Rchr
J-GLOBAL ID:200901092882061094
Update date: Oct. 10, 2023
Kai Hisashi
カイ ヒサシ | Kai Hisashi
Affiliation and department:
Kurume University School of Medicine, School of Medicine
About Kurume University School of Medicine, School of Medicine
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Detailed information
Job title:
Associate Professor
Research field (3):
Cardiology
, Cell biology
, Molecular biology
Research keywords (4):
循環器内科学 分子生物学 細胞生物学
, Cell Biology
, Molecular Biology
, Cardiology
Research theme for competitive and other funds (16):
循環器内科学の臨床疫学
心拡張能不全の防止・治療法の開発・実用化
血管形成術後再狭窄防止法の開発・実用化
循環器治療後薬副作用の背景遺伝子解析
高血圧症と高血圧合併症の臨床的研究
心血管リモデリングに関する研究
急性冠症候群の臨床的研究
心血管病に対する遺伝子治療
心血管系でのアポトーシスに関する研究
Clinical epidemiology in cardiovascular diseases
Prevention for diastolic dysfunction
Prevention for post-angioplasty restenosis
Genome analysis for target genes responsible for adverse effects of cardiovascular drugs
Clinical study on acute cownavy syndrome
Study on apotosis in cardiovascular system
Study on cardiovascular remodeling
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MISC (106):
Narimasa Takayama, Hisashi Kai, Hiroshi Kudo, Suguru Yasuoka, Takahiro Mori, Takahiro Anegawa, Mitsuhisa Koga, Hidemi Kajimoto, Yoshitaka Hirooka, Tsutomu Imaizumi. Simvastatin prevents large blood pressure variability induced aggravation of cardiac hypertrophy in hypertensive rats by inhibiting RhoA/Ras-ERK pathways. HYPERTENSION RESEARCH. 2011. 34. 3. 341-347
Yusuke Sugi, Hideo Yasukawa, Hisashi Kai, Daisuke Fukui, Nobuyoshi Futamata, Kazuhisa Mawatari, Toyoharu Oba, Nobutaka Nagata, Sachiko Kyougoku, Mitsuhisa Koga, et al. Reduction and activation of circulating dendritic cells in patients with decompensated heart failure. INTERNATIONAL JOURNAL OF CARDIOLOGY. 2011. 147. 2. 258-264
Kiyoko Takemiya, Hisashi Kai, Hideo Yasukawa, Nobuhiro Tahara, Seiya Kato, Tsutomu Imaizumi. Mesenchymal stem cell-based prostacyclin synthase gene therapy for pulmonary hypertension rats. BASIC RESEARCH IN CARDIOLOGY. 2010. 105. 3. 409-417
Hiroshi Kudo, Hisashi Kai, Hidemi Kajimoto, Mitsuhisa Koga, Narimasa Takayama, Takahiro Mori, Ayami Ikeda, Suguru Yasuoka, Takahiro Anegawa, Hiroharu Mifune, et al. Exaggerated Blood Pressure Variability Superimposed on Hypertension Aggravates Cardiac Remodeling in Rats via Angiotensin II System-Mediated Chronic Inflammation. HYPERTENSION. 2009. 54. 4. 832-U288
Kai H, Kudo H, Takayama N, Yasuoka S, Kajimoto H, Imaizumi T. Large Blood Pressure Variability and Hypertensive Cardiac Remodeling - Role of Cardiac Inflammation -. Circ J. 2009. 73. 12. 2198-2203
more...
Patents (3):
可溶型インターフェロンγ受容体遺伝子導入法および動脈硬化予防または治療用組成物
可溶型インターフェロンγ受容体遺伝子導入法
Rhoキナーゼ阻害活性を有する化合物を含有になる血管狭窄予防・治療薬
Books (1):
Endothelin and vascular constriction(共著)
Regulation of Coronary Blood Flow 1991
Works (9):
Role of JAK-STAT pathway in Vascular Remodeling
2000 - 2001
Mechanism of and treatment for diastolic dysfunction in hypertensive heart
1997 - 2001
Prevention of post-angioplasty restenosis by a Rho-kinase inhibitor
2001 -
肺高血圧症に対する遺伝子治療
血管傷害後リモデリングに対する遺伝子治療
more...
Education (2):
- 1984 Kyushu University Faculty of Medicine
Kyushu University School of Medicine
Professional career (1):
(BLANK) (Kyushu University)
Work history (5):
1998 - 2000 Kurume University, Assistant Professor
1995 - 1998 Kurume University, Research Assistant
1992 - 1995 Emory University, Visiting researcher
1991 - 1992 Kyushu University, Research Associate
1986 - 1989 Kyushu University, Research Fellow
Committee career (5):
日本心不全学会 評議員
日本老年医学会 評議員
American Heart Association International Fellow (Council for High Blood Pressure Research)
日本高血圧学会 幹事、評議員
日本循環器学会 評議員
Awards (5):
2009 - ふくおか臨床医学研究賞
2007 - ノバルティス老化及び老年医学研究基金研究助成 優秀賞
2003 - 福岡医学賞
1998 - 日本心臓財団奨励賞
1998 - 日本心臓財団・ファイザー心血管病研究優秀賞
Association Membership(s) (9):
日本動脈硬化学会
, 日本心臓病学会
, 日本心不全学会
, 日本老年医学会
, American Heart Association
, 日本心血管インターベンション治療学会
, 日本高血圧学会
, 日本循環器学会
, 日本内科学会
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