Art

J-GLOBAL ID：200902099880739253   Reference number：92A0437647

Novel non-nucleoside inhibitors of HIV-1 reverse transcriptase. 2. Tricyclic pyridobenzoxazepinones and dibenzoxazepinones.

HIV-1リバーストランスクリプターゼの新しい非ヌクレオシド系阻害薬 2 三環式ピリドベンゾオキサゼピノン類およびジベンゾオキサゼピノン類

Author (9)： KLUNDER J M (Boehringer Ingelheim Pharmaceuticals, Inc., Connecticut, USA) ,  HARGRAVE K D (Boehringer Ingelheim Pharmaceuticals, Inc., Connecticut, USA) ,  WEST M (Boehringer Ingelheim Pharmaceuticals, Inc., Connecticut, USA) ,  CULLEN E (Boehringer Ingelheim Pharmaceuticals, Inc., Connecticut, USA) ,  PAL K (Boehringer Ingelheim Pharmaceuticals, Inc., Connecticut, USA) ,  BEHNKE M L (Boehringer Ingelheim Pharmaceuticals, Inc., Connecticut, USA) ,  KAPADIA S R (Boehringer Ingelheim Pharmaceuticals, Inc., Connecticut, USA) ,  MCNEIL D W (Boehringer Ingelheim Pharmaceuticals, Inc., Connecticut, USA) ,  ADAMS J (Boehringer Ingelheim Pharmaceuticals, Inc., Connecticut, USA)
Material： Journal of Medicinal Chemistry  (J Med Chem)
Volume： 35  Issue： 10  Page： 1887-1897  Publication year： May. 15, 1992 
JST Material Number： D0102A  ISSN： 0022-2623  CODEN： JMCMAR  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： antiviral action ,...
Semi thesaurus term： ジベンゾオキサゼピノン ,...

   To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=92A0437647&from=J-GLOBAL&jstjournalNo=D0102A") }}

JST classification (1)： Basic research of antiviral drugs  (GW17040O)

Substance index (82)： 10-Propyldibenz[b,f][1,4]oxazepin-11(10H)-one ,  5-(2-Methylpropyl)pyrido[2,3-b][1,4]benzoxazepin-6(5H)-one ,  6-Propylpyrido[2,3-b][1,5]benzoxazepin-5(6H)-one ,  10-Propyldibenzo[b,f][1,4]thiazepin-11(10H)-one ,  10,11-Dihydro-11-oxo-10-propyldibenzo[b,f][1,4]thiazepine 5-oxide ,  10,11-Dihydro-11-oxo-10-propyldibenzo[b,f][1,4]thiazepine 5,5-dioxide ,  Dibenz[b,f][1,4]oxazepin-11(10H)-one ,  10-Methyldibenz[b,f][1,4]oxazepin-11(10H)-one ,  10-Ethyldibenz[b,f][1,4]oxazepin-11(10H)-one ,  10-(2-Propenyl)dibenz[b,f][1,4]oxazepin-11(10H)-one ,  10-Isopropyldibenz[b,f][1,4]oxazepin-11(10H)-one ,  10-Hydroxydibenz[b,f][1,4]oxazepin-11(10H)-one ,  10-Methoxydibenz[b,f][1,4]oxazepin-11(10H)-one ,  2-Cyano-10-methyldibenz[b,f][1,4]oxazepin-11(10H)-one ,  2-Aminomethyl-10-methyldibenz[b,f][1,4]oxazepin-11(10H)-one ,  2-Amino-10-methyldibenz[b,f][1,4]oxazepin-11(10H)-one ,  2-Amino-10-ethyldibenz[b,f][1,4]oxazepin-11(10H)-one ,  10-Ethyl-2-nitrodibenz[b,f][1,4]oxazepin-11(10H)-one ,  10-Methyl-2-methylaminodibenz[b,f][1,4]oxazepin-11(10H)-one ,  3-Amino-10-methyldibenz[b,f][1,4]oxazepin-11(10H)-one ,  7-Amino-10-methyldibenz[b,f][1,4]oxazepin-11(10H)-one ,  7,10-Dimethyldibenz[b,f][1,4]oxazepin-11(10H)-one ,  9,10-Dimethyldibenz[b,f][1,4]oxazepin-11(10H)-one ,  2-Amino-7,10-dimethyldibenz[b,f][1,4]oxazepin-11(10H)-one ,  2-Amino-7-methyl-10-propyldibenz[b,f][1,4]oxazepin-11(10H)-one ,  2-Amino-10-ethyl-8-methyldibenz[b,f][1,4]oxazepin-11(10H)-one ,  2-Amino-8-methyl-10-propyldibenz[b,f][1,4]oxazepin-11(10H)-one ,  2-Amino-9-methyldibenz[b,f][1,4]oxazepin-11(10H)-one ,  2-Amino-10-ethyl-9-methyldibenz[b,f][1,4]oxazepin-11(10H)-one ,  10-Propyldibenz[b,f][1,4]oxazepine-11(10H)-thione ,  10-Ethyl-10,11-dihydrodibenz[b,f][1,4]oxazepine ,  2-Amino-9-methyl-10-propyldibenz[b,f][1,4]oxazepin-11(10H)-one ,  2-Amino-7,8-dimethyl-10-propyldibenz[b,f][1,4]oxazepin-11(10H)-one ,  2-Amino-8,9-dimethyl-10-propyldibenz[b,f][1,4]oxazepin-11(10H)-one ,  2-Amino-6,8-dimethyl-10-propyldibenz[b,f][1,4]oxazepin-11(10H)-one ,  2-Amino-7,9,10-trimethyldibenz[b,f][1,4]oxazepin-11(10H)-one ,  2-Amino-10-ethyl-7,9-dimethyldibenz[b,f][1,4]oxazepin-11(10H)-one ,  2-Hydroxy-7,10-dimethyldibenz[b,f][1,4]oxazepin-11(10H)-one ,  2-Cyano-7,10-dimethyldibenz[b,f][1,4]oxazepin-11(10H)-one ,  7,9-Dimethyldibenz[b,f][1,4]oxazepin-11(10H)-one ,  7,9,10-Trimethyldibenz[b,f][1,4]oxazepin-11(10H)-one ,  2-Cyano-7,9,10-trimethyldibenz[b,f][1,4]oxazepin-11(10H)-one ,  2-Hydroxy-7,9,10-trimethyldibenz[b,f][1,4]oxazepin-11(10H)-one ,  6-Methylpyrido[2,3-b][1,5]benzoxazepin-5(6H)-one ,  2-クロロ-6-メチルピリド[2,3-b][1,5]ベンゾオキサゼピン-5(6H)-オン ,  2-クロロ-6-エチルピリド[2,3-b][1,5]ベンゾオキサゼピン-5(6H)-オン ,  2-クロロ-6-プロピルピリド[2,3-b][1,5]ベンゾオキサゼピン-5(6H)-オン ,  2-クロロ-6-(2-メチルチオエチル)ピリド[2,3-b][1,5]ベンゾオキサゼピン-5(6H)-オン ,  2,4,6-トリメチルピリド[2,3-b][1,5]ベンゾオキサゼピン-5(6H)-オン ,  6-Ethylpyrido[2,3-b][1,5]benzoxazepin-5(6H)-one ,  6-(2-Propenyl)pyrido[2,3-b][1,5]benzoxazepin-5(6H)-one ,  9-Methylpyrido[2,3-b][1,5]benzoxazepin-5(6H)-one ,  6,9-Dimethylpyrido[2,3-b][1,5]benzoxazepin-5(6H)-one ,  9-Fluoro-6-methylpyrido[2,3-b][1,5]benzoxazepin-5(6H)-one ,  6-Methyl-9-nitropyrido[2,3-b][1,5]benzoxazepin-5(6H)-one ,  9-Amino-6-methylpyrido[2,3-b][1,5]benzoxazepin-5(6H)-one ,  9-Dimethylamino-6-methylpyrido[2,3-b][1,5]benzoxazepin-5(6H)-one ,  9-Hydroxy-6-methylpyrido[2,3-b][1,5]benzoxazepin-5(6H)-one ,  9-Methoxy-6-methylpyrido[2,3-b][1,5]benzoxazepin-5(6H)-one ,  7-Cyano-6-methylpyrido[2,3-b][1,5]benzoxazepin-5(6H)-one ,  6-Ethyl-7-nitropyrido[2,3-b][1,5]benzoxazepin-5(6H)-one ,  7-Amino-6-ethylpyrido[2,3-b][1,5]benzoxazepin-5(6H)-one ,  6,9-Dimethyl-3-nitropyrido[2,3-b][1,5]benzoxazepin-5(6H)-one ,  3-Amino-6,9-dimethylpyrido[2,3-b][1,5]benzoxazepin-5(6H)-one ,  3-Amino-6,8,9-trimethylpyrido[2,3-b][1,5]benzoxazepin-5(6H)-one ,  3-Amino-6-ethyl-8,9-dimethylpyrido[2,3-b][1,5]benzoxazepin-5(6H)-one ,  3-Amino-6-isopropyl-8,9-dimethylpyrido[2,3-b][1,5]benzoxazepin-5(6H)-one ,  3-Amino-6,7,9-trimethylpyrido[2,3-b][1,5]benzoxazepin-5(6H)-one ,  3-Amino-6-ethyl-7,9-dimethylpyrido[2,3-b][1,5]benzoxazepin-5(6H)-one ,  6-Ethyl-7,9-dimethylpyrido[2,3-b][1,5]benzoxazepine-5(6H)-thione ,  6-Ethyl-9-methyl-7-nitropyrido[2,3-b][1,5]benzoxazepin-5(6H)-one ,  7-Amino-6-ethyl-9-methylpyrido[2,3-b][1,5]benzoxazepin-5(6H)-one ,  7-Cyano-6-ethyl-9-methylpyrido[2,3-b][1,5]benzoxazepin-5(6H)-one ,  7-Cyano-6,9-dimethylpyrido[2,3-b][1,5]benzoxazepin-5(6H)-one ,  6,9-Dimethyl-7-nitropyrido[2,3-b][1,5]benzoxazepin-5(6H)-one ,  7-Amino-6,9-dimethylpyrido[2,3-b][1,5]benzoxazepin-5(6H)-one ,  7-Hydroxymethyl-6,9-dimethylpyrido[2,3-b][1,5]benzoxazepin-5(6H)-one ,  6,9-Dimethyl-7-methylsulfonylpyrido[2,3-b][1,5]benzoxazepin-5(6H)-one ,  5,6-Dihydro-6,9-dimethyl-5-oxopyrido[2,3-b][1,5]benzoxazepine-7-carboxylic acid methyl ester ,  5,6-Dihydro-6,9-dimethyl-5-oxopyrido[2,3-b][1,5]benzoxazepine-7-carboxamide ,  5,6-Dihydro-6,9-dimethyl-5-oxopyrido[2,3-b][1,5]benzoxazepine-7-carbimidic acid methyl ester ,  5,6-Dihydro-6,9-dimethyl-5-oxopyrido[2,3-b][1,5]benzoxazepine-7-carboxylic acid

Terms in the title (5)： HIV-1 ,  リバーストランスクリプターゼ ,  ヌクレオシド ,  阻害薬 ,  三環