Rchr
J-GLOBAL ID:200901095778601892   Update date: Jul. 06, 2021

Mitsuru Okuwaki

オクワキ ミツル | Mitsuru Okuwaki
Affiliation and department:
Homepage URL  (1): https://www.kitasato-u.ac.jp/pharm/
Research field  (4): Molecular biology ,  Cell biology ,  Virology ,  Genetics
Research theme for competitive and other funds  (15):
  • 2017 - 2020 ヒストンシャペロンによる遺伝子発現制御機構の解明
  • 2017 - 2020 核膜孔タンパク質の質的変化による細胞運命の決定
  • 2014 - 2017 A novel mechanism of cell growth regulation by the intrinsically disordered protein, NPM1
  • 2013 - 2016 Dynamic regulation of chromatin by histone chaperone
  • 2009 - 2014 Regulatory functions of IDPs in the nuclear network of the genetic information systems
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Papers (61):
  • Hiroko Hirawake-Mogi, Nguyen Thi Thanh Nhan, Mitsuru Okuwaki. G-patch domain-containing protein 4 localizes to both the nucleoli and Cajal bodies and regulates cell growth and nucleolar structure. Biochemical and Biophysical Research Communications. 2021. 559. 99-105
  • Mitsuru Okuwaki, Ai Saotome-Nakamura, Masashi Yoshimura, Shoko Saito, Hiroko Hirawake-Mogi, Takeshi Sekiya, Kyosuke Nagata. RNA-recognition motifs and glycine and arginine-rich region cooperatively regulate the nucleolar localization of nucleolin. The Journal of Biochemistry. 2021. 169. 1. 87-100
  • Mitsuru Okuwaki, Shoko Saito, Hiroko Hirawake-Mogi, Kyosuke Nagata. The interaction between nucleophosmin/NPM1 and the large ribosomal subunit precursors contribute to maintaining the nucleolar structure. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 2021. 1868. 1. 118879-118879
  • Michelle Jane Genoveso, Miharu Hisaoka, Tetsuro Komatsu, Harald Wodrich, Kyosuke Nagata, Mitsuru Okuwaki. Formation of adenovirus DNA replication compartments and viral DNA accumulation sites by host chromatin regulatory proteins including NPM1. The FEBS Journal. 2019
  • Takeshi Sekiya, Yifan Hu, Kohsuke Kato, Mitsuru Okuwaki, Atsushi Kawaguchi, Kyosuke Nagata. Assembly and remodeling of viral DNA and RNA replicons regulated by cellular molecular chaperones. Biophysical Reviews. 2018. 10. 2. 445-452
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MISC (13):
Books (8):
  • 目的別で選べるタンパク質発現プロトコール
    2010
  • タンパク質-RNA複合体による核小体形成機構
    2005
  • ヒストンシャペロンの動的役割分担.
    2005
  • 熱帯熱マラリア原虫における抗参加タンパク質遺伝子転写制御の解析
    2004
  • 酸性分子シャペロンによるゲノム-塩基性タンパク質複合体の機能制御
    2004
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Lectures and oral presentations  (7):
  • ヒストンシャペロンによる核小体機能制御
    (____ 2005)
  • 核小体形成の制御機構
    (____ 2005)
  • Regulation of nucleolar chromatin structure by ribonucleoprotein complexes
    (____ 2005)
  • Biochemical and Physiological Functions of Histone/Acidic Melecular Chaperones
    (____ 2004)
  • Regulation of the nucleolar chromaitn structure through ribonucleoprotein complexes
    (____ 2004)
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Education (2):
  • - 1999 Tokyo Institute of Technology
  • - 1994 Tokyo Institute of Technology
Work history (6):
  • 2018/04 - 現在 Kitasato University School of Pharmacy Professor
  • 2007/12 - 2018/03 University of Tsukuba University of Tsukuba Associate Professor
  • 2004/04/01 - 2007/11/30 University of Tsukuba
  • 2003/05/16 - 2004/03/31 University of Tsukuba Institute of Basic Medical Sciences
  • 2002/04/01 - 2003/05/15 Cancer Research UK Research Fellow
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Association Membership(s) (3):
日本薬学会 ,  The Molecular Biology Society of Japan ,  THE JAPANESE BIOCHEMICAL SOCIETY
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