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J-GLOBAL ID：200901095852909934   Update date: Oct. 25, 2024

Okumura Nobuo

オクムラ ノブオ | Okumura Nobuo
Affiliation and department：
Shinshu University School of Medicine Department of Biomedical Laboratory Sciences

About Shinshu University School of Medicine Department of Biomedical Laboratory Sciences


Job title： Professor
Research keywords  (6)： Biomedical Laboratory Sciences ,  Clinical Laboratory Sciences ,  Clinical Chemistry ,  Clinical Immunology ,  Genetic testing ,  Thrombosis and Haemostasis
Research theme for competitive and other funds  (12)：
  • 2020 - 2022 血清中シトルリン化フィブリノーゲン測定による好中球細胞外トラップ検出の検討
  • 2020 - 2022 分子異常フィブリノゲンの細胞外マトリックス機能に与える影響の評価と重要部位の同定
  • 2017 - 2019 フィブリノゲン機能異常症例の解析からフィブリン重合機序の詳細を解明する研究
  • 2014 - 2016 肝硬変を引き起こすフィブリノゲン低下症の鑑別法の開発と分子生物学的発生機序解明
  • 2013 - 2015 血漿および関節液中のシトルリン化フィブリノゲンとその抗体定量法の確立.
Show all
Papers (141)：
  • Han Y, Kato M, Ashihara N, Higuchi Y, Matoba H, Wang W, Hayashi H, Itoh Y, Takahashi S, Kurita H, Nakayama J, Okumura N, Hiratsuka S. Citrullinated fibrinogen-SAAs complex causes vascular metastagenesis. Nature Communications. 2023. 14. 1. 4960
  • Kaido T, Yoda M, Kamijo T, Arai S, Taira C, Higuchi Y, Okumura N. A novel amino acid substitution, fibrinogen Bbetap.Pro234Leu, associated with hypofibrinogenemia causing impairment of fibrinogen assembly and secretion. Int. J. Mol. Sci. 2021. 21. 9422; doi:10.3390/ijms21249422
  • Osada M, Maruyama K, Kokame K, Denda R, Yamazaki K, Kunieda H, Hirao M, Madoiwa S, Okumura N, Murata M, Ikeda Y, Watanabe K, Tsukada Y, Kikuchi T. A novel homozygous variant of the thrombomodulin gene causes a hereditary bleeding disorder. Blood Advance. 2021. 5. 3830-3838
  • Arai S, Kamijo T, Kaido T, Yoda M, Shinohara S, Suzuki T, Arai N, Sugano M, Uehara T, Okumura N. Automated screening procedure for phenotype of congenital fibrinogen disorder using novel parameters, |min1|c and Ac/|min1|c obtained from clot waveform analysis of Clauss method. Clinica Chimica ACTA. 2021. 521. 170-176
  • Yoda M, Kaido T, Kamijo T, Taira C, Higuchi Y, Arai S, Okumura N. Novel variant fibrinogen gammap.C352R produced hypodysfibrinogenemia leading to a bleeding episode and failure of infertility treatment. Int J Hematology. 2021. 114. 325-333
ｍore...
Books (1)：
  • 臨床検査法提要改訂第35版
    金井正光監修,奥村伸生,戸塚 実,本田孝行,矢冨 裕 編,金原出版(東京) 2020
Education (2)：
  • - 1982 Science University of Tokyo Faculty of Science
  • - 1977 School of Allied Medical Sciences, Shinshu University
Professional career (1)：
  • Ph.D. (Shinshu University)
Awards (3)：
  • 2006 - 日本臨床検査同学院 緒方富雄賞
  • 2004 - 日本臨床検査医学会 Bergmeyer-Kawai賞
  • 1995 - 黒住医学研究振興財団 小島三郎記念技術賞
Association Membership(s) (7)：
International Society for Thrombosis and Haemostasis ,  International Fibrinogen Research Society ,  Japanese Society of Laboratory Automation ,  Japanese Society of Laboratory Hematology ,  Japanese Society of Thrombosis and Hematostasis ,  Japanese Societ of Clinical Chemistry ,  Japanese Society of LaboratoryMedicine
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