Art

J-GLOBAL ID：200902029497685885   Reference number：91A0696698

Design, Synthesis, and Pharmacological Evaluation of Ultrashort- to Long-Acting Opioid Analgetics.

極短ないし長時間活性オピオイド鎮痛剤のデザイン,合成および薬理学的評価

Author (9)： FELDMAN P L (Glaxo Research Inst., North Carolina) ,  JAMES M K (Glaxo Research Inst., North Carolina) ,  BRACKEEN M F (Glaxo Research Inst., North Carolina) ,  BILOTTA J M (Glaxo Research Inst., North Carolina) ,  SCHUSTER S V (Glaxo Research Inst., North Carolina) ,  LAHEY A P (Glaxo Research Inst., North Carolina) ,  LUTZ M W (Glaxo Research Inst., North Carolina) ,  JOHNSON M R (Glaxo Research Inst., North Carolina) ,  LEIGHTON H J (Glaxo Research Inst., North Carolina)
Material： Journal of Medicinal Chemistry  (J Med Chem)
Volume： 34  Issue： 7  Page： 2202-2208  Publication year： Jul. 1991 
JST Material Number： D0102A  ISSN： 0022-2623  CODEN： JMCMAR  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： narcotic analgesic ,...
Semi thesaurus term： esterase ,...

   To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=91A0696698&from=J-GLOBAL&jstjournalNo=D0102A") }}

JST classification (1)： Basic research of addictive analgesics and narcotics  (GW03080Z)

Substance index (29)： 4-(N-Phenyl-N-propanoylamino)piperidine-1-acetic acid methyl ester ,  4-(N-Phenyl-N-propanoylamino)piperidine-1-propionic acid methyl ester ,  4-(N-Phenyl-N-propanoylamino)piperidine-1-butyric acid methyl ester ,  4-(N-Phenyl-N-propanoylamino)piperidine-1-valeric acid methyl ester ,  4-(N-Phenyl-N-propanoylamino)piperidine-1-propionic acid ,  4-Methoxycarbonyl-4-(N-phenyl-N-propanoylamino)piperidine-1-acetic acid methyl ester ,  Remifentanil ,  4-Methoxymethyl-4-(N-phenyl-N-propanoylamino)piperidine-1-propionic acid methyl ester ,  4-Methoxycarbonyl-4-(N-phenyl-N-propanoylamino)piperidine-1-butyric acid methyl ester ,  4-Methoxycarbonyl-4-(N-phenyl-N-propanoylamino)piperidine-1-valeric acid methyl ester ,  G-190291 ,  G-195779 ,  4-Methoxycarbonyl-4-(N-phenyl-N-propanoylamino)piperidine-1-propionic acid propyl ester ,  4-Methoxycarbonyl-4-(N-phenyl-N-propanoylamino)piperidine-1-propionic acid isopropyl ester ,  4-Methoxycarbonyl-4-(N-phenyl-N-propanoylamino)piperidine-1-propionic acid butyl ester ,  4-Methoxycarbonyl-4-(N-phenyl-N-propanoylamino)piperidine-1-propionic acid 1-methylpropyl ester ,  4-Methoxycarbonyl-4-(N-phenyl-N-propanoylamino)piperidine-1-propionic acid 2-methylpropyl ester ,  4-Methoxycarbonyl-4-(N-phenyl-N-propanoylamino)piperidine-1-propionic acid tert-butyl ester ,  4-Methoxycarbonyl-4-(N-phenyl-N-propanoylamino)piperidine-1-propionic acid pentyl ester ,  4-Methoxycarbonyl-4-(N-phenyl-N-propanoylamino)piperidine-1-propionic acid 2-methylbutyl ester ,  4-Methoxycarbonyl-4-(N-phenyl-N-propanoylamino)piperidine-1-propionic acid 3-methylbutyl ester ,  4-Methoxycarbonyl-4-(N-phenyl-N-propanoylamino)piperidine-1-propionic acid 2,2-dimethylpropyl ester ,  4-Methoxycarbonyl-4-(N-phenyl-N-propanoylamino)piperidine-1-propionic acid hexyl ester ,  4-Methoxycarbonyl-4-(N-phenyl-N-propanoylamino)piperidine-1-propionic acid heptyl ester ,  4-Methoxycarbonyl-4-(N-phenyl-N-propanoylamino)piperidine-1-propionic acid octyl ester ,  Fentanyl ,  Sufentanil ,  Alfentanil ,  Carfentanil

Terms in the title (6)： 長時間 ,  活性 ,  オピオイド鎮痛剤 ,  デザイン ,  薬理学 ,  評価