Shimozawa Nobuhiro

シモザワノブヒロ | Shimozawa Nobuhiro

Affiliation and department：

Research field (3)： Animal production science , Developmental biology , Laboratory animal science

Research keywords (6)：核移植 , ES細胞 , クローン , 実験動物 , 発生工学 , Developmental engineering science

Research theme for competitive and other funds (11)：

2023 - 2026 カニクイザルにおける神経セロイドリポフスチン症モデルのリソース開発
2022 - 2025 網膜色素変性を自然発症するカニクイザルの繁殖と治療法開発への応用
2020 - 2023 Development of research resources in cynomolgus monkeys with neuronal ceroid lipofuscinosis
2019 - 2022 The study of determining the disease pathogenesis and developing the attractive animal disease model using cynomolgus monkeys with retinitis pigmentosa
2017 - 2020 Construction of Cynomologus Monkey Model for Hereditary Retinal Diseases : Diseases Mechanisms and Therapeutic

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Papers (43)：

Yoshiko Munesue, Naohide Ageyama, Nobuyuki Kimura, Ichiro Takahashi, Shunya Nakayama, Sachi Okabayashi, Yuko Katakai, Hiroshi Koie, Ken ichi Yagami, Kazuhiro Ishii, et al. Cynomolgus macaque model of neuronal ceroid lipofuscinosis type 2 disease. Experimental Neurology. 2023. 363
Sana Ando, Masashi Sakurai, Shusaku Shibutani, Nobuyuki Kimura, Nobuhiro Shimozawa, Yasuhiro Yasutomi, Ryotaro Yabe, Takashi Ohama, Koichi Sato. Age-related alterations in protein phosphatase 2A methylation levels in brains of cynomolgus monkeys: a pilot study. Journal of biochemistry. 2023
Nobuhiro Shimozawa, Takeshi Iwata, Yasuhiro Yasutomi. A controlled ovarian stimulation procedure suitable for cynomolgus macaques. Experimental animals. 2022
Shingo Koinuma, Nobuhiro Shimozawa, Yasuhiro Yasutomi, Nobuyuki Kimura. Aging induces abnormal accumulation of Aβ in extracellular vesicle and/or intraluminal membrane vesicle-rich fractions in nonhuman primate brain. Neurobiology of aging. 2021. 106. 268-281
Nobuhiro Shimozawa, Naohide Ageyama, Shunya Nakayama, Hiroshi Koie, Yasuhiro Yasutomi. Ultrasound-guided, Transabdominal, Intrauterine Artificial Insemination for Cynomolgus Macaques (Macaca fascicularis) Based on Estimated Timing of Ovulation. Journal of the American Association for Laboratory Animal Science : JAALAS. 2021. 60. 2. 125-132

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MISC (23)：

棟居佳子, 中山駿矢, 鯉江洋, 八神健一, 揚山直英, 石井一弘, 玉岡晃, 下澤律浩. 神経セロイドリポフスチン症2型カニクイザルにおける経時的な病態変化. 日本実験動物学会総会講演要旨集(Web). 2022. 69th
SHIMOZAWA Nobuhiro, AGEYAMA Naohide, NAKAYAMA Shunya, KOIE Hiroshi, YASUTOMI Yasuhiro. Ultrasound-guided, transabdominal, intrauterine artificial insemination for cynomolgus macaques based on estimated timing of ovulation. Primate Research Supplement. 2021. 37. Supplement. 48-48
Akiko Suga, Mao Nakayama, Zai-Long Chi, Atsushi Mizota, Nobuhiro Shimozawa, Kazutoshi Yoshitake, Takeshi Iwata. Characterization and Genetic Analysis of Cynomolgus Monkeys with Hereditary Macular Drusen. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 2017. 58. 8
高田達之, 吉田真子, 鈴木亨, 下澤律浩, 浅見真紀, 檜垣彰吾, 松田知成, PERRY Anthony, 岡本誉士典. マウス初期胚におけるDNAメチル化動態の定量解析. Journal of Reproduction and Development. 2016. 62. Suppl. j125-j125
藤井裕介, 西口康二, 西口康二, 古川敏紀, 小野文子, 下澤律浩, 東郷睦, 鈴木通弘, 中澤徹, 中澤徹. 2011-2013年に霊長類医科学研究センターで撮影されたサル1443頭の眼底写真の解析. 日本眼科学会雑誌. 2015. 119

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Works (1)：

Production of somatic cloned mice and application to Laboratory Animal Science
1999 -

Professional career (2)：

Master of agriculture (Tokyo University of Agriculture)
Ph.D of exprimental animal science (Tokyo University of Agriculture)

Work history (3)：

2015/04 - 現在 National Institutes of Biomedical Innovation, Health and Nutrition Tsukuba Primate Research Center
2012/01 - 現在 National Institutes of Biomedical Innovation, Health and Nutrition
2005/04 - National Institutes of Biomedical Innovation, Health and Nutrition

Association Membership(s) (5)：

JAPANESE SOCIETY OF MAMMALIAN OVA RESEARCH , PRIMATE SOCIETY OF JAPAN , 日本実験動物学会 , Japanese Society of Animal Science , Japanese Association for Laboratory Animal Science

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