Art

J-GLOBAL ID：200902032702840113   Reference number：88A0219657

Tetrahydroisoquinoline and 1-methyl-tetrahydroisoquinoline are present in the human brain: Relation to parkinson’s disease.

テトラヒドロイソキノリン及び1-メチル-テトラヒドロイソキノリンはヒト脳内に存在する パーキンソン病との関連性

Author (5)： OHTA S (Univ. Tokyo, Tokyo, JPN) ,  KOHNO M (Univ. Tokyo, Tokyo, JPN) ,  MAKINO Y (Univ. Tokyo, Tokyo, JPN) ,  TACHIKAWA O (Univ. Tokyo, Tokyo, JPN) ,  HIROBE M (Univ. Tokyo, Tokyo, JPN)
Material： Biomedical Research  (Biomed Res)
Volume： 8  Issue： 6  Page： 453-456  Publication year： Dec. 1987 
JST Material Number： Z0236B  ISSN： 0388-6107  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human ,...
Semi thesaurus term： tetrahydroisoquinoline ,...

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JST classification (2)： Central nervous system  (EJ12030F) ,  中枢神経系の疾患【’81~’92】  (GN03020K)

Reference (10)：

• 1 CALNE D. B., EISEN A., MCGEER E. and SPENCER P. (1986) Alzheimer’s disease, Parkinson’s disease, and motoneurone disease: abiotropic interaction between ageing and environment? Lancet II, 1067-1070
• 2 CALNE D. B. and LANGSTON J. W. (1983) Aetiology of Parkinson’s disease. Lancet II, 1457-1459
• 3 KOHNO M., OHTA S. and HIROBE M. (1986) Tetrahydroisoquinoline and 1-methyl-tetrahydroisoquinoline as novel endogenous amines in rat brain. Biochem. Biophys. Res. Commum. 140, 448-454
• 4 LANGSTON J. W., BALLARD P., TETRUD J. W. and IRWIN I. (1983) Chronic parkinsonism in humans due to a product of meperidine-analog synthesis. Science 219, 979-980
• 5 LANGSTON J. W. and IRWIN I. (1986) MPTP: Current concepts and controversies. Clin. Neuropharmacol. 9, 485-507

Terms in the title (4)： テトラヒドロイソキノリン ,  ヒト ,  パーキンソン病 ,  関連性