Research theme for competitive and other funds (17)：
2023 - 2026 高齢者疲労感の病態解明を目的とした漢方「補剤」の作用機序研究
2021 - 2025 Prevention of impaired cognitive function by food factors
2009 - 2011 PPARγplays an important role in improvement of cognitive decline in Alzheimer's disease model animals complicated by lifestyle deseases.
2008 - 2010 Study for regeneration of function in neonatal hypoxic-ischemic encephalopathy using animal model of slowly progressive brain damage in rats
2008 - 2008 ガングリオシド欠損によるコルチ器崩壊の分子機構の解明
2007 - 2008 Pharmacological studies in accelerating mechanism of Alzheimer's disease by diabetes mellitus with insulin resistance in rats
2006 - 2007 Study on impaired social interaction in cannabis-treated and psychiatric animals
2005 - 2006 Investigation of cerebral paralysis and its development of new drugs in neonatal hypoxic-ischemia-induced slowly progressive brain damage
2005 - 2006 Pharmacological studies in the animal model for Alzheimer' s disease with life-style related disease
2004 - 2005 Investigation of mechanisms mediating pubertal treatment of marihuana-induced psychosis
2001 - 2005 アルツハイマー病の成因と治療薬開発に関する共同研究
2002 - 2004 Hypoxia-ischemic insult in neonatal rats induced slowly progressive brain damage related to memory impairment and its development of new drugs.
2001 - 2003 Molecular pharmacological studies in the animal model for Alzheimer's disease
1994 - 1995 Disruption of spatial cognition following repeated-ischemia in radial arm maze and improvemental effect of radical scavengers
1992 - 1992 脳虚血によるラットの認知記憶障害と遅発性神経細胞壊死
1991 - 1991 脳虚血による空間認知障害の発現メカニズムと神経伝達物質動態
1986 - 1986 大麻にによる異常行動発現機構に関する神経化学的研究
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Papers (343)：
Akinobu Hatae, Takuya Watanabe, Chise Taniguchi, Kaori Kubota, Shutaro Katsurabayashi, Katsunori Iwasaki. Ninjinyoeito ameliorates anorexia and changes in peptide YY and ghrelin levels of cisplatin-treated mice. Neuropeptides. 2024. 107. 102464-102464
Otoya Kitaoka, Kohei Oyabu, Kaori Kubota, Takuya Watanabe, Satoru Kondo, Teppei Matsui, Shutaro Katsurabayashi, Katsunori Iwasaki. Location analysis of presynaptically active and silent synapses in single-cultured hippocampal neurons. 2023
Masaki Nagao, Akinobu Hatae, Kazuma Mine, Soichiro Tsutsumi, Hiroya Omori, Marika Hirata, Maaya Arimatsu, Chise Taniguchi, Takuya Watanabe, Kaori Kubota, et al. The Effects of Ninjinyoeito on Impaired Spatial Memory and Prefrontal Cortical Synaptic Plasticity through α-Amino-3-hydroxy-5-4-isoxazole Propionic Acid Receptor Subunit in a Rat Model with Cerebral Ischemia and β-Amyloid Injection. Evidence-Based Complementary and Alternative Medicine. 2023. 2023. 1-10
Chise Taniguchi, Takuya Watanabe, Marika Hirata, Akinobu Hatae, Kaori Kubota, Shutaro Katsurabayashi, Katsunori Iwasaki. Ninjinyoeito Prevents Onset of Depression-Like Behavior and Reduces Hippocampal iNOS Expression in Senescence-Accelerated Mouse Prone 8 Mice. Evidence-Based Complementary and Alternative Medicine. 2023. 2023. 1-9
- 1985 Kyushu University Graduate School, Division of Pharmaceutical Sciences Pharmacology
- 1980 Kumamoto University Faculty of Pharmaceutical Science Pharmaceutical Chemistry
Professional career (2)：
薬学博士 (九州大学)
Doctor (ph D) (Kyushu University)
Work history (5)：
2006 - 現在 現在 福岡大学薬学部 教授 教授
2019/12 - 2023/11 福岡大学大学院薬学研究科長
2011/04/01 - Institute of Aging and Brain Sciences 所長
2000 - 2006 福岡大学薬学部 助教授
1985 - 2000 Research Associate, Faculty of Pharmaceutical Sciences, Fukuoka University 助手
Awards (3)：
2019/08/31 - 和漢医薬学会 和漢医薬学会賞
2017/02/05 - イスクラ技術交流基金 漢方研究イスクラ奨励賞
1993/03/20 - Yuichi Yamamura Award for WAKANYAKU
Association Membership(s) (9)：
日本脳循環代謝学会
, 日本東洋医学会
, 日本神経科学会
, Neuroscience Meeting
, Medical and Pharmaceutical Society for WAKAN-YAKU
, Japanese Society for Neurochemistry
, The Japanese Society of Neuropharmacology (JSNP)
, The Pharmaceutical Society of Japan
, The Japanese Pharmacological Society
