Physico-chemical properties of new acyl derivatives of tylosin produced by microbial transformation.

OKAMOTO R; FUKUMOTO T; NOMURA H; KIYOSHIMA K; NAKAMURA K; TAKAMATSU A; NAGANAWA H; TAKEUCHI T; UMEZAWA H

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J-GLOBAL ID：200902010113301080 Reference number：81A0042972

Physico-chemical properties of new acyl derivatives of tylosin produced by microbial transformation.

微生物変換によって生産される新タイロシンアシル誘導体の理化学的性状

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Author (9)： , , , , , , , ,
Material：
Volume： 33 Issue： 11 Page： 1300-1308 Publication year： Nov. 1980
JST Material Number： G0489A ISSN： 0021-8820 Document type： Article
Article type：原著論文 Country of issue： Japan (JPN) Language： ENGLISH (EN)

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Antibiotics in general , Structure-activity relationship of drugs

Reference (12)：

1) OMURA, S.; M. KATAGIRI, I. UMEZAWA, K. KOMIYAMA, K. SEKIKAWA, A. MATSUMAE & T. HATA: Structural-biological activities relationship among leucomycins and their derivatives. J. Antibiotics 21: 532-538, 1968
3) MCGUIR, R. B.; W. S. BONECE, C. E. HIGENS, M. N. HOHEN, W. N. STARK, J. WESTHEAD & R. N. WOLFE: Tylosin, a new antibiotic. I. Microbiological studies. Antibiot. & Chemoth. 11: 320-327, 1961
4) MORIN, R. B.; M. GERMAN, R. L. HAMILL & P. V. DEMARCO: The structures of tylosin. Tetrahed. Lett. 1970: 4737-4740, 1970
5) OMURA. S.; A. NAKAGAWAM, M. OTANI,T . HATA, H. OGURA & K. FURUHATA: Structure of the spiramycins (foromacidins) and their relationship with the leucomycins and carbomycins (magnamycins). J. Am. Chem. Soc. 91: 3401-3409, 1969
6) OMURA, S.; A. NAKAGAWA, A. NESZEMLYI, S. D. GERO, K. FURUHATA, F. PIRIOU & G. LUKACS: Carbon-13 nuclear magnetic resonance spectral analysis of 16-membered macrolide antibiotics. J. Am. Chem. Soc. 97: 4001-4009, 1975

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