Rchr
J-GLOBAL ID：200901092022305212   Update date: Jul. 16, 2024

Hamada Hiroki

ハマダ ヒロキ | Hamada Hiroki
Affiliation and department：
Okayama University of Science Faculty of Science, Department of Life Science

About Okayama University of Science Faculty of Science, Department of Life Science


Job title： Professor
Homepage URL  (1)： http://www.ous.ac.jp/DAS/chem/hamada/index.htm
Research field  (1)： Molecular biochemistry
Research keywords  (11)： 脳内薬物デリバリー ,  血液脳関門透過型薬剤の開発 ,  腫瘍集積性をもつ癌治療薬開発 ,  ナノマテリアル ,  オリゴ糖型・機能性素材 ,  物質創成科学 ,  創薬化学 ,  イムノリポソーム ,  ドラッグデリバリーシステム ,  生物有機化学 ,  Bioorganic Chemistry
Research theme for competitive and other funds  (14)：
  • 2018 - 2021 Development of a New Evaluation Method for Exercise Training Using Mitochondrial Activation of Peripheral Blood Mononuclear Cells
  • 2018 - 2021 Biological effect and preventive method for human serum albumin binding to transboundary air borne PM2.5.
  • 2015 - 2018 Glycosylation using plant enzymes to produce anti-histamine agent
  • 2015 - 2018 development of a new remedy for muscular dystrophies
  • 2013 - 2017 Development of the strategy for fundamental therapy of cancer using iPS derived Cancer Stem cell models
Show all
Papers (81)：
  • Hiroki Hamada, Kohji Ishihara, Kei Shimoda, Atsuhito Kuboki, Yuya Kiriake, Ryusuke Hosoda, Noriyuki Uchida. Enzymatic Synthesis of Resveratrol Oligosaccharides (Gluco-oligosaccharides) and their Enhanced Application as Antidementia Drugs that Cross the Blood-brain Barrier (BBB). International Journal of Current Microbiology and Applied Sciences. 2022. 11. 7. 260-266
  • Noriyuki Uchida, Masayoshi Yanagi, Hiroki Hamada. Bicelle Composed of 1,2-Dipalmitoyl-sn-Glycero-3-Phosphatidylcholine and Sodium Cholate. NATURAL PRODUCT COMMUNICATIONS. 2022. 17. 4
  • Hiroki Hamada, Hatsuyuki Hamada, Kohji Ishihara, Atsuhito Kuboki, Takafumi Iwaki, Yuya Kiriake. Enzymatic Synthesis of alpha-Tocopherol Derivative Glycoside, Daidzein Glycoside, Daidzein Oligosaccharide, Resveratrol Oligosaccharide, and Curcumin Oligosaccharides and Their Anti-Allergic Activity and Neuroprotective Activity. NATURAL PRODUCT COMMUNICATIONS. 2021. 16. 10
  • Hiroki Hamada, Hatsuyuki Hamada, Kei Shimoda, Tadakatsu Mandai, Kohji Ishihara, Yuya Kiriake, Atsuhito Kuboki. Synthesis of Ester-Linked Paclitaxel-Glycoside Conjugate as a Water-Soluble Paclitaxel Derivative-Maltoside Modification of Paclitaxel through Ester-Linker (Ester-Spacer). NATURAL PRODUCT COMMUNICATIONS. 2021. 16. 9. 1-3
  • Hiroki Hamada, Hatsuyuki Hamada, Kei Shimoda, Atsuhito Kuboki, Takafumi Iwaki, Yuya Kiriake, Kohji Ishihara. Resveratrol Oligosaccharides (Gluco-Oligosaccharides) Effectively Inhibit SARS-CoV-2 Infection: Glycoside (Polysaccharide) Approach for Treatment of COVID-19. NATURAL PRODUCT COMMUNICATIONS. 2021. 16. 5
ｍore...
MISC (28)：
  • 細田 隆介, 久野 篤史, 瀬堀 理生, 濱田 博喜, 堀尾 嘉幸. ピセアタンノールとレスベラトロールの酸化ストレスに対する細胞保護効果の比較. 日本生化学会大会・日本分子生物学会年会合同大会講演要旨集. 2015. 88回・38回. [3P0135]-[3P0135]
  • Tsukasa Shigehiro, Tomonari Kasai, Akifumi Mizutani, Hiroshi Murakami, Katsuhiko Mikuni, Tadakatsu Mandai, Hiroki Hamada, Masaharu Seno. Anti-cancer activity of immunoliposomes encapsulated effective amount of glycosylated paclitaxel with novel loading strategy. CANCER RESEARCH. 2014. 74. 19
  • Tsukasa Shigehiro, Tomonari Kasai, Akifumi Mizutani, Hiroshi Murakami, Katsuhiko Mikuni, Tadakatsu Mandai, Hiroki Hamada, Masaharu Seno. A novel remote loading method with solubility gradient to encapsulate effevtive amount of taxanes into liposomes. CANCER RESEARCH. 2013. 73. 8
  • Masaharu Murakami, Tomonari Kasai, Masashi Okada, Katsuhiko Mikuni, Naoyoshi Egashira, Masaharu Seno, Hiroki Hamada. Preparation and evaluation of glycosylated paclitaxel loaded in tastuzumab-immunoliposome. CANCER RESEARCH. 2012. 72
  • Noriyoshi "Masuoka, Da-Hong Wang, Michiko Kogashiwa, Koichi Miyashita, Terumasa Nakaie, Kohji Ishihara, Hiroki" Hamada. The effect of juice made from Pione grape-skin extract. 2007. 43. 33-39
ｍore...
Patents (5)：
  • タキソイドの配糖化誘導体およびその製造方法
  • タキソイド誘導体およびその製造法
  • 癌治療用薬剤及びその作製方法
  • タキサン化合物を内包するリポソーム
  • パクリタキセルモノグリコシド及び/又はドタキセルモノグリコシドを内包するリポソームの製造方法
Works (2)：
  • Asymetric reduction by living cell
    1999 - 2000
  • Metabolism of a new medicine
    1999 - 2000
Education (3)：
  • - 1981 Hiroshima University
  • - 1981 Hiroshima University Graduate School, Division of Natural Science
  • - 1979 Okayama University of Science Faculty of Science
Professional career (2)：
  • (BLANK)
  • (BLANK)
Committee career (1)：
  • 1996 - 日本植物細胞分子生物学会 評議員
Awards (4)：
  • 2011/09 - 日本植物細胞分子生物学会 技術賞
  • 2010/07 - 内山勇三科学技術賞
  • 2006/06 - 中国地域産学官コラボレーションセンター 大学発ベンチャー功労賞
  • 1996/05 - 有機合成化学協会 中国四国支部奨励賞
Association Membership(s) (6)：
日本植物細胞分子生物学会 ,  日本生化学会 ,  アメリカ植物生理学会 ,  アメリカ化学会 ,  日本農芸化学会 ,  日本化学会
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