Rchr
J-GLOBAL ID：200901093816490371   Update date: Oct. 08, 2024

Toba Hiroe

トバ ヒロエ | Toba Hiroe
Affiliation and department：
Kyoto Pharmaceutical University Department of Clinical Pharmacology

About Kyoto Pharmaceutical University Department of Clinical Pharmacology


Job title： Assistant professor
Research field  (3)： Pathobiochemistry ,  Physiology ,  Pharmacology
Research keywords  (14)： myocardial infarction ,  cardiac aging ,  renal diseases ,  pharmacotherapeutics ,  extracellular matrix ,  aging ,  physiology ,  cardiovascular pharmacology ,  common diseases ,  atherosclerosis ,  vascular injury ,  Common disease ,  Endothelial function ,  CKD
Research theme for competitive and other funds  (9)：
  • 2022 - 2027 SPARC関連細胞外マトリックスとマトリックス分解酵素からの動脈硬化治療ターゲットの探索
  • 2021 - 2024 anti-atherosclerotic effects of erythropoietin
  • 2021 - 2022 動脈硬化治療薬開発を目指した細胞外マトリックス研究
  • 2018 - 2021 慢性腎臓病増悪因子としての細 胞外マトリックスの役割
  • 2016 - 2017 慢性腎臓病治療ターゲット探索のための細胞外マトリックスの役割の検討
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Papers (48)：
  • Hiroe Toba, Shinji Takai. Exploring the roles of SPARC as a proinflammatory factor and its potential as a novel therapeutic target against cardiovascular disease. American journal of physiology. Heart and circulatory physiology. 2024
  • Miyuki Kobara, Tatsuya Shiraishi, Kazuki Noda, Hiroe Toba, Tetsuo Nakata. Eicosapentaenoic Acid Preserves Mitochondrial Quality and Attenuates Cardiac Remodeling After Myocardial Infarction in Rats. Journal of cardiovascular translational research. 2023
  • 鳥羽 裕恵. 薬理系薬学 動脈硬化病変は新規に構築された神経回路によって外膜側から支配されている. ファルマシア. 2023. 59. 2. 153-153
  • Miyuki Kobara, Toshihiro Amano, Hiroe Toba, Tetsuo Nakata. Nicorandil Suppresses Ischemia-Induced Norepinephrine Release and Ventricular Arrhythmias in Hypertrophic Hearts. Cardiovascular drugs and therapy. 2023. 37. 1. 53-62
  • Miyuki Kobara, Hiroe Toba, Tetsuo Nakata. Roles of autophagy in angiotensin II-induced cardiomyocyte apoptosis. Clinical and experimental pharmacology & physiology. 2022. 49. 12. 1342-1351
ｍore...
MISC (124)：
  • Miyuki Kobara, Hiroe Toba, Tetsuo Nakata. Caloric restriction, reactive oxygen species, and longevity. Aging. 2020. 11-18
  • Miyuki Kobara, Nessa Naseratun, Yuusuke Watanabe, Hiroe Toba, Tetsuo Nakata. Comparison of the effects of bisoprorol and atenorol on post-infarct cardiac remodeling. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2020. 93. 3-O
  • H Toba, A Yamaoka, S Sakurai, Y Tanaka, A Miyamoto, N Nessa, Y Watanabe, M Kobara, T Nakata. P713Short term treatment of a low dose erythropoietin improves vascular function in a rat model of insulin resistance. European Heart Journal. 2019. 40. Supplement_1
  • M Kobara, N Naseratun, Y Watanabe, H Toba, T Nakata. P6275Role of autophagy in imatinib-induced cardiotoxicity. European Heart Journal. 2019. 40. Supplement_1
  • M Kobara, N Naseratun, Y Watanabe, H Toba, T Nakata. P1603Nicorandil suppresses ischemia-induced cardiac interstitial norepinephrine enhancement and ventricular arrhythmia in hypertrophic hearts. European Heart Journal. 2019. 40. Supplement_1
ｍore...
Books (2)：
  • Inflammation in Heart Failure
    Academic Press 2015
  • Somatic stem cells and cardiac regeneration. Pathophysiological and Biochemical Analyses of “Life-Style Related or Intractable Diseases”
    Target Validation for Drug Therapy 2006
Lectures and oral presentations  (198)：
  • SPARC expression increases in accordance with acute renal dysfunction after ischemia/reperfusion
    (2024)
  • 高血圧性臓器障害増悪因子としての細胞外マトリックスとプロテアーゼの役割
    (第28回日本病態プロテアーゼ学会学術集会 2023)
  • 理系のすすめ
    (高校生対象模擬講義 2023)
  • 高血圧性血管障害における細胞外マトリックスSPARCの役割の検討
    (日本薬学会 第143回年会)
  • インスリン抵抗性モデルラットの耐糖能異常と臓器障害に対するエリスロポエチンの効果の検討
    (日本薬学会 第143回年会)
ｍore...
Professional career (1)：
  • PhD (Kyoto Pharmaceutical University)
Work history (5)：
  • 2007/04 - 現在 Kyoto Pharmaceutical University Department of Clinical Pharmacology Assistant Professor
  • 2013/08 - 2015/07 University of Mississippi Medical Center Department of Physiology & Biophysics Visiting Assisstant Professor
  • 2007/04 - 2013/03 明治国際医療大学 鍼灸学部・保健医療学部 非常勤講師
  • 2002/04 - 2007/03 Kyoto Pharmaceutical University Department of Clinical Pharmacology Research Associate
  • 2000/04 - 2002/03 Kyoto Prefectural University of Medicine Department of Pathology and Applied Neurobiology Visiting Researcher
Committee career (2)：
  • 2023/09 - 現在 日本高血圧学会 学術評議員
  • 2016 - 現在 日本薬理学会 学術評議員
Awards (2)：
  • 2018/09 - The 42nd Annual Scientific Meeting of the Japanese Society of Hypertension JSH Women Investigator’s Award
  • 2006/10 - The 21st Scientific Meeting of the International Society of Hypertension JSH Award (Young Investigators Awards and Travel Grants)
Association Membership(s) (9)：
The Pharmaceutical Society of Japan ,  THE JAPANESE PHARMACOLOGICAL SOCIETY ,  Japanese Association of Cardiovascular Pharmacology ,  JAPANESE CIRCULATION SOCIETY ,  THE JAPANESE SOCIETY OF HYPERTENSION ,  JAPANESE SOCIETY FOR CIRCULATION RESEARCH ,  American Heart Association ,  The American Physiological Society ,  THE JAPANESE SOCIETY OF CLINICAL PHARMACOLOGY AND THERAPEUTICS
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