Rchr
J-GLOBAL ID：200901091404718715   Update date: Mar. 23, 2024

Hashimoto Kenji

Hashimoto Kenji
Affiliation and department：
Chiba University

About Chiba University


Job title： Chiba University
Homepage URL  (1)： http://www.m.chiba-u.ac.jp/class/shakai/index2f.htm
Research field  (4)： Nutrition and health science ,  Pharmacology ,  Neuroscience - general ,  Psychiatry
Research keywords  (6)： brain spleen axis ,  brain liver axis ,  brain gut axis ,  R-ketamine ,  ketamine ,  rapid-acting antidepressant
Research theme for competitive and other funds  (29)：
  • 2021 - 2026 思春期の抑うつ・双極性障害傾向とADHDとの併存の問題に関する発達心理学的研究
  • 2021 - 2024 Study of molecular mechanisms underlying antidepressant actions of (R)-ketamine
  • 2021 - 2023 Study of stress-related psychiatric disorders based on brain-gut axis via vagus nerve
  • 2021 - 2023 Constructive understanding of stress-related psychiatric disorders by brain-gut-microbiota axis
  • 2018 - 2022 Problem of coexisting bipolarity and ADHD in childhood and adolescence
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Papers (569)：
  • Yukihiko Shirayama, Masaaki Iwata, Kanako Miyano, Yuki Hirose, Yasunori Oda, Yuko Fujita, Kenji Hashimoto. Infusions of beta-hydroxybutyrate, an endogenous NLRP3 inflammasome inhibitor, produce antidepressant-like effects on learned helplessness rats through BDNF-TrkB signaling and AMPA receptor activation, and strengthen learning ability. Brain research. 2023. 148567-148567
  • Xingming Wang, Akifumi Eguchi, Yong Yang, Lijia Chang, Xiayun Wan, Jiajing Shan, Youge Qu, Li Ma, Chisato Mori, Jianjun Yang, et al. Key role of the gut-microbiota-brain axis via the subdiaphragmatic vagus nerve in demyelination of the cuprizone-treated mouse brain. Neurobiology of Disease. 2023. 176
  • Tsuyoshi Sasaki, Kenji Hashimoto, Tomihisa Niitsu, Yutaka Hosoda, Yasunori Oda, Yuki Shiko, Yoshihito Ozawa, Yohei Kawasaki, Nobuhisa Kanahara, Akihiro Shiina, et al. Ifenprodil tartrate treatment of adolescents with post-traumatic stress disorder: a double-blind, placebo-controlled trial. Psychiatry Research. 2022. 114486-114486
  • Yukihiko Shirayama, Masaaki Iwata, Yuko Fujita, Yasunori Oda, Kenji Hashimoto. The Toll-like receptor 4 antagonist TAK-242 induces antidepressant-like effects in a rat learned helplessness model of depression through BDNF-TrkB signaling and AMPA receptor activation. Behavioural brain research. 2022. 113769-113769
  • Li Ma, Jiancheng Zhang, Yuko Fujita, Youge Qu, Jiajing Shan, Xiayun Wan, Xingming Wang, Tamaki Ishima, Kenta Kobayashi, Long Wang, et al. Nuclear factor of activated T cells 4 in the prefrontal cortex is required for prophylactic actions of (R)-ketamine. Translational psychiatry. 2022. 12. 1. 27-27
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MISC (366)：
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Professional career (1)：
  • 博士(薬学) (九州大学)
Work history (7)：
  • 2005/04 - 現在 Chiba University Center for Forensic Mental Health Professor
  • 2003/03 - 2005/03 Chiba University Graduate School of Medicine
  • 2001/07 - 2003/02 Chiba University Graduate School of Medicine
  • 1993/10 - 1996/08 Japan Science and Technology Agency National Center of Neurology and Psychiatry Visiting fellow
  • 1991/09 - 1993/09 National Institute of Health National Institute on Drug Abuse Visiting Fellow
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Committee career (6)：
  • 2018 - 現在 Psychopharmacology Principal Editor
  • 2015 - 現在 Eur Arch Psychiatry Clin Neurosci Editor
  • 2007 - 現在 PLOS ONE Academic Editor and Section Editor
  • 2017/09 - 2021/06 日本生物学的精神医学会誌 編集長
  • 2017 - 2021 日本生物学的精神医学会 理事
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Awards (2)：
  • 2010/11 - 千葉大学 平成22年度優秀発明特別賞
  • 2004/05 - 千葉大学 ゐのはな同窓会学術賞
Association Membership(s) (9)：
SIRS ,  SOBP ,  CINP ,  Society for Neuroscience ,  ACNP ,  JAPANESE MEDICAL SOCIETY OF ALCOHOL AND ADDICTION STUDIES ,  JAPAN BRAIN SCIENCE SOCIETY ,  JAPANESE SOCIETY OF BIOLOGICAL PSYCHIATRY ,  THE JAPANESE SOCIETY OF NEUROPSYCHOPHARMACOLOGY
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