Art

J-GLOBAL ID：200902075935393010   Reference number：82A0062667

Aminoglycoside antibiotics. XIV synthesis and activity of 6-O-(3-amino-3-deoxy-α-D-glucopyranosyl)- and 5-O-(β-D-ribofuranosyl)apramycins.

アミノグリコシド系抗生物質 XIV 6-O-(3-アミノ-3-デオキシ-α-D-グルコピラノシル)-および5-O-(β-D-リボフラノシル)アプラマイシン類の合成と活性

Author (4)： ABE Y (Bristol-Banyu Research Inst. Ltd., Tokyo) ,  NAKAGAWA S (Bristol-Banyu Research Inst. Ltd., Tokyo) ,  NAITO T (Bristol-Banyu Research Inst. Ltd., Tokyo) ,  KAWAGUCHI H (Bristol-Banyu Research Inst. Ltd., Tokyo)
Material： Journal of Antibiotics  (J Antibiot)
Volume： 34  Issue： 11  Page： 1434-1446  Publication year： Nov. 1981 
JST Material Number： G0489A  ISSN： 0021-8820  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： aminoglycoside antibiotics ,...
Semi thesaurus term： apramycin

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JST classification (2)： Basic research of antibiotics acting on pathogenic organisms  (GX05020C) ,  Synthesis of antibiotics  (GX04000Z)

Reference (21)：

• 1) O'CONNER, S.; L. K. T. LAM, N. D. JONES & M. O. CHANEY: Apramycin, a unique aminocyclitol antibiotic.J. Org. Chem. 41: 2087-2092, 1976
• 2) WICK, W. E. & J. S. WELLES: Nebramycin, a new broad-spectrum antibiotic complex. IV. In vitro andin vivo laboratory evaluation. Antimicr. Agents & Chernoth. 1967: 341- 348, 1968
• 3) PRICE, K. E.; J. C. GODFREY & H. KAWAGUCHI: Effect of structural modifications on the biological prop1446 THE JOURNAL OF ANTIBIOTICS NOV. 1981erties of aminoglycoside antibiotics containing 2-deoxystreptamine. In D. PERLMAN (ed.), "Structure-activityRelationships among the Semi-synthetic Antibiotics", pp. 239-355 and 357-395, Academic Press,New York, 1977
• 4) HASEGAWA, A.; N. KURIHARA, D. NISHIMURA & M. NAKAJIMA: Synthetic studies on carbohydrate antibiotics.IX. Synthesis of kanamycin A and related compounds. Agric. Biol. Chem. 32: 1130-1134,1968
• 5) UMEZAWA, S.; S. KOTO, K. TATSUTA. H. HINENO, Y. NISHIMURA & T. TSUMURA: Studies on aminosugars.XXIII. The total synthesis of kanamycin B. Bull. Chem. Soc. Japan 42: 537-541, 1969

Terms in the title (3)： アミノグリコシド系抗生物質 ,  アプラマイシン ,  活性