Ichihashi Norikazu

イチハシノリカズ | Ichihashi Norikazu

Affiliation and department：
Job title： Professor

Research field (3)： Molecular biology , Biophysics , Evolutionary biology

Research keywords (4)：生命の起源と進化 , 生物物理 , 実験進化 , 合成生物学

Research theme for competitive and other funds (14)：

2020 - 2025 自己再生産し進化する人工ゲノム複製・転写・翻訳システムの開発
2022 - 2024 人工細胞システムを用いた核酸医薬合成に資するポリメレースの人為進化
2020 - 2022 Predict and regulate the evolvability from the fluctuation of RNA structure
2018 - 2020 人工RNA進化システムを用いたRNAの構造揺らぎと進化の関係の解析
2015 - 2020 Experimental evolution of an primitive cell model to understand possible evolutionary process

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Papers (101)：

Kensuke Ueda, Ryo Mizuuchi, Norikazu Ichihashi. Emergence of linkage between cooperative RNA replicators encoding replication and metabolic enzymes through experimental evolution. PLoS genetics. 2023. 19. 8. e1010471
Ryo Mizuuchi, Norikazu Ichihashi. Minimal RNA self-reproduction discovered from a random pool of oligomers. Chemical science. 2023. 14. 28. 7656-7664
Kaito Seo, Norikazu Ichihashi. Investigation of Compatibility between DNA Replication, Transcription, and Translation for in Vitro Central Dogma. ACS synthetic biology. 2023. 12. 6. 1813-1822
Kaito Seo, Katsumi Hagino, Norikazu Ichihashi. Progresses in Cell-Free In Vitro Evolution. Advances in biochemical engineering/biotechnology. 2023
Katsumi Hagino, Norikazu Ichihashi. In Vitro Transcription/Translation-Coupled DNA Replication through Partial Regeneration of 20 Aminoacyl-tRNA Synthetases. ACS synthetic biology. 2023. 12. 4. 1252-1263

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MISC (23)：

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Books (5)：

Lectures and oral presentations (39)：

Lessons from the In vitro construction of the “Central dogma”
(2023)
Evolution and regeneration of artificial cells
(Asian Synthetic Biology Association Workshop 2023)
進化実験が分子生態系を生み出した
(生命誌研究館 30周年公開シンポジウム 2023)
自律進化し自己増殖する分子システムの構築に向けて
(第6回分子サイバネティクス・第50回分子ロボティクス定例研究会 2023)
Development of diversity and ecological complexity in the experimental evolution of an RNA-protein replicator
(Molecular Origin of Life 2023 2023)

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Education (2)：

Work history (6)：

2019/01 - 現在 The University of Tokyo Graduate School of Arts and Sciences
2013/01 - 2018/12 Osaka University Graduate School of Information Science and Technology
2010/01 - 2013/06 Japan Science and Technology Agency
2008/04 - 2009/12 Osaka University Graduate School of Information Science and Technology
2006/04 - 2008/03 Japan Science and Technology Agency

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Committee career (3)：

Awards (2)：

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