Art

J-GLOBAL ID：200902086896314843   Reference number：90A0451961

Comparison of cardiovascular effects of pirmenol with those of disopyramide in isolated canine heart preparations cross-circulated with a donor dog.

供血犬と交叉循環した摘出イヌ心臓標本におけるピルメノールとジソピラミドの心臓血管効果の比較

Author (4)： SUGIYAMA A (Yamanashi Medical Coll., Yamanashi, JPN) ,  MOTOMURA S (Yamanashi Medical Coll., Yamanashi, JPN) ,  TAMURA K (Yamanashi Medical Coll., Yamanashi, JPN) ,  HASHIMOTO K (Yamanashi Medical Coll., Yamanashi, JPN)
Material： Japanese Journal of Pharmacology  (Jpn J Pharmacol)
Volume： 53  Issue： 1  Page： 97-110  Publication year： May. 1990 
JST Material Number： G0813A  ISSN： 0021-5198  CODEN： JJPAA  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： antiarrhythmic drug ,...
Semi thesaurus term： coronary artery ,...

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JST classification (1)： Basic research of cardioactive drugs  (GW07020N)

Reference (18)：

• 1) Dukes, I.D., Vaughan Williams, E.M. and Dennis, P.D.: Electrophysiological and cardiovascular effects of pirmenol, a new class I antiarrhythmic drug. J. Cardiovasc. Pharmacol. 8, 227-234 (1986)
• 2) Reder, R.F., Danilo, P., Jr. and Rosen, M.R.: Effects of pirmenol HCl on electrophysiologic properties of cardiac Purkinje fibers. Eur. J. Pharmacol. 61, 321-333 (1980)
• 3) Steffe, T.J., Mertz, T.E., Hastings, S.G., Potoczak, R.E. and Kaplan, H.R.: Cl-845 (pirmenol hydrochloride): A new orally effective long-acting antiarrhythmic agent. J. Pharmacol. Exp. Ther. 214, 50-57 (1980)
• 4) Mertz, T.E. and Steffe, T.J.: Pirmenol hydrochloride (Cl-845): Antiarrhythmic profile in coronary artery ligated conscious dogs. J. Cardiovasc. Pharmacol. 2, 527-541 (1980)
• 5) Hashimoto, K., Watanabe, K. and Sugiyama, A.: Antiarrhythmic plasma concentrations of pirmenol on canine ventricular arrhythmias. Japan. J. Pharmacol. 48, 273-282 (1988)

Terms in the title (8)： 交叉循環 ,  摘出 ,  イヌ ,  心臓 ,  標本 ,  ピルメノール ,  ジソピラミド ,  心臓血管効果