Unno Hideaki

ウンノヒデアキ | Unno Hideaki

Affiliation and department：
Homepage URL (1)： http://www.cms.nagasaki-u.ac.jp/lab/seitai/

Research field (2)： Applied biochemistry , Structural biochemistry

Research keywords (7)：構造生物学 , 海産無脊椎動物 , 酵素 , Transporter , Lectin , X線結晶構造解析 , Protein Crystallography

Research theme for competitive and other funds (16)：

2022 - 2025 AMPDの結晶構造解析による反応機構の解明
2020 - 2023 Creation of microbial cells as the innovative chassis for isoprenoid production
2017 - 2020 Elucidation of novel functions of marine invertebrate lectins based on their structural diversity and its application
2015 - 2018 structural and functional analyses of novel lectins from marine invertebrates, and its application.
2014 - 2017 Development of EGFR-Tyrosine Kinase Inhibitors Effective for Non-Small Cell Lung Cancer Resistant to Gefitinib

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Papers (56)：

Tomomitsu Hatakeyama, Fuki Kojima, Issei Ohkawachi, Hitomi Sawai, Hideaki Unno. Carbohydrate-binding ability of a recombinant protein containing the DM9 motif from Drosophila melanogaster. The Journal of Biochemistry. 2024
Tomomitsu Hatakeyama, Hideaki Unno. Functional Diversity of Novel Lectins with Unique Structural Features in Marine Animals. Cells. 2023. 12. 14. 1814-1814
Tomomitsu Hatakeyama, Akihiro Kishigawa, Hideaki Unno. Molecular cloning and characterization of the two putative toxins expressed in the venom of the devil stinger Inimicus japonicus. Toxicon. 2021. 201. 9-20
Miyako Okada, Hideaki Unno, Koh-Ichi Emi, Mayuko Matsumoto, Hisashi Hemmi. A versatile cis-prenyltransferase from Methanosarcina mazei catalyzes both C- and O-prenylations. Journal of Biological Chemistry. 2021. 296. 100679-100679
Kayo Imamura, Takanori Matsuura, Atsushi Nakagawa, Shinichi Kitamura, Masami Kusunoki, Takeshi Takaha, Hideaki Unno. Structural analysis and reaction mechanism of the disproportionating enzyme (D-enzyme) from potato. Protein science : a publication of the Protein Society. 2020. 29. 10. 2085-2100

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MISC (13)：

海野英昭. 無脊椎動物由来溶血性レクチンの細胞膜孔形成機構 CEL-IIIによる膜孔形成メカニズム. 化学と生物. 2015. 53. 2. 74-75
邊見久, 長井拓也, 海野英昭, 吉村徹. 1-IV-3 不可逆阻害剤となる基質アナログを用いたタイプ2イソペンテニル二リン酸イソメラーゼの反応機構解析(一般演題要旨,日本ビタミン学会第63回大会講演要旨). ビタミン. 2011. 85. 4. 226-226
Hideaki Unno, Tomomitsu Hatakeyama, Takuro Kamiya, Masami Kusunoki, Sachiko Nakamura-Tsuruta, Jun Hirabayashi, Shuichiro Goda. Crystal structure of CEL-IV, isolated from a sea cucumber, cucumaria echinata. ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES. 2011. 67. C547-C547
海野英昭. C. echinata由来溶血性レクチンCEL-IIIの膜孔形成複合体結晶構造解析. 研究助成金受給者研究報告集. 2011. 30. 63-67
邊見久, 長井拓也, 海野英昭, 吉村徹. 1-III-4 タイプ2イソペンテニル二リン酸イソメラーゼの反応における還元型FMNの分子触媒機構(一般演題,日本ビタミン学会第62回大会発表要旨). ビタミン. 2010. 84. 4. 164-164

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Books (3)：

Lectin Purification and Analysis : Methods and Protocols (Methods in Molecular Biology (2132))
Springer US 2020
Flavins and Flavoproteins 2011
Lulu.com 2013
構造生物学 -ポストゲノム時代のタンパク質研究-
共立出版 2007

Lectures and oral presentations (4)：

Education (1)：

Professional career (1)：

Work history (7)：

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Association Membership(s) (3)：

THE JAPANESE BIOCHEMICAL SOCIETY , PROTEIN SCIENCE SOCIETY OF JAPAN , THE CRYSTALLOGRAPHIC SOCIETY OF JAPAN

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