Rchr
J-GLOBAL ID:200901090373992450   Update date: Apr. 23, 2024

Yuasa Hiroaki

ユアサ ヒロアキ | Yuasa Hiroaki
Affiliation and department:
Job title: Professor
Homepage URL  (2): http://www.phar.nagoya-cu.ac.jp/hp/yzghttp://www.phar.nagoya-cu.ac.jp/hp/yzg/e-index.html
Research field  (1): Clinical pharmacy
Research keywords  (4): drug therapy ,  transporter ,  drug disposition ,  drug development
Research theme for competitive and other funds  (8):
  • 2020 - 2023 新規ポリアミントランスポーターの機能及び生理的役割の解明
  • 2013 - 2016 Nucleobase Transport Function of Aquaporin 10: Its Role in the Intestinal Absorption of Nucleobases and Analogous Drugs
  • 2011 - 2012 Functional Characteristics of a Novel Transporter Specifically Expressed in the Endoplasmic Reticulum in Dendritic Cells and its Role in Immune System
  • 2008 - 2010 Identification and Functional Analysis of the Na^+-Dependent Glycerol Transporter in HCT-15 Cells
  • 2006 - 2007 Molecular and Functional Characteristics of Glycerol Transporter in HCT-15 Cell Model
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Papers (120):
  • Shogo Akino, Tomoya Yasujima, Rei Shibutani, Takahiro Yamashiro, Hiroaki Yuasa. Involvement of Proton-Coupled SLC49A4-Mediated Transport in the Export of Lysosomally Trapped Pyrilamine. Drug Metabolism and Disposition. 2024. 52. 1. 19-25
  • Shogo Akino, Tomoya Yasujima, Takahiro Yamashiro, Hiroaki Yuasa. Disrupted in renal carcinoma 2 (DIRC2/SLC49A4) is an H+-driven lysosomal pyridoxine exporter. Life Science Alliance. 2023. 6. 2. e202201629
  • Kohei Miyake, Tomoya Yasujima, Syunsuke Takahashi, Takahiro Yamashiro, Hiroaki Yuasa. Identification of the amino acid residues involved in the species-dependent differences in the pyridoxine transport function of SLC19A3. Journal of Biological Chemistry. 2022. 298. 8. 102161
  • Takahiro Yamashiro, Tomoya Yasujima, Hiroaki Yuasa. Animal species differences in the pyridoxine transport function of SLC19A3: Absence of Slc19a3-mediated pyridoxine uptake in the rat small intestine. Drug Metabolism and Pharmacokinetics. 2022. 44. 100456
  • Yutaro Shinoda, Takahiro Yamashiro, Akira Hosooka, Tomoya Yasujima, Hiroaki Yuasa. Functional characterization of human organic anion transporter 10 (OAT10/SLC22A13) as an orotate transporter. Drug Metabolism and Pharmacokinetics. 2022. 43. 100443
more...
MISC (14):
Patents (1):
  • 小腸上皮細胞特異的な尿酸トランスポーター及びその利用
Books (5):
  • Drug absorption from the colon in situ
    "Drug Absorption Studies: In Situ, In Vitro and In Silico Models" ed. by Carsten Ehrhardt and Kwang-Jin Kim, Springer, New York, NY, pp. 77 - 88 (Ch. 3) 2008
  • 消化管吸収の評価法
    「分子薬物動態学」,杉山 雄一,楠原 洋之編,南山堂,東京,pp. 447 - 459(第24章) 2008
  • 消化管吸収性の予測:in vitroからin vivoへ
    「薬物バイオアベイラビリティ評価と改善の科学:より良き医薬品開発のために」,杉山 雄一編,現代医療社,東京,pp. 229 - 245(第7章,第1部) 1998
  • 腸管吸収の予測:in vitroからin vivoへ
    「ファーマコキネティクス研究の方法と技術」,日本薬物動態学会ワークショップ実行委員会編,日本薬物動態学会,東京,pp. 169 - 181(第8章) 1993
  • 薬物生体膜輸送のヒトへの外挿
    「続医薬品の開発(第4巻):薬物の生体膜輸送と組織標的化II」,寺田 弘,辻 彰編,廣川書店,東京,pp. 518 - 523(第5章,第8節) 1991
Education (3):
  • 1985 - 1986 The University of Tokyo Graduate School of Pharmaceutical Sciences Ph.D. Course
  • 1983 - 1985 The University of Tokyo Graduate School of Pharmaceutical Sciences M.S. Course (completed)
  • 1979 - 1983 The University of Tokyo Faculty of Pharmaceutical Sciences (completed)
Professional career (1):
  • Ph.D. (The University of Tokyo)
Work history (6):
  • 2002 - 現在 Nagoya City University Graduate School of Pharmaceutical Sciences Professor
  • 2000 - 2002 Nagoya City University Faculty of Pharmaceutical Sciences Professor
  • 1992 - 2000 Nagoya City University Faculty of Pharmaceutical Sciences Associate Professor
  • 1991 - 1992 Nagoya City University Faculty of Pharmaceutical Sciences Senior Assistant Professor
  • 1989 - 1991 The University of Michigan College of Pharmacy Postdoctoral Fellow
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Awards (2):
  • 1995 - Japanese Society for the Study of Xenobiotics Young Investigator Award
  • 1993 - Pharmaceutical Society of Japan (Tokai Chapter) Young Investigator Award
Association Membership(s) (8):
American Society for Pharmacology and Experimental Therapeutics ,  International Society for the Study of Xenobiotics ,  International Pharmaceutical Federation ,  Controlled Release Society ,  American Association of Pharmaceutifical Scientists ,  Academy of Pharmaceutical Science and Technology, Japan ,  Japanese Society for the Study of Xenobiotics ,  Pharmaceutical Society of Japan
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