Art

J-GLOBAL ID：200902000460714330   Reference number：91A0130200

Potent inhibition of pepsin and penicillopepsin by phosphorus-containing peptide analogues.

りん含有ペプチド類似体によるペプシンとペニシロペプシンの強力阻害

Author (3)： BARTLETT P A (Univ. California, California) ,  HANSON J E (Univ. California, California) ,  GIANNOUSIS P P (Univ. California, California)
Material： Journal of Organic Chemistry  (J Org Chem)
Volume： 55  Issue： 26  Page： 6268-6274  Publication year： Dec. 21, 1990 
JST Material Number： C0328A  ISSN： 0022-3263  CODEN： JOCEAH  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： pepsin ,...
Semi thesaurus term： penicillopepsin ,...

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JST classification (2)： Peptides  (CF10080G) ,  ヒドロラーゼ【’81~’92】  (EB09050V)

Substance index (17)： (S)-2-[[(R)-1-[(Cbz-L-Ala-L-Ala-)Amino]-3-methylbutyl]phosphonyloxy]-3-phenylpropionic acid methyl ester ,  (S)-2-[[(R)-1-[(Isovaleryl-L-Val-L-Val-)amino]-3-methylbutyl]phosphonyloxy]-3-phenylpropionic acid methyl ester ,  N-[(S)-2-[[(R)-1-[(Cbz-L-Ala-L-Ala-)Amino]-3-methylbutyl]phosphonyloxy]-3-phenylpropionyl]-L-Ala-L-Ala-OMe ,  N-[(S)-2-[[(R)-1-[(Isovaleryl-L-Val-L-Val-)amino]-3-methylbutyl]phosphonyloxy]-3-phenylpropionyl]-L-Ala-L-Ala-OMe ,  [[(R)-2-[(Isovaleryl-L-Val-)amino]-3-methylbutyl]hydroxyphosphinyl]acetic acid ethyl ester ,  [[(R)-2-[(Isovaleryl-L-Val-L-Val-)amino]-3-methylbutyl]hydroxyphosphinyl]acetic acid ethyl ester ,  [[(R)-2-[(Isovaleryl-L-Val-L-Val-)amino]-3-methylbutyl]aminophosphinyl]acetic acid ethyl ester ,  [[(R)-2-[(Isovaleryl-L-Val-)amino]-3-methylbutyl]aminophosphinyl]acetic acid methyl ester ,  [[[(R)-2-[(Isovaleryl-L-Val-)amino]-3-methylbutyl]hydroxyphosphinyl]acetyl]-L-Ala-(3-methylbutyl)-NH₂ ,  [[[(R)-2-[(Isovaleryl-L-Val-)amino]-3-methylbutyl]aminophosphinyl]acetyl]-L-Ala-(3-methylbutyl)-NH₂ ,  [(3S,4S)-4-[(Isovaleryl-L-Val-L-Val-)amino]-3-hydroxy-6-methylheptanoyl]-L-Ala-(3-methylbutyl)-NH₂ ,  [(S)-4-[(Isovaleryl-L-Val-L-Val-)amino]-3-oxo-6-methylheptanoyl]-L-Ala-(3-methylbutyl)-NH₂ ,  [(3S,4S)-4-[(Isovaleryl-L-Val-)amino]-3-hydroxy-6-methylheptanoyl]-L-Ala-(3-methylbutyl)-NH₂ ,  [(3S,4S)-4-[(Isovaleryl-L-Val-L-Val-)amino]-3-hydroxy-6-methylheptanoyl]-L-Phe-OMe ,  (3S,4S)-4-[(Isovaleryl-L-Val-L-Val-)amino]-3-hydroxy-6-methylheptanoic acid ethyl ester ,  [(2S,7S)-2-Amino-7-[(isovaleryl-L-Val-)amino]-6-oxo-5-hydroxy-9-methyldecanoyl]-L-Ala-(3-methylbutyl)-NH₂ ,  [(2S,7S)-7-[(Isovaleryl-L-Val-)amino]-2-amino-9-methyl-5,6-dioxodecanoyl]-L-Ala-(3-methylbutyl)-NH₂

Terms in the title (3)： ペプチド類似体 ,  ペプシン ,  阻害