Art

J-GLOBAL ID：200902073004414976   Reference number：88A0227880

New antitumor antibiotic, LL-D05139β. Fermentation. isolation, structure determination and biological activities.

新規の抗腫よう抗生物質,LL-D05139β 発酵,単離,構造決定および生物学的活性

Author (6)： LEE M D (American Cyanamid Co., NY, USA) ,  FANTINI A A (American Cyanamid Co., NY, USA) ,  KUCK N A (American Cyanamid Co., NY, USA) ,  GREENSTEIN M (American Cyanamid Co., NY, USA) ,  TESTA R T (American Cyanamid Co., NY, USA) ,  BORDERS D B (American Cyanamid Co., NY, USA)
Material： Journal of Antibiotics  (J Antibiot)
Volume： 40  Issue： 12  Page： 1657-1663  Publication year： Dec. 1987 
JST Material Number： G0489A  ISSN： 0021-8820  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： antineoplastic antibiotics ,...
Semi thesaurus term： LL-D05139ベータ ,...

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JST classification (1)： Basic research of antitumor(=antineoplastic)antibiotics  (GX05040Y)

Reference (15)：

• 1) LABEDA, D. P.; R. T. TESTA, M. P. LECHEVALIER & H. A. LECHEVALIER: Glycomyces, a new genus of the Actinomycetales. Int. J. Syst. Bacteriol. 35: 417-421, 1985
• 2) SCHMITT-SLOMSKA, J.: L-Forms as models for the study of antibiotic activities. Microbiol. Ser. 17: 229-262, 1986
• 3) ELESPURU, R. K. & M. B. YARMOLINSKY: A colorimetric assay of lysogenic induction designed for screening potential carcinogenic and carcinostatic agents. Environ. Mutagen. 1: 55 - 78, 1979
• 4) ELESPURU, R. K. & R. J. WHITE: Biochemical prophage induction assay: A rapid test for antitumor agents that interact with DNA. Cancer Res. 43: 2819-2830, 1983
• 5) LEE, M. D. & D. B. BORDERS: LL-D05139β, a new antitumor antibiotic: Isolation and structure determination. Program and Abstracts of the 24th Intersci. Conf. on Antimicrob. Agents Chemother., No. 1144, p. 293, Washington, D.C., Oct. 8-10, 1984

Terms in the title (4)： 抗腫よう抗生物質 ,  発酵 ,  単離 ,  生物学的活性