Rchr
J-GLOBAL ID：200901090345888729
Update date: Feb. 01, 2024
Nakamura Morihiko
ナカムラ モリヒコ | Nakamura Morihiko
Affiliation and department：
Homepage URL (1)：
http://www.med.shimane-u.ac.jp/CMRC/index2.htm
Research field (4)：
Medical biochemistry
, Molecular biology
, Immunology
, Functional biochemistry
Research keywords (6)：
産学連携学
, ナノバイオ
, ユビキチン
, 免疫生化学
, Ubiquitin
, Immunochemistry
Research theme for competitive and other funds (15)：
- 2020 - 2023 ユビキチン様タンパク質MNSFβの糖代謝制御によるがん細胞増殖調節機構の解明
- 2017 - 2021 Ubiquitin-like protein MNSF is disaggregated and regulates cell proliferation
- 2017 - 2020 ユビキチン様タンパク質MNSFβによる細胞分化の分子制御機構の解明
- 2014 - 2017 ユビキチン様タンパク質MNSFβによる細胞分化の分子制御機構の解明
- 2011 - 2014 Isolation and characterization of ubiquitin-like protein MNSF-conjugating enzymes
- 2007 - 2009 Ubiquitin-like MNSFβ regulates apoptosis
- 2003 - 2005 Characterization of ubiquitin-like polypeptide acceptor protein, a novel pro-apoptotic member of the Bcl-2 family
- 2004 - Study on yeast β-glucan
- 2001 - 2003 Novel mechanism of action of monoclonal nonspecific suppressor factor (MNSF)
- 1996 - 1998 STUDY ON THE MODE OF ACTION OF MONOCLONAL NONSPECIFIC SUPPRESSOR FACTOR (MNSF)
- 1993 - 1994 モノクローナル抗原非特異抑制因子(MNSF)の遺伝子単離とその応用
- 1989 - 1991 抗原非特異抑制因子の構造遺伝子の単離とその応用
- 1987 - 1989 抗原非特異抑制因子に対するモノクローナル抗体の作製とその応用
- Research on the Mechanism of Action of Immunosuppressor
- Study on immune response suppressor factor
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Papers (63)：
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Morihiko Nakamura, Kyoko Yamasaki, Megumi Kono. Ubiquitin-like protein MNSFβ regulates glycolysis and promotes cell proliferation with HSC70 assistance. Biochemistry and Biophysics Reports. 2023. 33. 101414-101414
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Morihiko Nakamura, Yuki Fukuma, Kaori Notsu, Megumi Kono. Quercetin and HSC70 coregulate the anti-inflammatory action of the ubiquitin-like protein MNSFβ. Molecular Biology Reports. 2022. 49. 2. 1213-1222
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Nakamura M, Notsu K, Nakagawa M. Heat shock protein 60 negatively regulates the biological functions of ubiquitin-like protein MNSFβ in macrophages. Molecular and cellular biochemistry. 2019
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Nakamura M, Watanabe N. Subchronic intravenous toxicity study of biofunctional ZnO and its application as a fluorescence probe for cell-specific targeting. Journal of biochemical and molecular toxicology. 2018. 33. 4. e22276
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Kaori Notsu, Mai Nakagawa, Morihiko Nakamura. Ubiquitin-like protein MNSF beta noncovalently binds to molecular chaperone HSPA8 and regulates osteoclastogenesis. MOLECULAR AND CELLULAR BIOCHEMISTRY. 2016. 421. 1-2. 149-156
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MISC (22)：
Patents (4)：
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Fluorescent labeling material and fluorescent labeling agent
-
蛍光標識剤および蛍光標識方法
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水溶性超常磁性ナノ粒子
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蛍光標識材料および蛍光標識剤
Books (12)：
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Immunosuppression by a novel ubiquitin-like molecule
Recent Research Development in Immunology 2001
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Diagnosis of cevebral amyloid angiopathy with cerebral hemorrhage by enzyme-linked immunosorbent assay (ELISA) of cystatin C in cerebrospinal fluid
Plenum Press, New York 1990
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Cerebral amyloid angiopathy associated with cerebral hemorrhage with the deposition of cystatin C : Study on Japanese case
Amyloid and Amyloidosis, kluwer Academic Publishers, london. 1990
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Cystatin C(γ-trace)and β-protein coexist in the cerebral hemorrhage and consequential vascular dementia
Basic, Clinical and Therapeutic Aspects of Alzheimer's and Parkinson's disease, Plenum Press. New York 1990
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Basic,Clinical and Therapeutic Aspects of Alzheimer and Parkinsons Disease" Diagnosis of cerebral amyloid angiopathy with cerebral hemorrhage by enzyme-linked immunosorbent assay (ELISA) of cystatin C in cerebrospinal fluid.
Plenum Press, New York 1990
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Lectures and oral presentations (5)：
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「やさしい医工連携」が秘めた地域創生の可能性
(医工連携シンポジウム 2019)
-
次世代型医療研究
(中央西日本メディカル・イノベーション2018 2019)
-
Ubiquitin-like protein MNSFβis disaggregated and regulates cell proliferation.
(24st International Congress of Biochemistry 2018)
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Ubiquitin-like protein MNSFß binds to proapoptotic Bcl-G and regulates apoptosis in macrophages and T cells.
(Cell symposia: Cell Death and Immunology, Berkeley, USA 2015)
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Ubiquitin-like protein MNSFβ covalently binds to Bcl-G and enhances lipopolysaccharide (LPS)/interferon γ (IFNγ)-induced apoptosis in macrophages
(15th International Congress of Immunology 2013)
Works (1)：
-
Joint Research on the Mechanism of Action of Immuosuppressor
1987 -
Professional career (1)：
- Doctor of Medicine (*Shimane Medical University*)
Work history (10)：
- 2018 - 現在 Shimane University
- 2016/11 - 現在 Shimane University
- 2005 - 2018 Shimane University Collaboration Center Professor
- 2003 - 2005 島根大学 共同研究センター 助教授
- 2002 - 2003 Shimane Medical University
- 2003 - - Shimane University, Associate Professor
- 1990 - 2002 Shimane Medical University
- 1990 - 2002 Shimane Medical University, Research
- 2002 - - Shimane Medical University, Associate Professor
- Assistant
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Committee career (1)：
Awards (1)：
- 2012/12 - 日刊工業新聞社 第7回 モノづくり連携大賞・特別賞
Association Membership(s) (5)：
産学連携学会
, 日本生化学会
, 日本血液学会
, 日本癌学会
, 日本免疫学会
