Rchr
J-GLOBAL ID：200901092726320810   Update date: Nov. 12, 2024

Nakamichi Yuko

ナカミチ ユウコ | Nakamichi Yuko
Affiliation and department：
Matsumoto Dental University Institute for Oral Science, Division of Hard Tissue Research

About Matsumoto Dental University Institute for Oral Science, Division of Hard Tissue Research


Job title： Associate Professor
Other affiliations (1)：
  • Washington University in St. Louis  Division of Biology & Biomedical Sciences   Visiting Scholar
Research field  (3)： Oral medicine ,  Functional biochemistry ,  Laboratory animal science
Research keywords  (9)： Vitamin D ,  Osteoblast ,  Wnt ,  ビタミンD ,  骨芽細胞 ,  骨代謝 ,  破骨細胞 ,  Bone remodeling ,  Osteoclast
Research theme for competitive and other funds  (53)：
  • 2024 - 2028 Identification of factors responsible for Ca and P metabolic disease-associated frail-like phenotypes regulated by VDR in osteoblasts
  • 2024 - 2027 Role of CSF-1R Ligand IL-34 in Immune Defense and Healing in Periodontal Tissue
  • 2023 - 2026 Identification of a calcium paradox factor through transcriptomic and secretomic analysis of osteoblasts
  • 2022 - 2026 細胞種特異的老化モデル創出による老化細胞除去機構の解明と抗フレイル戦略の開拓
  • 2022 - 2025 Elucidation of the mechanism of action of Siglec-15 antibody drugs in the treatment of secondary osteoporosis during growth and development
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Papers (63)：
  • Hotsuna Ninomiya, Shinji Fukuda, Hisayo Nishida-Fukuda, Yuto Shibata, Takuma Sato, Yuko Nakamichi, Midori Nakamura, Nobuyuki Udagawa, Ken Miyazawa, Takahiro Suzuki. Osteoprotegerin secretion and its inhibition by RANKL in osteoblastic cells visualized using bioluminescence imaging. Bone. 2024. 117319-117319
  • Tohru Hosoyama, Minako Kawai-Takaishi, Hiroki Iida, Yoko Yamamoto, Yuko Nakamichi, Tsuyoshi Watanabe, Marie Takemura, Shigeaki Kato, Akiyoshi Uezumi, Yasumoto Matsui. Lack of vitamin D signalling in mesenchymal progenitors causes fatty infiltration in muscle. Journal of cachexia, sarcopenia and muscle. 2024
  • Yuko Nakamichi, Ziyang Liu, Tomoki Mori, Zhifeng He, Hisataka Yasuda, Naoyuki Takahashi, Nobuyuki Udagawa. The vitamin D receptor in osteoblastic cells but not secreted parathyroid hormone is crucial for soft tissue calcification induced by the proresorptive activity of 1,25(OH)2D3. The Journal of steroid biochemistry and molecular biology. 2023. 232. 106351-106351
  • Takafumi Mizuno, Tohru Hosoyama, Makiko Tomida, Yoko Yamamoto, Yuko Nakamichi, Shigeaki Kato, Minako Kawai-Takaishi, Shinya Ishizuka, Yukiko Nishita, Chikako Tange, et al. Influence of vitamin D on sarcopenia pathophysiology: A longitudinal study in humans and basic research in knockout mice. Journal of cachexia, sarcopenia and muscle. 2022. 13. 6. 2961-2973
  • 何 治鋒, 溝口 利英, 平賀 徹, 中道 裕子, 山下 照仁, 小出 雅則, 宇田川 信之, 小林 泰浩. マクロファージはLepR陽性細胞を活性化し骨再生を促進する(Macrophages promote bone regeneration through the activation of LepR(+) cells). Journal of Oral Biosciences Supplement. 2022. 2022. 166-166
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MISC (43)：
  • 中道 裕子, 劉 子洋, 何 治鋒, 高橋 直之, 宇田川 信之. 活性型ビタミンDの骨吸収促進作用による軟組織の石灰化に、副甲状腺ホルモンは関与せず、骨芽細胞内のビタミンD受容体が決定的な役割を果たす. Journal of Oral Biosciences Supplement. 2023. 2023. [O3-05]
  • 二宮 秀菜, 福田 信治, 福田 尚代, 佐藤 琢麻, 中村 美どり, 中道 裕子, 宇田川 信之, 宮澤 健, 鈴木 崇弘. RANKL依存的なプロテアソームによるオステオプロテゲリン分泌制御の生物発光分析. Journal of Oral Biosciences Supplement. 2023. 2023. [P2-04]
  • 中道 裕子, 劉 子洋, 何 治鋒, 保田 尚孝, 高橋 直之, 宇田川 信之. 活性型ビタミンDの骨吸収促進作用による軟組織の石灰化に、副甲状腺ホルモンは関与せず、骨芽細胞内のビタミンD受容体が決定的な役割を果たす. 日本骨代謝学会学術集会プログラム抄録集. 2023. 41回. 144-144
  • 二宮秀菜, 福田信治, 福田尚代, 佐藤琢麻, 中村美どり, 中道裕子, 宇田川信之, 宮澤健, 鈴木崇弘. RANKL依存的なプロテアソームによるオステオプロテゲリン分泌制御の生物発光分析. Journal of Oral Biosciences Supplement (Web). 2023. 2023
  • 玉井雅人, 宇野智, 山田悟生, 中村翔太郎, 曽我皓平, 中道裕子, 小出雅則, 高野智弘, 宇多川信之, 清野宏, et al. Roles of IL-4 in developing bone loss associated with food allergic enteropathy. 日本農芸化学会大会講演要旨集(Web). 2022. 2022
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Books (6)：
  • Vitamin D; 5th Edition, Chapter 20 - Osteoclastogenesis and Vitamin D
    Academic Press 2023
  • Encyclopedia of Bone Biology; Vitamin D in The Regulation of Osteoclasts Pages 290-302
    Academic Press 2020
  • Chapter 18 - Osteoclastogenesis and Vitamin D
    Academic Press 2018
  • Keyword M-CSF/IL-34 骨ペディア 骨疾患・骨代謝キーワード事典
    日本骨代謝学会編/羊土社 2015
  • Encyclopedia of Bone Biology;Osteoclast Cell Lineage: Characteristics and Behavior of Osteoclast Precursors In Vivo Pages 181-192
    Academic Press 2014
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Lectures and oral presentations  (15)：
  • The Vitamin D Receptor (VDR) in Osteoblastic Cells Dictates Disease Outcomes of Calcium and Phosphate Metabolic Disorders
    (ASBMR 2024 Annual meeting (Toronto, Canada) Plenary Poster 2024)
  • The Vitamin D Receptor (VDR) in Osteoblastic Cells Dictates Disease Outcomes of Calcium and Phosphate Metabolic Disorders
    (ASBMR 2024 Energy Metabolism Pre-meeting Symposium (Toronto, Canada) , PM-023 2024)
  • The vitamin D receptor (VDR) in osteoblastic cells dictates disease outcomes of calcium (Ca) and phosphate (Pi) metabolic disorders
    (2024)
  • VDR IN OSTEOBLASTIC CELLS DICTATES DISEASE OUTCOMES OF CALCIUM AND PHOSPHATE METABOLIC DISORDERS
    (25th Vitamin D Workshop (Cork, Ireland), Trainee Travel Awards for Highly Ranked Abstracts 2024)
  • 活性型ビタミンDによるカルシウム代謝制御における骨芽細胞のビタミンD受容体(VDR)とWntシグナルの役割
    (九州歯科大学 大学院特別講義 2023)
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Education (5)：
  • - 2002 The University of Tokyo
  • - 2002 The University of Tokyo Graduate School of Agricultural and Life Sciences Department of Applied Biological Chemistry
  • - 1998 The University of Tokyo
  • - 1996 Tokyo University of Science Faculty of Science, Division 1 Chemistry
  • - 1996 Tokyo University of Science Faculty of Science Chemistry
Professional career (1)：
  • PhD (The University of Tokyo)
Work history (7)：
  • 2022/04 - Matsumoto Dental University Institute for Oral Science Associate Professor
  • 2017/09 - 2019/09 ノースカロライナ大学チャペルヒル校ラインバーガー癌センター 客員研究員
  • 2011 - - 松本歯科大学 総合歯科医学研究所 講師
  • 2011 - - Assistant Professor, Institute for Oral Science
  • 2007 - - 松本歯科大学 総合歯科医学研究所 助教
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Committee career (8)：
  • 2014/09 - 現在 JSBMR JBMM Editorial board member
  • 2014/09 - 現在 日本骨代謝学会誌 Journal of Bone and Mineral Metabolism Editorial board
  • - 2017/07 JSBMR 35th Annual Meeting Program Committee Member
  • - 2017/07 日本骨代謝学会 第35回 日本骨代謝学会プログラム選定委員
  • - 2016/07 JSBMR 34th Annual Meeting Program Committee Member
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Awards (6)：
  • 2022/09 - 24th Vitamin D Workshop Plenary Poster Award
  • 2017 - 20th Vitamin D Workshop Plenary Poster Award
  • 2016 - 第2回 Neo Vitamin D workshop 優秀演題賞
  • 2012/06 - 4th International Conference on Osteoimmunology Travel Award
  • 2004 - アメリカ骨代謝学会 Young Investigator Award
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Association Membership(s) (7)：
松本歯学会 ,  JAOB ,  Japanese Society of Osteoimmunology ,  米国骨代謝学会 ,  日本骨代謝学会 ,  ASBMR ,  JSBMR
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