Mekada Eisuke

メカダエイスケ | Mekada Eisuke

Affiliation and department：
Job title： Professor
Other affiliations (1)：

大阪大学微生物病研究所招へい教授

Research field (4)： Bacteriology , Cell biology , Molecular biology , Functional biochemistry

Research theme for competitive and other funds (53)：

2014 - 2017 Investigation of molecular roles of tetraspanin in dual oxidase activaiton
2014 - 2017 Development of a novel anti-cancer therapeutics targeting HB-EGF
2011 - 2015 Integration and regulatory mechanism for growth factor and cell adhesion signals
2011 - 2015 The role of HB-EGF in cancer cell proliferation and malignancy
2008 - 2010 Identification of host cell factors involved in diphtheria toxin sensitivity by using shRNA library.

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Papers (134)：

Lei Zhou, Wenqing Zhou, Ann M Joseph, Coco Chu, Gregory G Putzel, Beibei Fang, Fei Teng, Mengze Lyu, Hiroshi Yano, Katrin I Andreasson, et al. Group 3 innate lymphoid cells produce the growth factor HB-EGF to protect the intestine from TNF-mediated inflammation. Nature immunology. 2022. 23. 2. 251-261
Patcharaporn Boonyos, Michittra Boonchan, Benjarat Phattanawiboon, Nutthawan Nonthabenjawan, Ratana Tacharoenmuang, Ratigorn Gunpapong, Phakapun Singchai, Sompong Upchai, Pimpha Rungnobhakhun, Jutarat Mekmullica, et al. Spread of genetically similar noroviruses in Bangkok, Thailand, through symptomatic and asymptomatic individuals. Heliyon. 2021. 7. 10. e08250-e08250
Nutthawan Nonthabenjawan, Patcharaporn Boonyos, Benjarat Phattanawiboon, Worakarn Towayunanta, Kobkool Chuntrakool, Karn Ngaopravet, Kriangsak Ruchusatsawat, Ballang Uppapong, Somchai Sangkitporn, Eisuke Mekada, et al. Identification of GII.14[P7] norovirus and its genomic mutations from a case of long-term infection in a post-symptomatic individual. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases. 2020. 86. 104612-104612
Benjarat Phattanawiboon, Nutthawan Nonthabenjawan, Patcharaporn Boonyos, Chanya Jetsukontorn, Worakarn Towayunanta, Kobkool Chuntrakool, Karn Ngaopravet, Kriangsak Ruchusatsawat, Ballang Uppapong, Somchai Sangkitporn, et al. Norovirus transmission mediated by asymptomatic family members in households. PloS one. 2020. 15. 7. e0236502
Tumkosit U, Maeda Y, Kishishita N, Siripanyaphinyo U, Omori H, Chetanachan P, Sittisaman P, Jityam C, Priengprom T, Mizushima H, et al. The use of green fluorescent protein-tagged virus-like particles as a tracer in the early phase of chikungunya infection. Virus research. 2019. 272. 197732

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MISC (133)：

岡田憲明, 岡本彩香, 清水広介, 浅井知浩, 南野哲男, 目加田英輔, 奥直人. RNA干渉効率の向上を目指した抗体修飾脂質ナノ粒子の開発. 日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会講演要旨集. 2014. 24th-2014
西川薫, 重松宏和, 浅井知浩, 南野哲男, 朝野仁裕, 高島成二, 目加田英輔, 奥直人. HB-EGF標的化リポソームの開発. 日本薬学会年会要旨集. 2010. 130th. 4. 198-198
Mizushima, H, Wang, X, Miyamoto, S, Mekada, E. Integrin signal masks growth-promotion activity of HB-EGF in monolayer cell cultures. J. Cell Sci. 2009. 122. 23. 4277-4286
堀居拓郎, 木村美香, 森田純代, 長尾恭光, 岩本亮, 目加田英輔, 畑田出穂. 体外受精に失敗したマウス未受精卵からの単為発生胚由来ES細胞の樹立とその利用. J Reprod Dev. 2009. 55. Supplement. J156
重松宏和, 浅井知浩, 南野哲男, 朝野仁裕, 高島成二, 目加田英輔, 奥直人. HB-EGF標的化リポソームによる新規ターゲティングDDSの開発. Drug Delivery System. 2009. 24. 3. 316

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Patents (29)：

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Books (14)：

Mathematical Modeling for Break Down of Dynamical Equilibrium in Bone Metabolism
Springer 2017 ISBN:9789811009624
"Toxin receptors" in The comprehensive Sourcebook of Bacterial Protein Toxins
Academic Press 2006
Diphtheria toxin and the diphtheria-toxin receptor in "Handbook of Experimental Pharmacology" ed. By Aktories K. and Just I.
Springer-Verlag, Berlin 2000
Diphtheria toxin and the diphtheria-toxin receptor in "Handbook of Experimental Pharmacology" ed. By Aktories K. and Just I.
Springer-Verlag, Berlin 2000
Diphtheria toxin and the diphtheria-toxin receptor in Handbook of Experimental Pharmacology ed. By Aktories K. and Just I.
2000

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Education (2)：

- 1974 Yamagata University Faculty of Science
- 1974 Yamagata University Faculty of Science

Professional career (1)：

(BLANK) (Osaka University)

Work history (7)：

2024/04 - 現在滋慶医療科学大学大学院客員教授
2019/02/16 - 現在 Osaka University Institute for Transdisciplinary Graduate Degree Programs Specially Appointed Professor
2000/01/01 - 2017/03/31 Osaka University Research Institute for Microbial Diseases Professor
2011/10 - 2015/10 大阪大学・微生物病研究所・所長
1988/09 - 1999/12 久留米大学教授

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Committee career (1)：

2012/04 - 2014/03 Japan Society for Cell Biology President

Association Membership(s) (4)：

Japan Society for Cell Biology , Japanese Cancer Association , 日本細菌学会 , 日本生化学会

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