Rchr
J-GLOBAL ID：200901099432162669   Update date: Feb. 14, 2024

KUROYANAGI Hidehito

クロヤナギ ヒデヒト | KUROYANAGI Hidehito
Affiliation and department：
University of the Ryukyus Graduate School of Medicine

About University of the Ryukyus Graduate School of Medicine


Job title： Professor
Homepage URL  (2)： https://biochem.med.u-ryukyu.ac.jp/ ,  https://biochem.med.u-ryukyu.ac.jp/en/
Research field  (1)： Molecular biology
Research keywords  (17)： リボソーム ,  次世代シーケンサー ,  分子遺伝学 ,  変異体 ,  トランスクリプトーム ,  可視化 ,  モデル生物 ,  nuclear export ,  bioinformatics ,  transcriptome ,  model organism ,  gene expression ,  development ,  C. elegans ,  reporter ,  genetics ,  alternative splicing
Research theme for competitive and other funds  (30)：
  • 2023 - 2025 Elucidation of pathogenesis mechanisms and exploration of therapeutic strategies using mouse models of dilated cardiomyopathy
  • 2020 - 2023 Tissue-specific pre-mRNA processing in living animals
  • 2020 - 2023 疾患特異的スプライシングバリアントをターゲットにした乳がん治療・診断法の確立
  • 2020 - 2021 Nutrition signals and gene expression networks to launch larval development in nematodes
  • 2020 - 2021 Functional Analysis of RBM20 Whose Mutation Causes Dilated Cardiomyopathy
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Papers (56)：
  • Hirotatsu Imai, Daisuke Utsumi, Hidetsugu Torihara, Kenzo Takahashi, Hidehito Kuroyanagi, Akio Yamashita. Simultaneous measurement of nascent transcriptome and translatome using 4-thiouridine metabolic RNA labeling and translating ribosome affinity purification. Nucleic Acids Research. 2023
  • Jue Ju, Tomohiko Aoyama, Yuka Yashiro, Seisuke Yamashita, Hidehito Kuroyanagi, Kozo Tomita. Structure of the Caenorhabditis elegans m6A methyltransferase METT10 that regulates SAM homeostasis. Nucleic Acids Research. 2023
  • Hirotatsu Imai, Daisuke Utsumi, Hidetsugu Torihara, Kenzo Takahashi, Hidehito Kuroyanagi, Akio Yamashita. Simultaneous measurement of nascent transcriptome and translatome using 4-thiouridine metabolic RNA labeling and translating ribosome affinity purification. 2023
  • Tatsuya Fujikawa, Fumihiro Sanada, Yoshiaki Taniyama, Kana Shibata, Naruto Katsuragi, Nobutaka Koibuchi, Kaori Akazawa, Yuko Kanemoto, Hidehito Kuroyanagi, Kenzo Shimazu, et al. Periostin Exon-21 Antibody Neutralization of Triple-Negative Breast Cancer Cell-Derived Periostin Regulates Tumor-Associated Macrophage Polarization and Angiogenesis. Cancers. 2021. 13. 20. 5072-5072
  • Tatsuya Fujikawa, Fumihiro Sanada, Yoshiaki Taniyama, Kana Shibata, Naruto Katsuragi, Nobutaka Koibuchi, Kaori Akazawa, Yuko Kanemoto, Hidehito KUROYANAGI, Kenzo Shimazu, et al. Periostin Exon-21 Antibody Neutralization of Triple-Negative Breast Cancer Cell-Derived Periostin Regulates Tumor-Associated Macrophage Polarization and Angiogenesis. Cancers. 2021
ｍore...
MISC (14)：
  • Josh Arribere, Hidehito Kuroyanagi, Heather Hundley. mRNA Editing, Processing and Quality Control in Caenorhabditis elegans. Genetics. 2020. 215. 3. 531-568
  • Dawn Elizabeth Barnes, Hidehito Kuroyanagi, Kanako Ono, Euiyoung (Tommy) Kwak, Shoichiro Ono. A Novel Alternative Exon of the Caenorhabditis Elegans Lev-11 Tropomyosin Gene is used to Express a Head-Muscle-Specific Isoform. FASEB JOURNAL. 2016. 30
  • Dawn Elizabeth Barnes, Hidehito Kuroyanagi, Kanako Ono, Euiyoung (Tommy) Kwak, Shoichiro Ono. A Novel Alternative Exon of the Caenorhabditis Elegans Lev-11 Tropomyosin Gene is used to Express a Head-Muscle-Specific Isoform. FASEB JOURNAL. 2016. 30
  • 桑迫香奈子, 高橋真梨, 黒柳秀人, 武藤 裕. 組織特異的にスプライシング反応を制御するRBFOXファミリーRNA結合タンパク質およびSUP-12によるRNAの協働的な認識の機構. ライフサイエンス 新着論文レビュー. 2014
  • Hidehito Kuroyanagi. Genetic analyses of alternative pre-mRNA processing in C. elegans. GENES & GENETIC SYSTEMS. 2013. 88. 6. 336-336
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Books (5)：
  • 遺伝学の百科事典(仮)
    丸善出版株式会社 2020
  • 遺伝子発現制御機構 -クロマチン,転写制御,エピジェネティクス-
    株式会社 東京化学同人 2017 ISBN:9784807909179
  • ノンコーディングRNA -RNA分子の全体像を俯瞰する-
    株式会社 化学同人 2016 ISBN:9784759817256
  • Alternative pre-mRNA Splicing: Theory and Protocols
    Wiley-VCH 2012 ISBN:9783527326068
  • キーワードで理解する 転写イラストマップ
    2004 ISBN:9784897065793
Lectures and oral presentations  (38)：
  • Alternative splicing through m6A modification at a 3' splice site for SAM synthetase homeostasis
    (第2回RNAJオンラインミーティング「mRNA/miRNAの代謝」 2020)
  • Homeostasis of S-adenosylmethionine (SAM) synthetase genes in C. elegans by alternative pre-mRNA splicing through m6A modification at the 3' spice site
    (第42回日本分子生物学会年会 2019)
  • Analysis of RBM20 mutations associated with dilated cardiomyopathy
    (2019)
  • Alternative splicing regulation of the S-adenosylmethionine synthase (sams) genes through adenosine methylation at their 3’ splice sites
    (線虫研究の未来を創る会 2019 2019)
  • Nascent RNA sequencing reveals pre-mRNA processing dynamics governed by splicing regulators
    (線虫研究の未来を創る会 2019 2019)
ｍore...
Works (4)：
  • Cytoskeleton. Cover Image, Volume 75, Issue 10
    Eichi Watabe, Shoichiro Ono, Hidehito Kuroyanagi 2018 -
  • Molecular and Cellular Biology. Cover Image, Volume 28, Issue 14
    Hidehito Kuroyanagi, Genta Ohno, Shohei Mitani, Masatoshi Hagiwara 2008 -
  • Genes & Development. Cover Image, Volume 22, Issue 3
    Ohno G, Hagiwara M, Kuroyanagi H 2008 -
  • Nature Methods. Cover Image, Volume 3, Issue 11
    Hidehito Kuroyanagi, Tetsuo Kobayashi, Shohei Mitani, Masatoshi Hagiwara 2006 -
Education (2)：
  • 1994 - 1999 The University of Tokyo Graduate School, Division of Science
  • 1989 - 1994 The University of Tokyo Faculty of Science
Professional career (1)：
  • Dr. Sci (The University of Tokyo)
Work history (11)：
  • 2021/05/01 - 現在 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Medical and Dental Sciences - - Visiting Lecturer
  • 2012/04/01 - 2021/03/31 Tokyo Medical and Dental University Medical Research Institute Medical Genomics Associate Professor
  • 2020/08 - 2021/03 Tokyo Medical and Dental University Medical Hospital
  • 2019/10 - 2021/03 Tokyo Medical and Dental University -
  • 2017/03/01 - 2018/07/31 University of California, Los Angeles (UCLA) Department of Microbiology, Immunology and Molecular Genetics (MIMG) Visiting Associate Professor
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Committee career (8)：
  • 2020/04 - 2022/03 日本RNA学会 第11期評議員
  • 2018/04 - 2020/03 日本RNA学会 第10期評議員
  • 2017/12 - 2018/11 独立行政法人日本学術振興会 科学研究費委員会専門委員
  • 2016/04 - 2018/03 日本RNA学会 第9期評議員
  • 2012/08 - 2017/03 文部科学省科学技術政策研究所科学技術動向研究センター 専門調査員
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Awards (4)：
  • 2014/10 - 東京医科歯科大学 東京医科歯科大学優秀研究賞
  • 2009/04 - 文部科学大臣 平成21年度科学技術分野の文部科学大臣表彰若手科学者賞 生体内可視化技術の開発によるスプライシング暗号の研究
  • 2008/02 - 東京医科歯科大学難治疾患研究所 2007年難治疾患研究所優秀論文賞
  • 2007/02 - 東京医科歯科大学難治疾患研究所 2006年難治疾患研究所優秀論文賞
Association Membership(s) (6)：
日本分子生物学会 ,  日本神経科学学会 ,  日本RNA学会 ,  日本ケミカルバイオロジー学会 ,  Genetics Society of America ,  The RNA Society
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