Rchr
J-GLOBAL ID：200901096985673344
Update date: Sep. 25, 2024
Ito Hidenori
イトウ ヒデノリ | Ito Hidenori
Affiliation and department：
Job title：
室長
Research field (5)：
Neuroscience - general
, Pharmacology
, Pharmaceuticals - health and biochemistry
, Cell biology
, Molecular biology
Research keywords (9)：
神経科学
, シナプス
, 海馬
, 発達障害
, 低分子量Gタンパク質
, crystallin
, phosphorylation
, stress proteins
, stress response
Research theme for competitive and other funds (28)：
- 2019 - 2022 Neurodevelopmental disorder related Rac signaling pathways control the neonatal development of the dentate gyrus
- 2016 - 2019 歯状回神経細胞の発達における知的障害・精神疾患関連Rhoシグナル伝達系の機能解明
- 2011 - 2015 統合失調症発症脆弱性因子dysbindin-1による細胞機能制御
- 2011 - 2012 Analyses of pathophysiology for molecules causing mental retardation
- 2009 - 2012 Septin functions and autistic spectrum disorder/pervasive developmental disorders during neuronal development
- 2009 - 2011 統合失調症関連分子dysbindin-1の性状機能解析
- 2007 - 2009 セプチン結合タンパク質の探索と性状・機能解析
- 2007 - 2009 Analysis of molecular and cellular targets in neurotoxicity of alternatives to ozone-depleting substances and establishment of biomarkers for the central nervous toxicity
- 2005 - 2007 セプチンの細胞内動態を制御する分子の探索と機能解析
- 2006 - 2007 Sept8をモデルとした新奇G蛋白質セプチンの性状・機能解析
- 2003 - 2005 低分子量分子シャペロンと相互作用する蛋白質の解析
- 2003 - 2004 Small Ubiquitin-related Modifier is Involved in Regulatory Mechanisms of DNA Repair and/or Gene Expression in Pancreatic Acinar Cells.
- 2001 - 2003 ユビキチン/プロテアソーム系とαBクリスタリンの細胞内動態の関連について
- 2003 - 2003 分子シャペロン、Hsp27とαBクリスタリンの細胞内蛋白質品質管理に果たす役割
- 2000 - 2003 Studies on α crystallin small molecular chaperones
- 2002 - 2002 分子シャペロン、Hsp27とαBクリスタリンの細胞内蛋白質品質管理に果たす役割
- 2002 - 2002 アグリソームの構成成分であるαBクリスタリンとHsp27の生理的・病理的意義
- 2001 - 2002 αBクリスタリンの神経組織蓄積機構の解明
- 2001 - 2002 Roles of Small Ubiquitin-related Modifier in Pancreatic Acinar Cells.
- 1999 - 2001 細胞内および動物組織におけるαBクリスタリンのリン酸化の生理的意義の解明
- 2001 - 2001 Aggresomeの構成成分であるリン酸化αBクリスタリンの生理的・病理的意義
- 2000 - 2000 脳の老化に伴って脳に沈着する分子シャペロンの生理的・病理的意義
- 2000 - 2000 神経組織での低分子量分子シャペロンのストレス応答と生理的意義
- 1999 - 1999 神経組織での低分子量分子シャペロンのストレス応答と生理的意義
- 1998 - 1998 神経障害時の低分子量分子シャペロンの応答と生理的意義
- 1998 - 1998 αBクリスタリンのリン酸化とその生理的意義
- 1994 - 1996 Research on the mammalian small stress protein family
- Elucidation of physiological function of phosphorylated small heat shock proteins
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Papers (130)：
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Masashi Nishikawa, Shin Hayashi, Atsushi Nakayama, Yosuke Nishio, Anna Shiraki, Hidenori Ito, Kouichi Maruyama, Yukako Muramatsu, Tomoo Ogi, Seiji Mizuno, et al. Pathophysiological significance of the p.E31G variant in RAC1 responsible for a neurodevelopmental disorder with microcephaly. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 2024. 167520-167520
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Tomoki Ishiguro, Mariko Noda, Masashi Nishikawa, Koh-ichi Nagata, Hidenori Ito. Variations associated with neurodevelopmental disorders affect ARF1 function and cortical development. The Journal of Biochemistry. 2024
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Tohru Matsuki, Nanako Hamada, Hidenori Ito, Ryota Sugawara, Ikuko Iwamoto, Atsuo Nakayama, Koh-Ichi Nagata. Expression analysis of type I ARF small GTPases ARF1-3 during mouse brain development. Molecular biology reports. 2024. 51. 1. 106-106
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Masashi Nishikawa, Tohru Matsuki, Nanako Hamada, Atsuo Nakayama, Hidenori Ito, Koh-ichi Nagata. Expression analyses of WAC, a responsible gene for neurodevelopmental disorders, during mouse brain development. Medical Molecular Morphology. 2023
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Rie Seyama, Masashi Nishikawa, Yuri Uchiyama, Keisuke Hamada, Yuka Yamamoto, Masahiro Takeda, Takanori Ochi, Monami Kishi, Toshifumi Suzuki, Kohei Hamanaka, et al. A missense variant at the RAC1-PAK1 binding site of RAC1 inactivates downstream signaling in VACTERL association. Scientific Reports. 2023. 13. 1
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MISC (29)：
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Y. Mizutani, H. Ito, I. Iwamoto, R. Morishita, H. Kanoh, M. Seishima, K. Nagata. A septin, SEPT1, is involved in cell spreading of squamaous cell carcinoma DJM-1 cells. JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2012. 132. S46-S46
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H. Ito, R. Morishita, T. Shinoda, I. Iwamoto, K. Sudo, K. Nagata. SCHIZOPHRENIA SUSCEPTIBILITY GENE, DYSBINDIN-1, REGULATES THE DENDRITIC SPINE FORMATION: EVIDENCE SUPPORTING NEURODEVELOPMENTAL HYPOTHESIS. JOURNAL OF NEUROCHEMISTRY. 2010. 115. 15-15
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H. Ito, K. Atsuzawa, R. Morishita, N. Usuda, K. Sudo, I. Iwamoto, K. Mizutani, R. Katoh-Semba, Y. Nozawa, T. Asano, et al. Sept8 controls the binding of vesicle-associated membrane protein 2 to synaptophysin. (vol 108, pg 867, 2009). JOURNAL OF NEUROCHEMISTRY. 2009. 108. 6. 1621-1621
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BANU Shameema. REVERSIBILITY OF THE ADVERSE EFFECTS OF 1-BROMOPROPANE EXPOSURE IN MALE RATS. 2007. 62. 2. 472-472
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Ito Hidenori, Usuda Nobuteru, Atsuzawa Kimie, Iwamoto Ikuko, Sudo Kaori, Katoh-Semba Ritsuko, Mizutani Kosuke, Morishita Rika, Deguchi Takashi, Nozawa Yoshinori, et al. P2-19 Phosphorylation by MAP kinase of a Multi-Domain Adaptor Protein, Vinexin, in Neurons :. 2007. 48. 124-124
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Education (2)：
- - 1994 Nagoya City University
- - 1992 Nagoya City University Medicin
Professional career (1)：
Work history (4)：
- 2017/04 - 現在 愛知県心身障害者コロニー 発達障害研究所 室長
- 2008 - Institute for Developmental Research, Aichi Human Service Center
- 1998 - Institute for Developmental Research, Aichi Human Service Center
- 1994 - Institute for Developmental Research, Aichi Human Service Center
Association Membership(s) (2)：
THE JAPANESE SOCIETY FOR CLINICAL MOLECULAR MORPHOLOGY
, 日本生化学会
