Rchr
J-GLOBAL ID：200901095635197918   Update date: Oct. 30, 2024

Nakanishi Ikuo

ナカニシ イクオ | Nakanishi Ikuo
Affiliation and department：
National Institutes for Quantum Science and Technology Quantum RedOx Chemistry Team, Quantum Life Spin Group, Institute for Quantum Life Science

About National Institutes for Quantum Science and Technology Quantum RedOx Chemistry Team, Quantum Life Spin Group, Institute for Quantum Life Science


Job title： Team Leader
Homepage URL  (1)： http://ikuo.com/
Research field  (5)： Pharmaceuticals - analytical and physicochemistry ,  Biochemistry ,  Bioorganic chemistry ,  Structural/physical organic chemistry ,  Basic physical chemistry
Research keywords  (9)： Redox Chemistry ,  Electron Spin Resonance ,  Kinetics ,  Reaction Mechanism ,  Radical ,  電子移動 ,  Antioxidant ,  Reactive Oxygen Species ,  Physical Chemistry for Life Science
Research theme for competitive and other funds  (14)：
  • 2024 - 2025 抗酸化物質によるラジカル消去反応の量子機構に対する反応環境の影響
  • 2018 - 2021 Kinetic Activity Evaluation of Antioxidants in Aqueous Solutions Using a Water-Solubilized Organic Radical
  • 2014 - 2017 Development of pH-Responsive Antioxidants as Radioprotectors for Normal Tissues
  • 2011 - 2014 Development of Novel Antioxidants Based on Thermodynamic Parameters Calculated by Density Functional Theory
  • 2009 - 2011 Mechanistic Study on the Pro-oxidant Effects by Antioxidants
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Papers (127)：
  • Hiroko P. Indo, Moragot Chatatikun, Ikuo Nakanishi, Ken-ichiro Matsumoto, Motoki Imai, Fumitaka Kawakami, Makoto Kubo, Hiroshi Abe, Hiroshi Ichikawa, Yoshikazu Yonei, et al. The Roles of Mitochondria in Human Being’s Life and Aging. Biomolecules. 2024. 14. 10. 1317-1317
  • Wakana Shimizu, Yoshimi Shoji, Kei Ohkubo, Hiromu Ito, Ikuo Nakanishi, Kiyoshi Fukuhara. Antioxidant Activity of Planar Catechin Conjugated with Trolox. Antioxidants. 2024. 13. 10. 1165-1165
  • Hiromu Ito, Yoshimi Shoji, Ken-ichiro Matsumoto, Kiyoshi Fukuhara, Ikuo Nakanishi. A Mechanism for Apoptotic Effects of a Planar Catechin Analog on Cancer Cells. Molecules. 2024. 29. 18. 4467-4467
  • Ryota Mori, Masami Abe, Yuma Saimoto, Saki Shinto, Sara Jodai, Manami Tomomatsu, Kaho Tazoe, Minato Ishida, Masataka Enoki, Nao Kato, et al. Construction of a screening system for lipid-derived radical inhibitors and validation of hit compounds to target retinal and cerebrovascular diseases. Redox Biology. 2024. 73. 103186-103186
  • Yoshimi Shoji, Yuri Terashima, Kei Ohkubo, Hiromu Ito, Kouichi Maruyama, Shunichi Fukuzumi, Ikuo Nakanishi. Scandium Ion-Promoted Electron-Transfer Disproportionation of 2-Phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl 3-Oxide (PTIO•) in Acetonitrile and Its Regeneration Induced by Water. International Journal of Molecular Sciences. 2024. 25. 8. 4417-4417
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MISC (101)：
  • Wakana Shimizu, Yoshimi Shoji, Kei Ohkubo, Hiromu Ito, Ikuo Nakanishi, Kiyoshi Fukuhara. Antioxidant Activity of Planar Catechin Conjugated with Trolox. Reprints. 2024. 2024081751-2024081751
  • Ken-ichiro Matsumoto, Ikuo Nakanishi, Hiromu Ito. Radiation Damage and Oxidative Stress. Journal of Clinical and Experimental Medicine. 2024. 289. 4. 271-274
  • Ikuo Nakanishi, Yoshimi Shoji, Kei Ohkubo, Toshihiko Ozawa, Ken-ichiro Matsumoto, Shunichi Fukuzumi. pH Effect on the Scavenging Rates of Ascorbic Acid against Selected Radicals in Phosphate Buffer Solutions. Free Radical Biology and Medicine. 2022. 180. Supplement 1. s64-s64
  • 稲庭拓, 鈴木雅雄, 岩田義之, 佐藤眞二, 水島康太, 下川卓志, 阿部康志, 坂田洞察, 長谷川純崇, 中島菜花子, et al. Studies for Magneto-Particle Therapy. 量子科学技術研究開発機構研究報告書(Web). 2020. 17
  • Hideyuki Majima, Hiromu Ito, Tomoko Fukushige, Hiroko Indo, Yoshihiro Kawabata, Ken-Ichiro Matsumoto, Ikuo Nakanishi, Akihide Tanimoto, Takuro Kanekura, Clare Hawkins, et al. Effects of Extremely Small Doses, 100 mGy a Day, Five Times a Week, Total of Twelve Weeks of Low-Dose Fractionated X-irradiation on Mice Hair Root. FREE RADICAL BIOLOGY AND MEDICINE. 2019. 145. S31-S32
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Patents (4)：
  • SCREENING METHOD, SCREENING KIT AND ANALYSIS PROGRAM
  • スクリーニング方法、スクリーニングキット、及び解析プログラム
  • 酵母を有効成分とする放射線防護剤
  • N-フッ素化アルキルピペリジンメタノール誘導体及びこれを含有する中枢局所アセチルおよびブチリルコリンエステラーゼ活性測定用試薬
Books (5)：
  • 酸化ストレスの医学 改訂第3版
    診断と治療社 2024 ISBN:9784787826206
  • Generation of Oxygen Radicals and DNA-Cleaving Ability in Quinone/NADH System
    Magnetic Resonance in Medicine 2002
  • フラーレンの光増感反応による活性酸素生成とDNA損傷のメカニズム
    <i>放射線科学</i> 2002
  • Generation of Oxygen Radicals and DNA-Cleaving Ability in Quinone/NADH System
    Magnetic Resonance in Medicine 2002
  • Mechanism of Generation of Reactive Oxygen Species and DNA Damage by Photosensitized Reactions of Fullerenes
    Radiological Sciences 2002
Lectures and oral presentations  (9)：
  • 抗酸化物質の量子レドックス化学
    (フリーラジカルスクール2024 2024)
  • レドックス不活性な金属イオンによるフリーラジカル消去反応
    (第77回日本酸化ストレス学会 第23回日本NO学会 合同学術集会 2024)
  • Reactivity of a Nitronyl Nitroxide Radical in the Presence of Redox-Inactive Metal Ions
    (The 144th Annual Meeting of the Pharmaceutical Society of Japan 2024)
  • 抗酸化物質によるラジカル消去反応の量子生命科学
    (Free Radical School 2023 2023)
  • Electron-Transfer Disproportionation of a Nitronyl Nitroxide Radical by Scandium Ion
    (SEST2023 2023)
ｍore...
Education (4)：
  • 1996 - 1999 Osaka University Graduate School of Engineering Department of Material and Life Science
  • 1994 - 1996 Osaka Prefecture University Graduate School of Engineering Department of Applied Chemistry
  • 1990 - 1994 Osaka Prefecture University Faculty of Engineering Department of Applied Chemistry
  • 1986 - 1989 Osaka Prefectural Kitano High School General Course
Professional career (1)：
  • Ph.D. (Osaka University)
Work history (14)：
  • 2024/04 - 現在 National Institutes for Quantum Science and Technology (QST) Quantum RedOx Chemistry Team, Quantum Life Spin Group, Institute for Quantum Life Science (iQLS) Team Leader
  • 2022/04 - 2024/03 National Institutes for Quantum Science and Technology Quantum RedOx Chemistry Team, Institute for Quantum Life Science, Quantum Life and Medical Science Directorate Team Leader
  • 2021/04 - 2022/03 National Institutes for Quantum and Radiological Science and Technology Quantum Redox Chemistry Group, Institute for Quantum Life Science, Quantum Life and Medical Science Directorate Group Leader
  • 2019/04 - 2021/03 National Institutes for Quantum and Radiological Science and Technology Department of Basic Medical Sciences for Radiation Damages, National Institute of Radiological Sciences, Quantum Medical Science Directorate Senior Principal Researcher
  • 2010/12 - 2021/03 Shibaura Institute of Technology Graduate School of Engineering and Science Visiting Professor
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Committee career (15)：
  • 2023/06 - 現在 一般社団法人 日本抗加齢医学会 評議員
  • 2020/12 - 現在 一般社団法人 日本酸化ストレス学会 総務委員
  • 2020/01 - 現在 一般社団法人電子スピンサイエンス学会 代議員
  • 2018/04 - 現在 一般社団法人日本酸化ストレス学会 代議員
  • 2017/08 - 現在 一般社団法人日本酸化ストレス学会 倫理委員
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Awards (8)：
  • 2019/06 - Society for Free Radical Research Japan (SFRR Japan) The SFRR Japan Award of Scientific Excellence
  • 2010/10 - The Society of Pure & Applied Coordination Chemistry (SPACC) The SPACC Young Investigator Award Metal Ion-Accelerated Radical-Scavenging Reactions of Phenolic Antioxidants
  • 2009/06 - AOB研究会 AOB (Anti-Oxidant Biofactor)研究会奨励賞 金属イオン存在下におけるビタミンEモデルに由来するフェノキシルラジカルのキャラクタリゼーション
  • 2008/10 - The Society of Electron Spin Science and Technology (SEST) SEST Young Investigator Award
  • 2008 - 国際フリーラジカル学会SFRR Japan Young Investigator Award 2008
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Association Membership(s) (11)：
Quantum Life Science Society ,  THE JAPAN RADIATION RESEARCH SOCIETY ,  Japanese Society of Anti-Aging Medicine ,  Society for Free Radical Research JAPAN ,  The Society of Electron Spin Science and Technology (SEST) ,  The Pharmaceutical Society of Japan ,  The Chemical Society of Japan ,  The Society of Pure & Applied Coordination Chemistry (SPACC) ,  ビタミンE研究会 ,  Society for Redox Biology and Medicine (SfRBM) ,  AMERICAN CHEMICAL SOCIETY
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