Rchr
J-GLOBAL ID:200901092022305212   Update date: Jul. 16, 2024

Hamada Hiroki

ハマダ ヒロキ | Hamada Hiroki
Affiliation and department:
Job title: Professor
Homepage URL  (1): http://www.ous.ac.jp/DAS/chem/hamada/index.htm
Research field  (1): Molecular biochemistry
Research keywords  (11): 脳内薬物デリバリー ,  血液脳関門透過型薬剤の開発 ,  腫瘍集積性をもつ癌治療薬開発 ,  ナノマテリアル ,  オリゴ糖型・機能性素材 ,  物質創成科学 ,  創薬化学 ,  イムノリポソーム ,  ドラッグデリバリーシステム ,  生物有機化学 ,  Bioorganic Chemistry
Research theme for competitive and other funds  (14):
  • 2018 - 2021 Development of a New Evaluation Method for Exercise Training Using Mitochondrial Activation of Peripheral Blood Mononuclear Cells
  • 2018 - 2021 Biological effect and preventive method for human serum albumin binding to transboundary air borne PM2.5.
  • 2015 - 2018 Glycosylation using plant enzymes to produce anti-histamine agent
  • 2015 - 2018 development of a new remedy for muscular dystrophies
  • 2013 - 2017 Development of the strategy for fundamental therapy of cancer using iPS derived Cancer Stem cell models
Show all
Papers (81):
  • Hiroki Hamada, Kohji Ishihara, Kei Shimoda, Atsuhito Kuboki, Yuya Kiriake, Ryusuke Hosoda, Noriyuki Uchida. Enzymatic Synthesis of Resveratrol Oligosaccharides (Gluco-oligosaccharides) and their Enhanced Application as Antidementia Drugs that Cross the Blood-brain Barrier (BBB). International Journal of Current Microbiology and Applied Sciences. 2022. 11. 7. 260-266
  • Noriyuki Uchida, Masayoshi Yanagi, Hiroki Hamada. Bicelle Composed of 1,2-Dipalmitoyl-sn-Glycero-3-Phosphatidylcholine and Sodium Cholate. NATURAL PRODUCT COMMUNICATIONS. 2022. 17. 4
  • Hiroki Hamada, Hatsuyuki Hamada, Kohji Ishihara, Atsuhito Kuboki, Takafumi Iwaki, Yuya Kiriake. Enzymatic Synthesis of alpha-Tocopherol Derivative Glycoside, Daidzein Glycoside, Daidzein Oligosaccharide, Resveratrol Oligosaccharide, and Curcumin Oligosaccharides and Their Anti-Allergic Activity and Neuroprotective Activity. NATURAL PRODUCT COMMUNICATIONS. 2021. 16. 10
  • Hiroki Hamada, Hatsuyuki Hamada, Kei Shimoda, Tadakatsu Mandai, Kohji Ishihara, Yuya Kiriake, Atsuhito Kuboki. Synthesis of Ester-Linked Paclitaxel-Glycoside Conjugate as a Water-Soluble Paclitaxel Derivative-Maltoside Modification of Paclitaxel through Ester-Linker (Ester-Spacer). NATURAL PRODUCT COMMUNICATIONS. 2021. 16. 9. 1-3
  • Hiroki Hamada, Hatsuyuki Hamada, Kei Shimoda, Atsuhito Kuboki, Takafumi Iwaki, Yuya Kiriake, Kohji Ishihara. Resveratrol Oligosaccharides (Gluco-Oligosaccharides) Effectively Inhibit SARS-CoV-2 Infection: Glycoside (Polysaccharide) Approach for Treatment of COVID-19. NATURAL PRODUCT COMMUNICATIONS. 2021. 16. 5
more...
MISC (28):
  • 細田 隆介, 久野 篤史, 瀬堀 理生, 濱田 博喜, 堀尾 嘉幸. ピセアタンノールとレスベラトロールの酸化ストレスに対する細胞保護効果の比較. 日本生化学会大会・日本分子生物学会年会合同大会講演要旨集. 2015. 88回・38回. [3P0135]-[3P0135]
  • Tsukasa Shigehiro, Tomonari Kasai, Akifumi Mizutani, Hiroshi Murakami, Katsuhiko Mikuni, Tadakatsu Mandai, Hiroki Hamada, Masaharu Seno. Anti-cancer activity of immunoliposomes encapsulated effective amount of glycosylated paclitaxel with novel loading strategy. CANCER RESEARCH. 2014. 74. 19
  • Tsukasa Shigehiro, Tomonari Kasai, Akifumi Mizutani, Hiroshi Murakami, Katsuhiko Mikuni, Tadakatsu Mandai, Hiroki Hamada, Masaharu Seno. A novel remote loading method with solubility gradient to encapsulate effevtive amount of taxanes into liposomes. CANCER RESEARCH. 2013. 73. 8
  • Masaharu Murakami, Tomonari Kasai, Masashi Okada, Katsuhiko Mikuni, Naoyoshi Egashira, Masaharu Seno, Hiroki Hamada. Preparation and evaluation of glycosylated paclitaxel loaded in tastuzumab-immunoliposome. CANCER RESEARCH. 2012. 72
  • Noriyoshi "Masuoka, Da-Hong Wang, Michiko Kogashiwa, Koichi Miyashita, Terumasa Nakaie, Kohji Ishihara, Hiroki" Hamada. The effect of juice made from Pione grape-skin extract. 2007. 43. 33-39
more...
Patents (5):
  • タキソイドの配糖化誘導体およびその製造方法
  • タキソイド誘導体およびその製造法
  • 癌治療用薬剤及びその作製方法
  • タキサン化合物を内包するリポソーム
  • パクリタキセルモノグリコシド及び/又はドタキセルモノグリコシドを内包するリポソームの製造方法
Works (2):
  • Asymetric reduction by living cell
    1999 - 2000
  • Metabolism of a new medicine
    1999 - 2000
Education (3):
  • - 1981 Hiroshima University
  • - 1981 Hiroshima University Graduate School, Division of Natural Science
  • - 1979 Okayama University of Science Faculty of Science
Professional career (2):
  • (BLANK)
  • (BLANK)
Committee career (1):
  • 1996 - 日本植物細胞分子生物学会 評議員
Awards (4):
  • 2011/09 - 日本植物細胞分子生物学会 技術賞
  • 2010/07 - 内山勇三科学技術賞
  • 2006/06 - 中国地域産学官コラボレーションセンター 大学発ベンチャー功労賞
  • 1996/05 - 有機合成化学協会 中国四国支部奨励賞
Association Membership(s) (6):
日本植物細胞分子生物学会 ,  日本生化学会 ,  アメリカ植物生理学会 ,  アメリカ化学会 ,  日本農芸化学会 ,  日本化学会
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