Research theme for competitive and other funds (6)：
2005 - 2007 mechanism of psoriasis Neuropeptides and inflammatory cytokines enhance vascular endotherial growth factor production from epidermal keratinocytes
2002 - 2002 アトピー性皮膚炎増悪のメカニズム
2000 - 2001 神経ペプチドレセプターのアトピー性皮膚炎の病態への関与
接触皮膚炎の神経伸長におけるマスト細胞の役割
アトピー性皮膚炎の表皮における神経ペプチドとその病因的役割
Expression of vasoactive intestinal peptide on the epidermis in patients with atopic dermatitis
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Papers (23)：
Naoka Umemoto, Maki Kakurai, Takanao Matsumoto, Kenta Mizuno, Otomi Cho, Takashi Sugita, Toshio Demitsu. Dupilumab Alters Both the Bacterial and Fungal Skin Microbiomes of Patients with Atopic Dermatitis. Microorganisms. 2024. 12. 1
Takanao Matsumoto, Naoka Umemoto, Hiroaki Sato, Kenjiro Takagi, Hiroyoshi Ko, Tomoko Yamada, Maki Kakurai, Norito Ishii, Takashi Hashimoto, Toshio Demitsu. A case of intractable pemphigoid gestationis that was prolonged after delivery and caused blisters in the neonate. Postepy dermatologii i alergologii. 2023. 40. 2. 333-335
Naoka Umemoto, Toshio Demitsu, Kaoru Otaki, Takanao Matsumoto, Maya Takazawa, Atsushi Yamada, Shun-Ichi Kimura, Maki Kakurai. Dupilumab therapy in Sézary syndrome misdiagnosed as atopic dermatitis: A case report. The Journal of dermatology. 2020. 47. 10. e356-e357
Toshio Demitsu, Naoka Umemoto, Tatsuo Maeda, Maki Kakurai, Kazutoshi Harada. Cutaneous Exophiala oligosperma infection presenting with multiple, rosacea-like papules on the cheek in a healthy individual. The Journal of dermatology. 2020. 47. 8. e308-e310
T. Demitsu, Y. Jinbu, M. Komine, N. Umemoto, M. Kakurai, K. Yoneda, A. Yamamoto, H. Tsuda, M. Ohtsuki, Y. Mori. An ultrastructural study of familial type and non-familial type of white sponge nevus. JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2017. 137. 10. S217-S217
T. Demitsu, K. Yoneda, E. Iida, K. Sasaki, N. Umemoto, M. Kakurai, K. Wakatabi, T. Yamada, B. Ohyama, T. Hashimoto. A case of mucous membrane pemphigoid with IgG antibodies against all the alpha 3, beta 3 and gamma 2 subunits of laminin-332 and BP180 C-terminal domain, associated with pancreatic cancer. CLINICAL AND EXPERIMENTAL DERMATOLOGY. 2009. 34. 8. E992-E994
M. Kakurai, T. Demitsu, E. Iida, N. Umemoto, T. Yamada, K. Yoneda, S. Kako, K. Ohshima, B. Ohyama, T. Hashimoto. Coexistence of paraneoplastic pemphigus and bullous pemphigoid. JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY. 2009. 23. 8. 962-964
Vasoactive intestinal peptide(VIP)regulates its receptor expression and functions of human keratinocytes via type I VIP receptors (Jichi Medical University)
