Art

J-GLOBAL ID：200902065785304418   Reference number：91A0529110

Synthesis of Nucleosides and Related Compounds. Part XX. Synthesis of Carbocyclic Nucleosides from 2-Azabicyclo〔2.2.1〕hept-5-en-3-ones: Sodium Borohydride-Mediated Carbon-Nitrogen Bond Cleavage of Five-and Six-Membered Lactams.

ヌクレオシド及び関連化合物の合成 XX 2-アザビシクロ[2.2.1]ヘプタ-5-エン-3-オンからの炭素環式ヌクレオシドの合成 ヒドリドほう酸ナトリウムによる五および六員環ラクトンの炭素-窒素結合開裂反応

Author (5)： KATAGIRI N (Tohoku Univ., Sendai, JPN) ,  MUTO M (Tohoku Univ., Sendai, JPN) ,  NOMURA M (Tohoku Univ., Sendai, JPN) ,  HIGASHIKAWA T (Tohoku Univ., Sendai, JPN) ,  KANEKO C (Tohoku Univ., Sendai, JPN)
Material： Chemical and Pharmaceutical Bulletin  (Chemical & Pharmaceutical Bulletin)
Volume： 39  Issue： 5  Page： 1112-1122  Publication year： May. 1991 
JST Material Number： G0504A  ISSN： 0009-2363  CODEN： CPBTAL  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： chemical synthesis ,...
Semi thesaurus term： bridged compound ,...

   To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=91A0529110&from=J-GLOBAL&jstjournalNo=G0504A") }}

JST classification (4)： Pyrimidines  (CF07103W) ,  Purines,pteridines  (CF07105E) ,  Condensed derivatives of pyrroles  (CF07077C) ,  Basic research of antiviral drugs  (GW17040O)

Substance index (24)： 2-Azabicyclo[2.2.1]hept-5-en-3-one ,  2-Tosyl-2-azabicyclo[2.2.1]hept-5-en-3-one ,  2-[(Chloroacetylamino)carbonyl]-2-azabicyclo[2.2.1]hept-5-en-3-one ,  2-Carbamoyl-2-azabicyclo[2.2.1]hept-5-en-3-one ,  2-(Methylcarbamoyl)-2-azabicyclo[2.2.1]hept-5-en-3-one ,  2-(Benzylcarbamoyl)-2-azabicyclo[2.2.1]hept-5-en-3-one ,  (1S)-1α-(Hydroxymethyl)-4α-[tosylamino]cyclopenta-2-ene ,  (1S)-1α-(Hydroxymethyl)-4α-[[(chloroacetylamino)carbonyl]amino]cyclopenta-2-ene ,  (1S)-1α-(Hydroxymethyl)-4α-[carbamoylamino]cyclopenta-2-ene ,  (1S)-1α-(Hydroxymethyl)-4α-[(methylcarbamoyl)amino]cyclopenta-2-ene ,  (1S)-1α-(Hydroxymethyl)-4α-[(benzylcarbamoyl)amino]cyclopenta-2-ene ,  1-[(1S)-3α-(tert-Butyldimethylsilyloxymethyl)cyclopentyl]-3-methyluracil ,  3-[(1S)-3α-(tert-Butyldimethylsilyloxymethyl)cyclopentyl]-1-methyluracil ,  1-[(1R)-2α,3α-Dihydroxy-4β-(hydroxymethyl)cyclopentyl]-3-methyluracil ,  1-[(1R)-2α,3α-Dihydroxy-4β-(hydroxymethyl)cyclopentyl]-3-benzyluracil ,  1-[(1S)-3α-(tert-Butyldimethylsilyloxymethyl)cyclopentyl]uracil ,  3-[(1S)-3α-(tert-Butyldimethylsilyloxymethyl)cyclopentyl]uracil ,  1-[(1S)-3α-(Hydroxymethyl)cyclopentyl]uracil ,  (1S,5R)-3,3-Dimethyl-6α-(carbamoylamino)-8α-(tert-butyldimethylsilyloxymethyl)-2,4-dioxabicyclo[3.3.0]octane ,  1-[(1R)-2α,3α-Dihydroxy-4β-(hydroxymethyl)cyclopentyl]-5-methyluracil ,  (1R)-1β-(Acetylamino)-2α,3α-bis(acetoxy)-4β-(acetoxymethyl)cyclopentane ,  (1R)-N-Acetyl-4β-(hydroxymethyl)-2-cyclopenten-1β-amine ,  (1R)-N-Acetyl-4β-(acetoxymethyl)-2-cyclopenten-1β-amine ,  (-)-Carbovir

Reference (44)：

• 1) Part XIX: N. Katagiri, M. Yamamoto, and C. Kaneko, Chem. Lett., 1990, 1855.
• 2) V.E. Marquez and M.-I. Lim, Med. Res. Rev., 6, 1 (1986).
• 3) T. Sato and R. Noyori, Yuki Gosei Kagaku Kyokai Shi, 38, 862, 947 (1980)
• K.A. Watanabe, Yuki Gosei Kagaku Kyokai Shi, 45, 212 (1987)
• J.G. Buchanan, Forch. Chem. Org. Naturst., 44, 243 (1983).

Terms in the title (9)： ヌクレオシド ,  関連化合物 ,  炭素環 ,  ヒドリドほう酸ナトリウム ,  六員環 ,  ラクトン ,  炭素 ,  窒素 ,  結合開裂反応