KOBAYASHI Kenji

コバヤシケンジ | KOBAYASHI Kenji

Affiliation and department：

Research field (3)： Developmental biology , Cell biology , Neuroscience - general

Research keywords (20)：脊索動物 , 尾索動物 , ホヤ , Tadpole larva , 個体発生 , 胚発生 , 細胞分化 , Cell proliferation , Cell cycle , Neuron , 遺伝子 , 遺伝子発現 , Microinjection , Genome editing , Cell sorter , RNA-seq , ATAC-seq , 1細胞 , Single cell , Transcriptome

Research theme for competitive and other funds (7)：

2024 - 2027 ホヤ幼生の神経系細胞の発生過程における細胞増殖制御機構の解明ー増殖と分化相関
2023 - 2024 酩酊症株の遺伝的特徴を模した高エタノール産生カンジダ株の創出
2022 - 2023 Interplay between cell cycle control and differentiation of neural cells in ascidian larvae
2008 - 2008 カタユウレイボヤの胚発生過程における細胞周期制御因子の転写レベルでの発現パターンの解析
2007 - 2008 Communication between cell proliferation and differentiation of muscle, notochord, and nerve cells in ascidian embryos

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Papers (21)：

Kenji KOBAYASHI*#, Miki TOKUOKA*#, Hiroaki SATO, Manami ARIYOSHI, Shiori KAWAHARA, Shigeki FUJIWARA, Takeo KISHIMOTO, Yutaka SATOU, (*#: equally contribution & corresponding authors). Regulators specifying cell fate activate cell cycle regulator genes to determine cell numbers in ascidian larval tissues. Development. 2022. 149. 2. dev201218
Miki TOKUOKA, Kenji KOBAYASHI, Patrick LEMAIRE, Yutaka SATOU. Protein kinases and protein phosphatases encoded in the Ciona robusta genome. Genesis. 2022. 60. e23471
Miki TOKUOKA, Kazuki MAEDA, Kenji KOBAYASHI, Atsushi MOCHIZUKI, Yutaka SATOU. The gene regulatory system for specifying germ layers in early embryos of the simple chordate. Science Advances. 2021. 7. 24. eabf8210
Kenji KOBAYASHI, Kazuki MAEDA, Miki TOKUOKA, Atsushi MOCHIZUKI,Yutaka SATOU. Using linkage logic theory to control dynamics of a gene regulatory network of a chordate embryo. Scientific Reports. 2021. 11. 1. 4001
Kaoru S. IMAI, Kenji KOBAYASHI, Willi KARI, Ute ROTHBÄCHER, Naoki OOKUBO, Izumi ODA-ISHII, Yutaka SATOU. Gata is ubiquitously required for the earliest zygotic gene transcription in the ascidian embryo. Developmental Biology. 2020. 458. 2. 215-227

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MISC (2)：

Kenji KOBAYASHI, Yutaka SATOU. Microinjection of exogenous nucleic acids into eggs: Ciona species. Advances in Experimental Medicine and Biology. 2018. 1029. 5-13
Shuichi WADA, Lixy YAMADA, Kenji KOBAYASHI, Eiichi SHOGUCHI, Noriyuki SATOH. [Morpholino oligonucleotide-based screen of novel genes with developmental function]. Seikagaku. 2003. 75. 7. 617-620

Education (4)：

1999 - 2002 Tokyo Institute of Technology Graduate School of Bioscience and Biotechnology
1997 - 1999 Tokyo Institute of Technology Graduate School of Bioscience and Biotechnology
1993 - 1997 Tokyo Institute of Technology School of Bioscience and Biotechnology
1990 - 1993 栃木県立栃木高等学校普通科(全日制)

Professional career (1)：

PhD (Tokyo Institute of Technology)

Work history (11)：

2022/04 - 現在 Osaka University Graduate School of Frontier Biosciences
2020/11 - 2021/06 リージョナルフィッシュ株式会社研究開発部無脊椎育種グループ主任研究員 / 研究スペシャリスト
2019/07 - 2020/10 Hiroshima University Graduate School of Integrated Sciences for Life, Marine Biological Laboratory Assistant Professor (Specially Appointed)
2014/01 - 2019/06 Kyoto University Graduate School of Science, Division of Biological Sciences Program-Specific Researcher (JST CREST)
2012/04 - 2013/03 Tokyo Institute of Technology Graduate School of Bioscience and Biotechnology, Department of Biological Information

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