Research theme for competitive and other funds (27):
2023 - 2026 Fundamental Studies on anhydrobiosis of mammalian cells
2022 - 2024 高浸透圧傷害克服による魚類と両生類の卵子の凍結保存
2018 - 2023 Preservation of mammalian genetic resources and study for the developmental mechanism using freeze-dried cells
2020 - 2022 Trial for cryopreservation of fish oocytes
2014 - 2019 The qualitative validation in the unique wild rodents origin bio-resource such as genus Apodemus, which contains Japanese endemic and European common species
2014 - 2017 A trial to overcome the injury caused by chilling/heat stress in oocytes/embryos by controlling temperature-sensitive channel activities
2015 - 2016 Cryopreservation of fish oocytes -based on the mechanism of cell injuries during cryopreservation-
2012 - 2014 The mechanism by which oocytes/embryos are injured at low/high temperatures
2011 - 2014 Development of the cryopreservation method for fish oocytes and ovaries
2011 - 2014 The improvement of the tolerance of mammalian oocytes to cryopreservation by inducing endogenous expression of water/cryoprotectant channels or by gating the channels
2011 - 2013 Construction of original research infrastructure to investigate life phenomenon of great diversity
2008 - 2010 Cryopreservation of oocytes and embryos by inducing the expression of cryoprotectant channels.
2007 - 2009 Cryopreservation of laboratory fish oocytes
2007 - 2009 Utilization of the high pressure freezing as a gamete cryopreservation procedure for mammalian bio-resource maintenances
2005 - 2006 生理的溶液を用いた生殖細胞の高圧ガラス化凍結:究極の凍結保存法を目指して
2004 - 2006 The modulation of the tolerance of oocytes to cryopreservation by artificial expression of water channels -vertebrates and invertebrates-
2003 - 2003 魚類卵子の凍結保存 -マウスからメダカへ-
2002 - 2003 The study for cryopreservation of vertebrate oocytes and embryos by artificially expression of gene products involved in cryo-tolerance
2000 - 2002 Development of an efficient system for cryopreservation of oocytes and embryos by use of ultrarapid vitrification
2001 - 2001 卵子や胚の耐凍性を決定している遺伝子の単離
1996 - 1996 人工胎盤の開発のための基礎的研究
1996 - 1996 家禽胚の超低温保存に関する研究
1994 - 1994 一酸化窒素による排卵過程の制御機構の解析
1992 - 1992 ヒト末梢血好中球のTNF-α及びG-CSFによるpriming機構の解析
1992 - 動物の卵子および初期胚の超低温保存に関する研究
1992 - Studies on the cryopreservation of oocytes and embryos.
1990 - 1991 Ca^<++>-dependent phospholipid binding 39 K protein in neutrophil : Analysis of biological action by gene expression
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Papers (81):
Juan Qiu, Kazutsugu Matsukawa, Keisuke Edashige. Equilibrium vitrification of oocytes using low concentrations of cryoprotectants. Cryobiology. 2023. 113. 104586-104586
Yodo Sugishita, Lingbo Meng, Yuki Suzuki-Takahashi, Sandy Nishimura, Sayako Furuyama, Atsushi Uekawa, Akiko Tozawa-Ono, Junko Migitaka-Igarashi, Tomoe Koizumi, Hibiki Seino, et al. Quantification of residual cryoprotectants and cytotoxicity in thawed bovine ovarian tissues after slow freezing or vitrification. Human reproduction (Oxford, England). 2021. 37. 3. 522-533
Juan Qiu, Ayumi Hasegawa, Keiji Mochida, Atsuo Ogura, Chihiro Koshimoto, Kazutsugu Matsukawa, Keisuke Edashige. Equilibrium vitrification of mouse embryos using low concentrations of cryoprotectants. Cryobiology. 2021. 98. 127-133
Juan QIU, Kazutsugu MATSUKAWA, Chihiro KOSHIMOTO, Keisuke EDASHIGE. Equilibrium vitrification of mouse embryos at various developmental stages using low concentrations of cryoprotectants. Journal of Reproduction and Development. 2021. 67. 2. 109-114
Keisuke Edashige. The movement of water and cryo-protectants in mammalian oocytes and embryos: membrane permeability and aquaporins. Cryobiology. 2018. 85. 126-126
Keisuke Edashige, Yuki Iwahara, Shota Nariai, Yuko Nishiya, Mizuho Kitayama, Saori Niimi, Shinsuke Seki, Chihiro Koshimoto, Kazutsugu Matsukawa, Magosaburo Kasai. Coldsensitive ion channels are involved in chilling injury of pig oocytes. Cryobiology. 2016. 73. 430-431
The Society for Cryobiology
, The Society for the Study of Reproduction
, 日本繁殖生物学会
, 基礎生殖免疫学会
, 日本実験動物学会
, 日本畜産学会
, 日本生化学会
, The Society for Cryobiology
, The Society for the Study of Reproduction