mechanisms of Prohormones from the Trans-Golgi Network to Secretory Granules: Concepts with Granin-Family Protein
    (2019)
  • Sorting Mechanisms of Prohormones from the Trans-Golgi Network to Secretory Granules: Concepts with Granin-Family Protein
    (2018)
  • Golgi Apparatus Structures and Function: Sorting Mechanisms of Prohormones from the Trans-Golgi Network to Secretory Granules: Concepts with Granin-Family Protein.
    (Gordon Research Conferences; (New London, U.S.A.) 2014)
  • ホルモンがゴルジ体から分泌顆粒へソーティングされる機構
    (第115回 解剖学会 2010)
ｍore...
Education (3)：
  • 1992 - 1995 Ph.D: University of Tsukuba
  • 1990 - 1992 MS.: University of Tsukuba
  • 1986 - 1990 BS.: University of Tsukuba
Professional career (3)：
  • Ph.D. (University of Tsukuba)
  • M.S. (University of Tsukuba)
  • B.S. (University of Tsukuba)
Work history (7)：
  • 2011/04 - 現在 Akita Prefectural University Faculty of Bioresource Sciences
  • 2004/04 - 2011/03 Gunma University Institute for Molecular and Cellular Regulation
  • 1999/07 - 2004/03 Gunma University Institute for Molecular and Cellular Regulation
  • 1998/04 - 1999/06 University of Texas Southwestern medical Institute at Dallas HHMI resercher
  • 1996/04 - 1998/03 University of Texas HFSP researcher
Show all
Committee career (3)：
  • 2015/07 - 現在 日本生化学会 評議員
  • 2012/06 - 現在 日本生化学会東北支部 評議員
  • 2016 - 2017 日本生化学会 代議員
Awards (5)：
  • 金原一郎記念医学医療振興財団研究助成金
  • 上原記念生命科学財団研究奨励金
  • 中島記念国際交流財団研究助成
  • 日本糖尿病財団研究助成金
  • 病態代謝研究会研究助成金
Association Membership(s) (6)：
Endocrine Society ,  THE JAPANESE BIOCHEMICAL SOCIETY ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  Japanese Society FOR Molecular Imaging ,  JAPAN SOCIETY FOR CELL BIOLOGY ,  日本下垂体研究会
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page

TOP

BOTTOM