Rchr
J-GLOBAL ID：200901096701976377
Update date: Sep. 24, 2024
Fukumoto Seiji
Fukumoto Seiji | Fukumoto Seiji
Affiliation and department：
Job title：
Project Professor
Research field (2)：
Nephrology
, Metabolism and endocrinology
Research keywords (6)：
CKD-MBD研究会
, rickets/osteomalacia
, phosphate metabolism
, FGF23
, Calcium-sensing receptor
, Endocrinology
Research theme for competitive and other funds (28)：
- 2022 - 2025 Research on phosphate-sensing mechanism that is essential for normal life expectancy
- 2019 - 2022 Study on the actions of phosphate as a first messenger
- 2016 - 2019 Role and mechanism of action of IL-11 on the regulation of bone and adipose tissue interaction
- 2015 - 2017 Exploration for the phosphate sensing mechanism of the body
- 2013 - 2016 Elucidation of molecular mechanism of the regulation of skeletal homeostasis, and development of new therapeutic approaches against skeletal disorders
- 2010 - 2012 Analyses of oxidative stress Mechanisms in bone mineral disorders
- 2009 - 2011 Regulatory mechanisms of mineral homeostasis by FGF23
- 2006 - 2008 Involvement of fibroblast growth factor 23 in bone and mineral metabolism and its disorders
- 2005 - 2006 Physiological and pathological involvement of FGF-23 in mineral metabolism in human
- 2003 - 2005 Research on regulatory mechanisms and their derangements of calcium and phosphate metabolism
- 2003 - 2004 Regulation by adipocytokines of bone metabolism
- 2001 - 2002 Role of bone marrow adipogenesis for bone formation and its abnormality in senile osteoporosis
- 2001 - 2002 Elucidetion of pathogeness of derangements in Calcinm metabolism
- 2000 - 2001 The mechanism of osteoblastic differentiotion regulated by BMP-dependent transcription factors-A basic study directed to development of a treatment for senile osteoporosis
- 1999 - 2000 Cell-matrix interaction in the regulation of bone metabolism and its disorder in involutional osteoporosis
- 1997 - 1998 Cell-matrix interaction in osteoblastic differentiation and its disorder in involutional osteoporosis
- 1997 - 1998 Research on signal transduction through parathyroid hormone(PTH)/PTH-related protein receptor
- 1995 - 1996 Regulation of osteoblastic differentiation and its implication in involutional osteoporosis
- 1995 - 1996 Molecular biological analysis of signal transduction system through parathyroid hormone receptor. Evaluation of parathyroid hormone receptor in patients with pseudohypoparathyroidism.
- 1994 - 1996 Development of a new therapeutic approach for senile osteoporosis using bone matrix deoorin
- 1994 - 1996 Role of matrix proteins in the local regulation of bone metabolism and its abonomalities in osteoporosis
- 1994 - 1994 偽性副甲状腺機能低下症患者における副甲状腺ホルモン受容変異の検討
- カルシウム感知受容体に関する研究
- 代謝性骨疾患に関する研究
- 副甲状腺ホルモン受容体に関する研究
- Study on calcium-sensing receptor
- Study on metabolic bone diseases
- Study on parathyroid hormone receptor
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Papers (278)：
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Toshimi Michigami, Hee Gyung Kang, Noriyuki Namba, Nobuaki Ito, Takuo Kubota, Ayumi Shintani, Daijiro Kabata, Masanori Kanematsu, Yayoi Nishida, Seiji Fukumoto, et al. Burosumab treatment of X-linked hypophosphatemia patients: interim analysis of the SUNFLOWER longitudinal, observational cohort study. JBMR plus. 2024. 8. 8. ziae079
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Yuichi Takashi, Daiji Kawanami, Seiji Fukumoto. Recent advances in fibroblast growth factor 23-related hypophosphatemic disorders. Current Opinion in Endocrinology, Diabetes & Obesity. 2024
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Yoshiya Tanaka, Satoshi Soen, Shintaro Hirata, Yosuke Okada, Saeko Fujiwara, Ikuko Tanaka, Yuriko Kitajima, Takuo Kubota, Kosuke Ebina, Yuichi Takashi, et al. The 2023 Guidelines for the management and treatment of glucocorticoid-induced osteoporosis. Journal of bone and mineral metabolism. 2024
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Sawatsubashi S, Takashi Y, Endo I, Kondo T, Abe M, Matsumoto T, Fukumoto S. Familial cases with adult-onset FGF23-related hypophosphatemic osteomalacia -A PHEX 3'-UTR change as a possible cause. Bone. 2024
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Yudai Joko, Yoko Yamamoto, Shigeaki Kato, Tatsuya Takemoto, Masahiro Abe, Toshio Matsumoto, Seiji Fukumoto, Shun Sawatsubashi. VDR is an essential regulator of hair follicle regression through the progression of cell death. Life science alliance. 2023. 6. 11
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MISC (245)：
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金本義明, 早川哲, 澤田崇広, 沢津橋俊, 福本誠二, 森甚一, 加藤茂明. カルシウム代謝調整因子群によるCYP24A1転写制御. ビタミン. 2022. 96. 4
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加藤茂明, 加藤茂明, 加藤茂明, 金本義明, 金本義明, 金本義明, 早川哲, 早川哲, 澤田崇広, 澤田崇広, et al. カルシウム代謝調整因子群によるCYP24A1転写制御. ビタミン. 2022. 96. 8
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金本義明, 金本義明, 沢津橋俊, 福本誠二, 加藤茂明, 加藤茂明, 加藤茂明. カルシウム代謝調整因子群によるCYP24A1転写制御. 日本骨代謝学会学術集会プログラム抄録集(CD-ROM). 2022. 40th
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沢津橋俊, 沢津橋俊, 池戸葵, 松本俊夫, 今井祐記, 福本誠二, 福本誠二. ヒト疾患型点変異を導入したビタミンD依存性くる病/骨軟化症モデルマウスの機能解析. 日本骨代謝学会学術集会プログラム抄録集(CD-ROM). 2022. 40th
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西村耕一, 西村耕一, 沢津橋俊, 松本俊夫, 福本誠二. SWI/SNF複合体のIDRによる相分離を介した核内受容体AF-1領域との相互作用解析. 日本生化学会大会(Web). 2021. 94th
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Books (7)：
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Klotho - the discovery of the FGF23 coreceptor
Elsevier 2021
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The Bone-FGF23-Klotho Axis and Associated Diseases
Academic Press 2020
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Fibroblast growth factor 23
Academic Press 2019
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Phosphate Metabolism, Hyperphosphatemia, and Hypophosphatemia
Academic Press 2018
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薬を飲んでも血圧が下がりません
Nankodo 2017
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Lectures and oral presentations (140)：
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低Mg血症によるPTH分泌不全により著明な低Ca血症を来した一例
(第33回日本老年医学会四国地方会 2022)
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レンバチニブで破壊性甲状腺炎をきたし,医原性副腎皮質機能低下症による副腎不全が顕在化した一例
(日本内科学会 第125回 四国地方会 2021)
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1型糖尿病とバセドウ病を同時に診断した1例
(日本内科学会 第125回 四国地方会 2021)
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アルドステロンを含む3種のホルモン産生副腎皮質癌の一例
(第32回臨床内分泌代謝Update 2021)
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10cmの右大腿部腫瘤を原因とする腫瘍性骨軟化症の1例
(第31回臨床内分泌Update 2021)
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Education (2)：
- - 1990 The University of Tokyo
- - 1982 The University of Tokyo Faculty of Medicine School of Medicine
Professional career (1)：
- MD, PhD (The University of Tokyo)
Awards (5)：
- 2013/05/30 - Japanese Society for Bone and Mineral Research 尾形賞
- 2003/04 - 東京大学医師会医学賞
- 2002/06/28 - The Japan Endocrine Society 研究奨励賞
- 2001/08/10 - Japanese Society for Bone and Mineral Research 学術賞
- 1988/07 - 日本骨代謝学会奨励賞
Association Membership(s) (9)：
日本腎臓学会
, 日本骨粗鬆症学会
, 米国内分泌学会(American Endocrine Society)
, 日本糖尿病学会
, 日本内分泌学会
, 日本内科学会
, 日本骨代謝学会
, 日本癌学会
, 米国骨・ミネラル学会(American Society for Bone and Mineral Research)
