Rchr
J-GLOBAL ID:200901090410223462
Update date: Jun. 13, 2024
Muramoto Kazumasa
ムラモト カズマサ | Muramoto Kazumasa
Affiliation and department:
Job title:
Associate Professor
Homepage URL (1):
http://www.sci.u-hyogo.ac.jp
Research field (2):
Structural biochemistry
, Biophysics
Research keywords (6):
Bioenergetics
, Cellular respiration
, Respiratory chain
, Cytochrome c oxidase
, Nitric oxide reductase
, X-ray crystallography
Research theme for competitive and other funds (12):
- 2022 - 2023 コール酸フリー新規精製法を用いた呼吸酵素の分子進化による獲得機能の解明
- 2019 - 2023 Structural Dynamics of Nitric Oxide Reductases Srudied by Time-Resolved Techniques
- 2018 - 2021 Structural and functional analysis of the respiratory terminal enzymes
- 2015 - 2018 Structural basis of energy transduction mechanism in the respiratory terminal enzymes.
- 2010 - 2015 Structural and functional analyses of heme-copper oxygen reductases to elucidate the energy transduction mechanism
- 2010 - 2012 Elucidation of the mammalian mitochondrial respiration mechanism at the atomic level.
- 2007 - 2011 ミトコンドリア呼吸の作用機序の全容の解明を目指す高分解能立体構造解析と機能解析
- 2004 - 2009 The atomic mechanism of the functions of protein complexes which drive mitochondrial energy transduction.
- 2004 - 2005 チトクロム酸化酵素エネルギー変換機構のX線構造解析
- 2001 - 2002 X-ray crystallographic analysis of the catalytic intermediate of bovine cytochrome c oxidase
- 2000 - 2001 ウシ心筋チトクロム酸化酵素のX線結晶構造に基づくプロトン輸送経路の解析
- 1999 - 2000 X-ray crystallographic analysis of bovine cytochrome c oxidase with inhibitor complex
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Papers (43):
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Atsuhiro Shimada, Jumpei Baba, Shuhei Nagao, Kyoko Shinzawa-Itoh, Eiki Yamashita, Kazumasa Muramoto, Tomitake Tsukihara, Shinya Yoshikawa. Crystallographic cyanide-probing for cytochrome c oxidase reveals structural bases suggesting that a putative proton transfer H-pathway pumps protons. The Journal of biological chemistry. 2023. 105277-105277
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Kazumasa Muramoto, Kyoko Shinzawa-Itoh. Calcium-bound structure of bovine cytochrome c oxidase. Biochimica et Biophysica Acta (BBA) - Bioenergetics. 2023. 1864. 2. 148956-148956
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Yuya Nishida, Sachiko Yanagisawa, Rikuri Morita, Hideki Shigematsu, Kyoko Shinzawa-Itoh, Hitomi Yuki, Satoshi Ogasawara, Ken Shimuta, Takashi Iwamoto, Chisa Nakabayashi, et al. Identifying antibiotics based on structural differences in the conserved allostery from mitochondrial heme-copper oxidases. Nature Communications. 2022. 13. 1
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Atsuhiro Shimada, Fumiyoshi Hara, Kyoko Shinzawa-Itoh, Nobuko Kanehisa, Eiki Yamashita, Kazumasa Muramoto, Tomitake Tsukihara, Shinya Yoshikawa. Critical roles of the CuB site in efficient proton pumping as revealed by crystal structures of mammalian cytochrome c oxidase catalytic intermediates. Journal of Biological Chemistry. 2021. 297. 3. 100967-100967
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Kyoko Shinzawa-Itoh, Kazumasa Muramoto. Biochemical and crystallographic studies of monomeric and dimeric bovine cytochrome c oxidase. Biophysics and Physicobiology. 2021. 18. 186-195
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MISC (176):
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島田敦広, 原史剛, 江藤勇樹, 伊藤(新澤)恭子, 山下栄樹, 村本和優, 吉川信也, 月原冨武, 月原冨武. チトクロムc酸化酵素の構造多型結晶での反応中間体の構造決定. 日本結晶学会年会講演要旨集. 2022. 2022
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伊藤(新澤)恭子, 青江新平, 島田悟, 馬場淳平, 藤本光輝, 島田敦広, 山下栄樹, 吉川信也, 月原冨武, 月原冨武, et al. Second cytochrome c binding structure of the bovine heart cytochrome c oxidase. 日本生体エネルギー研究会討論会講演要旨集. 2021. 47th (CD-ROM)
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GOPALASINGAM Chai, YAMAOKA Hiroaki, SHIBATA Akitoshi, FUKUMOTO Kouki, SHIGEMATSU Hideki, TOSHA Takehiko, MURAMOTO Kazumasa, SHIRO Yoshitsugu. Probing functional and structural differences of quinol dependent Nitric Oxide Reductases’ (qNOR) within a lipidic nanodisc environment. 日本蛋白質科学会年会プログラム・要旨集. 2021. 21st
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BIN MOHAMAD JAMALI Muhamad Arif, GOPALASINGAM Chai C., JOHNSON Rachel M., MUENCH Stephen P, ANTONYUK Svetlana V., HASNAIN Samar S., TOSHA Takehiko, MURAMOTO Kazumasa, SHIRO Yoshitsugu. Cryo-EM, Crystallographic And Kinetic Study Of Quinol-dependent Nitric Oxide Reductases From Neisseria Meninigitidis. 日本蛋白質科学会年会プログラム・要旨集. 2020. 20th (Web)
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SHINZAWA-ITOH Kyoko, HATANAKA Miki, FUJITA Kazuya, YANO Naomine, OGASAWARA Yumi, IWATA Jun, YAMASHITA Eiki, TSUKIHARA Tomitake, TSUKIHARA Tomitake, YOSHIKAWA Shinya, et al. The 1.3 Å resolution structure of bovine mitochondrial respiratory oxygen reductase suggests a dimerization mechanism. 生物物理(Web). 2020. 60. Supplement 1-2
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Books (1):
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「構造情報に基づくミトコンドリア呼吸鎖複合体の反応機構及び活性制御メカニズム」 ミトコンドリアダイナミクス : 機能研究から疾患・老化まで
エヌ・ティー・エス 2021 ISBN:9784860437466
Lectures and oral presentations (229):
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ウシ心筋シトクロム酸化酵素のカルシウム結合構造
(日本生体エネルギー研究会第49回討論会 2023)
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ウシ心筋シトクロム酸化酵素のカルシウム結合構造
(日本生物物理学会第61回年会 2023)
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シトクロム酸化酵素における金属中心の酸化状態変化によって駆動されるプロトン輸送機構の解明
(第23回日本蛋白質科学会年会 2023)
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シアン化物結合シトクロム酸化酵素の結晶構造から示唆される、金属中心の酸化状態変化による活性制御
(日本生物物理学会第60回年会 2022)
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XFELを用いた時分割構造解析によって期待される, シトクロム酸化酵素の反応機構解明
(第48回生体分子科学討論会 2022)
more...
Education (2):
- 1990 - 1995 Nagoya University Graduate School of Science
- 1986 - 1990 Nagoya University School of Science Department of Physics
Professional career (1):
- Doctor(Science) (Nagoya University)
Work history (3):
- 2003 - 現在 University of Hyogo of Science, Graduate School
- 1998 - 2003 Himeji Institute of Technology
- 1995 - 1998 Yale University Departmenyt of Molecular Biophysics and Biochemistry
Awards (1):
Association Membership(s) (2):
日本蛋白質科学会
, The Biophysical Society of Japan
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