The cyclo-oxygenase-2 inhibitor celecoxib perturbs intracellular calcium by inhibiting endoplasmic reticulum Ca<sup>2+</sup>-ATPases: A plausible link with its anti-tumour effect and cardiovascular risks.

JOHNSON A J; HSU A-L; LIN H-P; SONG X; CHEN C-S

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J-GLOBAL ID：200902101976805413 Reference number：02A0804495

The cyclo-oxygenase-2 inhibitor celecoxib perturbs intracellular calcium by inhibiting endoplasmic reticulum Ca²⁺-ATPases: A plausible link with its anti-tumour effect and cardiovascular risks.

シクロオキシゲナーゼ-2阻害剤セレコキシブは小胞体Ca²⁺ATPアーゼを阻害することで細胞内カルシウム状態を不安定化させるその抗腫よう効果と心臓血管リスクのもっともらしい相関

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Author (5)： , , , ,
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Volume： 366 Issue： 3 Page： 831-837 Publication year： Sep. 15, 2002
JST Material Number： B0205A ISSN： 0264-6021 CODEN： BIJOAK Document type： Article
Article type：原著論文 Country of issue： United Kingdom (GBR) Language： ENGLISH (EN)

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Basic research of enzyme preparations and enzyme inhibitor preparations , Basic research of antitumor(=antineoplastic)drugs

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The cyclo-oxygenase-2 inhibitor celecoxib perturbs intracellular calcium by inhibiting endoplasmic reticulum Ca2+-ATPases: A plausible link with its anti-tumour effect and cardiovascular risks.

The cyclo-oxygenase-2 inhibitor celecoxib perturbs intracellular calcium by inhibiting endoplasmic reticulum Ca²⁺-ATPases: A plausible link with its anti-tumour effect and cardiovascular risks.