Ono Kenji

オノケンジ | Ono Kenji

Affiliation and department：
Other affiliations (1)：

Nagoya City University Institute of Brain Life Sciences

Research field (1)： Neuroscience - general

Research keywords (8)： Signal peptides , Demyelination , Glia , Extracellular vesicles , Imaging , Drug Delivery System , Microglia , Bone Marrow Transplantation

Research theme for competitive and other funds (12)：

2024 - 2027 Biosynthesis and physiological functions of extracellular vesicles containing signal peptides.
2020 - 2023 グリア前駆細胞から放出される細胞外小胞を介した再ミエリン化の分子機構解明
2019 - 2022 Role of diabetes and inflammation on microglial cell biology and transformation
2018 - シグナルペプチド:細胞外微粒子機能の新規マーカー
2015 - 2018 Optogenetic control of differentiation into oligodendrocytes

Show all

Papers (38)：

Jeladhara Sobhanan, Kenji Ono, Takuya Okamoto, Makoto Sawada, Paul S Weiss, Vasudevanpillai Biju. Photosensitizer-singlet oxygen sensor conjugated silica nanoparticles for photodynamic therapy and bioimaging. Chemical science. 2024. 15. 6. 2007-2018
Kenji Ono, Junpei Sato, Hiromi Suzuki, Makoto Sawada. Distribution of Signal Peptides in Microvesicles from Activated Macrophage Cells. International Journal of Molecular Sciences. 2023. 24. 15. 12131
Kenji Ono, Mikio Niwa, Hiromi Suzuki, Nahoko Bailey Kobayashi, Tetsuhiko Yoshida, Makoto Sawada. Calmodulin as a Key Regulator of Exosomal Signal Peptides. Cells. 2022. 12. 1. 158
Kenji Ono, Mikio Niwa, Hiromi Suzuki, Nahoko Bailey Kobayashi, Tetsuhiko Yoshida, Makoto Sawada. Signal Sequence-Dependent Orientation of Signal Peptide Fragments to Exosomes. International Journal of Molecular Sciences. 2022. 23. 6. 3137
Naoki Yoshioka, Miyako Tanaka, Kozue Ochi, Akiko Watanabe, Kenji Ono, Makoto Sawada, Tomoo Ogi, Michiko Itoh, Ayaka Ito, Yukihiro Shiraki, et al. The sodium-glucose cotransporter-2 inhibitor Tofogliflozin prevents the progression of nonalcoholic steatohepatitis-associated liver tumors in a novel murine model. Biomedicine & Pharmacotherapy. 2021. 140. 111738-111738

ｍore...

MISC (38)：

Yudai Takatani, Kenji Ono, Hiromi Suzuki, Masato Inaba, Makoto Sawada, Naoyuki Matsuda. Inducible nitric oxide synthase during the late phase of sepsis is associated with hypothermia and immune cell migration. Laboratory Investigation. 2018. 98. 5. 629-639
Qi Wu, Kenji Ono, Hiromi Suzuki, Megumi Eguchi, Shun Yamaguchi, Makoto Sawada. Visualization of Arc promoter-driven neuronal activity by magnetic resonance imaging. Neuroscience Letters. 2018. 666. 92-97
Michiko Oya, Hiromi Suzuki, Andrea Roxanne J. Anas, Koichi Oishi, Kenji Ono, Shun Yamaguchi, Megumi Eguchi, Makoto Sawada. LC-MS/MS imaging with thermal film-based laser microdissection. Analytical and Bioanalytical Chemistry. 2018. 410. 2. 491-499
Hsiaoyun Lin, Rieko Muramatsu, Noriko Maedera, Hiroto Tsunematsu, Machika Hamaguchi, Yoshihisa Koyama, Mariko Kuroda, Kenji Ono, Makoto Sawada, Toshihide Yamashita. Extracellular Lactate Dehydrogenase A Release From Damaged Neurons Drives Central Nervous System Angiogenesis. EBioMedicine. 2018. 27. 71-85-85
Kenji Ono, Hiromi Suzuki, Ryusei Yamamoto, Hideki Sahashi, Yuhei Takido, Makoto Sawada. Optogenetic control of cell differentiation in channelrhodopsin-2-expressing OS3, a bipotential glial progenitor cell line. NEUROCHEMISTRY INTERNATIONAL. 2017. 104. 49-63

ｍore...

Patents (9)：

質量分析方法
質量分析方法
レーザマイクロダイセクション装置
蛍光プローブ及びその製造方法
蛍光プローブ及びその製造方法

ｍore...

Books (1)：

Etiology and Pathophysiology of Parkinson's Disease, Role of microglia in inflammatory process in Parkinson's disease.
InTech 2011 ISBN:9789533074627

Lectures and oral presentations (81)：

Distribution of Signal Peptides in Extracellular Vesicles from Activated Macrophage Cells
(The 97th Annual Meeting of the Japanese Biochemical Society 2024)
新規COX-2阻害剤によるミクログリアの活性化抑制とドーパミン神経への保護作用
(第46回日本分子生物学会年会 2023)
Calmodulin as a key regulator of exosomal signal peptides
(The 96th Annual Meeting of the Japanese Biochemical Society 2023)
Effect of exosomal miR-155-5p from glial progenitor cells in microglial polarization at the demyelinated area
(The 46th Annual Meeting of the Japan Neuroscience Society 2023)
Detection of activated microglia by mass spectrometry imaging
(2022)

ｍore...

Works (12)：

名大トピックス No.229 知の未来へー若手研究者の紹介「光感受性イオンチャネルを用いた細胞機能の光制御」
2012 - 2012
Control of activation in ChR2-expressing astrocytes by blue light exposure. Neurosci Res 68: e57
2010 - 2010
Protective roles of brain-migrated immature bone marrow cells against NO-dependent neurotoxicity in a brain injury model. Neurosci Res 65: S43
2009 - 2009
Expression of cytokines and neurotrophins after acute subarachnoid hemorrhage. Stroke 39(2): 650
2008 - 2008
Enhancement of glioma formation and growth by brain-migrated immature bone marrow cells. Neurosci Res 61: S276
2008 - 2008

ｍore...

Education (3)：

2000 - 2003 Doctor’s Program, Graduate School of Pharmaceutical Sciences, Nagoya City University
1998 - 2000 Master's Program, Graduate School of Pharmaceutical Sciences, Nagoya City University
1994 - 1998 Department of Pharmacy, Faculty of Pharmaceutical Sciences, Nagoya City University

Professional career (2)：

Doctor (Pharmaceutical Science) (Nagoya City University)
Master (Pharmaceutical Science) (Nagoya City University)

Work history (6)：

2024/07 - 現在 Department of Neurotoxicology, Graduate School of Medical Sciences and Medical School, Nagoya City University Associate professor
2013/04 - 2024/06 Assistant Professor, Molecular Pharmacokinetics, Nagoya University Graduate School of Medicine Assistant Professor
2007/04 - 2024/06 Assistant Professor, Department of Brain Functions, Division of Stress Adaptation and Protection, Research Institute of Environmental Medicine, Nagoya University Assistant professor
2005/04 - 2007/03 Assistant Professor, Department of Brain Life Science, Division of Higher Nervous Control, Research Institute of Environmental Medicine, Nagoya University
2004/04/01 - 2005/03/31 Research Associate, Joint Research Division for Therapies against Intractable Diseases, Institute for Comprehensive Medical Science, Fujita Health University

Show all

Association Membership(s) (3)：

日本神経科学学会 , The Japanese Society for Neurochemistry , The Japanese Biochemical Society

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page