Research theme for competitive and other funds (27):
2023 - 2028 Science for Boundary Lubrication - Essence of Low Friction Mechanism Based on Structure and Dynamics of Additive Adsorption Layer
2021 - 2024 深海模倣系構築による高圧下の蛋白質構造の実測法の開発
2020 - 2023 分子混雑環境下におけるクリスタリンの構造解析
2019 - 2023 量子ビーム相関解析法による生体高分子構造・ダイナミクスの探求
2018 - 2023 ヌクレオソーム高次構造とダイナミクスの解析によるクロマチン潜在能の解明
2018 - 2023 Neutron Structural Biology for New Generation
2018 - 2019 細胞再現系での蛋白質の構造・ダイナミクスの解明
2016 - 2018 量子ビーム散乱法の協奏的利用による機能性ヌクレオソームの溶液構造解析
2016 - 2018 巨大タンパク質会合体における動的ネットワークとその機能解明
2015 - 2018 Mechanism of sugar chain elongation catalyzed by muscular dystrophy cause gene product LARGE
2015 - 2018 Development of Analysis Method for Reconbinant Biomacromolecular System utlizing Neutron Scattering
2014 - 2016 CV-SANS法による変異型ヌクレオソームの詳細構造解析
2014 - 2016 生体分子集合体が形成する動的平衡の中性子小角散乱による研究
2014 - 2016 Formation of nanostructure of food plant proteins
2012 - 2015 Development of analysis method for dynamic state in high order structure of protein utilizing neutron scattering
2012 - 2014 重水素化中性子小角散乱を用いた天然変性タンパク質による揺らぎ構造の解析
2011 - 2014 Development of fabrication technique for a two-dimensional neutron focusing mirror and the performance test
2008 - 2012 Mechanism of abnormal protein aggregation and the study of the repair enzyme.
2009 - 2011 Analysis for Dynamics on High Order Structure of Protein
1999 - 2010 ソフトマターの構造研究
1999 - 2010 Structural Investigation on Soft Matter
2007 - 2008 Study on Mechanism of Formation of High-Order Structure of Protein
2007 - 2008 Studies on structures and electric field effects in liquid crystalline soft matters
2006 - 2008 Structural study of Parkinson disease related protein by intermediate region neutron scattering method
2004 - 2005 ヘテロ高分子の構造転移に伴う疎水性水和水の動的構造の変化
2001 - 2002 ACカロリメーター比熱測定による生体高分子の協同的立体構造変調の研究
1996 - 1996 中性子小角散乱法による多糖類電解質高分子のゾル-ゲル転移の観測
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Papers (213):
R. Inoue, Y. Nagata, T. Tominaga, S. Sato, Y. Kawakita, T. Yamawaki, K. Morishima, M. Suginome, M. Sugiyama. Dynamics of side chains in poly(quinoxaline-2,3-diyl)s studied via quasielastic neutron scattering. The Journal of Chemical Physics. 2024. 161. 5
Honoka Kawamukai, Motonori Matsusaki, Takanari Tanimoto, Mai Watabe, Ken Morishima, Shunsuke Tomita, Yoichi Shinkai, Tatsuya Niwa, Taro Mannen, Hiroyuki Kumeta, et al. Conserved loop of a phase modifier endows protein condensates with fluidity. bioRxiv. 2024
Jiayue Sun, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Takumi Takata. Characterization of βB2-crystallin tryptophan mutants reveals two different folding states in solution. Protein Science. 2024. 33. 7
Masahiro Nishimura, Takeru Fujii, Hiroki Tanaka, Kazumitsu Maehara, Ken Morishima, Masahiro Shimizu, Yuki Kobayashi, Kayo Nozawa, Yoshimasa Takizawa, Masaaki Sugiyama, et al. Genome-wide mapping and cryo-EM structural analyses of the overlapping tri-nucleosome composed of hexasome-hexasome-octasome moieties. Communications Biology. 2024. 7. 1
Keisuke Yuzu, Hiroshi Imamura, Takuro Nozaki, Yuki Fujii, Shaymaa Mohamed Mohamed Badawy, Ken Morishima, Aya Okuda, Rintaro Inoue, Masaaki Sugiyama, Eri Chatani. Mechanistic modeling of amyloid oligomer and protofibril formation in bovine insulin. Journal of Molecular Biology. 2024. 168461-168461
小田隆, 小田隆, 井上倫太郎, 守島健, 會澤直樹, 富永大輝, 中川洋, 大井里香, 石野園子, 石野良純, et al. Analysis of structure and dynamics of multidomain protein Hef by X-ray/neutron scattering. 量子ビームサイエンスフェスタ(Web). 2024. 2023
CHATAKE T., OKODA A., MORISHIMA K., INOUE R., SUGIYAMA M., TAKATA T., YANAGISAWA Y. Analysis of water-soluble vitamin K complex from Bacillus subtilis natto. KURNS Progress Report (Web). 2023. 2022