Art

J-GLOBAL ID：200902083158664032   Reference number：90A0162437

Probucol-induced QT prolongation and torsades de pointes.

ProbucolによるQT延長とTorsade de Pointes

Author (7)： MATSUHASHI H (Asahikawa Medical Coll., Asahikawa) ,  ONODERA S (Asahikawa Medical Coll., Asahikawa) ,  KAWAMURA Y (Asahikawa Medical Coll., Asahikawa) ,  HASEBE N (Asahikawa Medical Coll., Asahikawa) ,  KOHMURA C (Asahikawa Medical Coll., Asahikawa) ,  YAMASHITA H (Asahikawa Medical Coll., Asahikawa) ,  TOBISE K (Asahikawa Medical Coll., Asahikawa)
Material： Japanese Journal of Medicine  (Jpn J Med)
Volume： 28  Issue： 5  Page： 612-615  Publication year： Sep. 1989 
JST Material Number： Z0157B  ISSN： 0021-5120  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human ,...
Semi thesaurus term： WPW syndrome ,...

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JST classification (1)： 心臓の疾患【’81~’92】  (GJ03020Y)

Reference (8)：

• 1) Barber M, Mueller T, Gilmour RF Jr, et al: Electrophysiologic effects of probucol on monkey ventricle (abstr). Circulation (Suppl. IV) 64: 123, 1981.
• 2) Marshall FN, Lewis JE: Sensitization to epinephrine-induced ventricular fibrillation produced by probucol, in dogs. Toxicol Appl Pharmacol 24: 594, 1973.
• 3) Elharrar V, Watanabe AM, Molello J, et al: Adrenergically mediated ventricular fibrillation in probucol-treated dogs, roles of alpha and beta adrenergic receptors. PACE 2: 435, 1979.
• 4) Marshall FN: Pharmacology and toxicology of probucol. Artery 10: 7, 1982.
• 5) Bronwe KF, Prystowsky EN, Heger JJ, et al: Prolongation of the QT interval induced by probucol, demonstration of a method for determining QT interval change induced by a drug. Am Heart J 107: 680, 1984.

Terms in the title (1)： QT延長