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J-GLOBAL ID:200901094037594647   Update date: Aug. 16, 2024

Kengaku Mineko

Kengaku Mineko
Affiliation and department:
Job title: Professor
Other affiliations (1):
  • Graduate School of Biostudies  Professor
Homepage URL  (1): http://www.kengaku.icems.kyoto-u.ac.jp/
Research field  (2): Neuroscience - general ,  Developmental biology
Research keywords  (26): 接線移動 ,  クラスリン ,  シナプス ,  細胞骨格 ,  選択輸送 ,  内顆粒層(IGL) ,  細胞分化 ,  小脳 ,  外顆粒層(EGL) ,  極性輸送 ,  細胞間相互作用 ,  細胞移動 ,  核移動 ,  神経細胞移動 ,  Wntシグナル ,  顆粒細胞 ,  プルキンエ細胞 ,  Pax6 ,  DNER ,  樹状突起 ,  小脳顆粒細胞 ,  中枢神経系ニューロン ,  細胞極性 ,  包括脳ネットワーク ,  統合脳・分子脳科学 ,  統合脳・神経回路機能
Research theme for competitive and other funds  (24):
  • 2022 - 2027 Mechanical self-transformation of living systems
  • 2022 - 2027 Cooperation of mechanical forces during brain architecture formation
  • 2020 - 2024 Regulatory mechanism of neuronal migration in 3D brain tissue
  • 2021 - 2023 新生ニューロンのDNA損傷に由来する脳ゲノム不均一性の検証
  • 2021 - 2023 Molecular mechanism of chromatin protection by planned DNA breaks in the developing brain
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Papers (57):
  • Chuying Zhou, You Kure Wu, Fumiyoshi Ishidate, Takahiro K Fujiwara, Mineko Kengaku. Nesprin-2 coordinates opposing microtubule motors during nuclear migration in neurons. The Journal of cell biology. 2024. 223. 11
  • CHUYING ZHOU, MINEKO KENGAKU. Possible mechanisms of bidirectional nuclear transport during neuronal migration. BIOCELL. 2022. 46. 11. 2357-2361
  • Toshio Takahashi, Kazuto Fujishima, Mineko Kengaku. Modeling Intestinal Stem Cell Function with Organoids. International Journal of Molecular Sciences. 2021. 22. 20. 10912-10912
  • Mitsuhiro Nakato, Naoko Shiranaga, Maiko Tomioka, Hitomi Watanabe, Junko Kurisu, Mineko Kengaku, Naoko Komura, Hiromune Ando, Yasuhisa Kimura, Noriyuki Kioka, et al. ABCA13 dysfunction associated with psychiatric disorders causes impaired cholesterol trafficking. Journal of Biological Chemistry. 2021. 296. 100166-100166
  • Kazuto Fujishima, Junko Kurisu, Midori Yamada, Mineko Kengaku. βIII spectrin controls the planarity of Purkinje cell dendrites by modulating perpendicular axon-dendrite interactions. Development. 2020. 147. 24. dev194530-dev194530
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MISC (12):
Books (7):
  • Principles of Neural Science, 6th Edition
    2022 ISBN:9784815730550
  • 生体の科学 - 特集 メカノバイオロジー
    公益財団法人金原一郎記念医学医療振興財団/医学書院 2019
  • 京大発!フロンティア生命科学
    講談社 2018
  • 脳神経化学 - 脳はいま化学の言葉でどこまで語れるか-
    化学同人 2018
  • 数理解析による樹状突起分岐ダイナミクスとパターン形成原理の解明、ブレインサイエンス・レビュー2012
    クバプロ/(財)ブレインサイエンス振興財団 2012
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Lectures and oral presentations  (77):
  • Force Transmission to the Nucleus during Neuronal Migration in the Developing Brain
    (International Symposium on Neural Development and Diseases 2023)
  • Calcium signals tune AMPK activity and mitochondrial homeostasis in growing dendrites of mouse hippocampal neurons
    (Universität Hamburg-Kyoto University Join Symposium 2023)
  • 3D neuronal migration driven by multiple engines
    (2022)
  • Dynamic interplay of cytoskeletal motors during neuronal migration in the developing brain
    (2022)
  • Cytoskeletal forces driving neuronal migration in 3D brain tissues.
    (International Symposium on Development and Plasticity of Neural Systems 2022)
more...
Professional career (1):
  • Ph.D in Medicine
Work history (10):
  • 2017/04 - 現在 Kyoto University
  • 2012/11 - 2017/03 Kyoto University
  • 2008/10 - 2012/10 Kyoto University
  • 2004/01 - 2008/09 RIKEN
  • 2002/01 - 2003/12 京都大学 大学院 理学研究科・講師
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