Rchr
J-GLOBAL ID：200901095933696625
Update date: Feb. 12, 2021
Suzuki Yuko
スズキ ユウコ | Suzuki Yuko
Affiliation and department：
Job title：
Chief Researcher
Research field (2)：
Experimental pathology
, Cell biology
Research keywords (10)：
stem cells
, ヒト多能性幹細胞
, 再生医学
, 治療
, 筋ジストロフィー
, 骨格筋
, cell transplantation
, regeneration
, muscular dystrophy
, skeletal muscle
Research theme for competitive and other funds (12)：
- 2019 - 2022 Notchシグナルによるヒト骨格筋前駆細胞の増殖・分化制御機構の解明
- 2016 - 2019 application of induced mesenchymal stem cells from human iPS cells to cell therapy in muscular dystrophy
- 2013 - 2016 Elucidation of the mechanisms of skeletal muscle hypertrophy by intracellular calcium concentration.
- 2012 - 2015 Induction of transplantable myogenic cells from pluripotent stem cells
- 2011 - 2013 Determination of disease causing mechanisms of neuromyelitis optica by analyzing alpha1-syntrophin deficient mice
- 2008 - 2013 Cell therapy for muscular dystrophy
- 2009 - 2011 The elucidation of the molecular mechanisms of NO-mediated muscle atrophy
- 2008 - 2010 Study on molecular regulation of muscle regeneration by mesenchymal cells
- 2006 - 2007 Analysis of the roles of POMGnT1 in development and maintenance of certral nervous system and skeletal muscle
- 2004 - 2005 Analysis of roles for osteopontin in muscle regeneration
- 筋ジストロフィーの細胞治療
- 筋疾患に対する治療薬の創出を目指した研究
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Papers (69)：
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Ken’ichiro Nogami, Yusuke Maruyama, Ahmed Elhussieny, Fusako Sakai-Takemura, Jun Tanihata, Jun-ichi Kira, Yuko Miyagoe-Suzuki, Shin’ichi Takeda. iNOS is not responsible for RyR1 S-nitrosylation in mdx mice with truncated dystrophin. BMC Musculoskeletal Disorders. 2020. 21. 1. 479
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Fusako Sakai-Takemura, Ken’ichiro Nogami, Ahmed Elhussieny, Kota Kawabata, Yusuke Maruyama, Naohiro Hashimoto, Shin’ichi Takeda, Yuko Miyagoe-Suzuki. Prostaglandin EP2 receptor downstream of Notch signaling inhibits differentiation of human skeletal muscle progenitors in differentiation conditions. Communications Biology. 2020. 3. 1
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Shigefumi Morioka, Hirofumi Sakaguchi, Hiroaki Mohri, Mariko Taniguchi-Ikeda, Motoi Kanagawa, Toshiaki Suzuki, Yuko Miyagoe-Suzuki, Tatsushi Toda, Naoaki Saito, Takehiko Ueyama. Congenital hearing impairment associated with peripheral cochlear nerve dysmyelination in glycosylation-deficient muscular dystrophy. PLoS genetics. 2020. 16. 5. e1008826-e1008826
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Norio Motohashi, Akiyoshi Uezumi, Atsushi Asakura, Madoka Ikemoto-Uezumi, Shuuichi Mori, Yuhei Mizunoe, Rumi Takashima, Yuko Miyagoe-Suzuki, Shin'ichi Takeda, Kazuhiro Shigemoto. Tbx1 regulates inherited metabolic and myogenic abilities of progenitor cells derived from slow- and fast-type muscle. Cell death and differentiation. 2019. 26. 6. 1024-1036
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Fusako Sakai-Takemura, Asako Narita, Satoru Masuda, Toshifumi Wakamatsu, Nobuharu Watanabe, Takashi Nishiyama, Ken'Ichiro Nogami, Matthias Blanc, Shin'Ichi Takeda, Yuko Miyagoe-Suzuki. Premyogenic progenitors derived from human pluripotent stem cells expand in floating culture and differentiate into transplantable myogenic progenitors. Scientific Reports. 2018. 8. 1
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MISC (24)：
Patents (1)：
Books (9)：
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Mesenchymal Stem Cells for Regenerative Medicine for Duchenne Muscular Dystrophy
Intech 2020
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Muscle Cell and Tissue
2018
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Making skeletal muscle from human pluripotent stem cells.
2018
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Stem Cell-Based Therapy for Duchenne Muscular Dystrophy.
2016
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Translational Research in Muscular Dystrophy.
2016
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Lectures and oral presentations (71)：
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ヒト骨格筋前駆細胞の増殖と分化の制御機構の解明
(第18回日本再生医療学会総会 2019)
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ヒト骨格筋前駆細胞の増殖と分化の制御機構の解析
(第18回日本再生医療学会)
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ヒト人工多能性幹細胞から誘導される 骨格筋前駆細胞の増殖と分化制御機構の解析
(日本筋学会第4回学術集会)
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多能性幹細胞を用いた難治性筋疾患に対する細胞移植治療法の開発
(第17回日本再生医療学会総会 2018)
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ヒトiPS細胞を用いた難治性筋疾患に対する細胞移植治療法の開発.
(第39回国立精神・神経医療研究センター神経研究所 研究所発表会)
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Education (2)：
- - 1987 Kyushu University
- Kyushu University
Professional career (1)：
Association Membership(s) (3)：
日本筋学会
, THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE
, 日本分子生物学会
